ID   E5RG23_HUMAN            Unreviewed;        85 AA.
AC   E5RG23;
DT   08-FEB-2011, integrated into UniProtKB/TrEMBL.
DT   05-OCT-2016, sequence version 8.
DT   16-JAN-2019, entry version 51.
DE   SubName: Full=High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A {ECO:0000313|Ensembl:ENSP00000430262};
DE   Flags: Fragment;
GN   Name=PDE7A {ECO:0000313|Ensembl:ENSP00000430262};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000430262, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000430262, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16421571; DOI=10.1038/nature04406;
RA   Nusbaum C., Mikkelsen T.S., Zody M.C., Asakawa S., Taudien S.,
RA   Garber M., Kodira C.D., Schueler M.G., Shimizu A., Whittaker C.A.,
RA   Chang J.L., Cuomo C.A., Dewar K., FitzGerald M.G., Yang X.,
RA   Allen N.R., Anderson S., Asakawa T., Blechschmidt K., Bloom T.,
RA   Borowsky M.L., Butler J., Cook A., Corum B., DeArellano K.,
RA   DeCaprio D., Dooley K.T., Dorris L. III, Engels R., Glockner G.,
RA   Hafez N., Hagopian D.S., Hall J.L., Ishikawa S.K., Jaffe D.B.,
RA   Kamat A., Kudoh J., Lehmann R., Lokitsang T., Macdonald P.,
RA   Major J.E., Matthews C.D., Mauceli E., Menzel U., Mihalev A.H.,
RA   Minoshima S., Murayama Y., Naylor J.W., Nicol R., Nguyen C.,
RA   O'Leary S.B., O'Neill K., Parker S.C., Polley A., Raymond C.K.,
RA   Reichwald K., Rodriguez J., Sasaki T., Schilhabel M., Siddiqui R.,
RA   Smith C.L., Sneddon T.P., Talamas J.A., Tenzin P., Topham K.,
RA   Venkataraman V., Wen G., Yamazaki S., Young S.K., Zeng Q.,
RA   Zimmer A.R., Rosenthal A., Birren B.W., Platzer M., Shimizu N.,
RA   Lander E.S.;
RT   "DNA sequence and analysis of human chromosome 8.";
RL   Nature 439:331-335(2006).
RN   [2] {ECO:0000313|Ensembl:ENSP00000430262}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JUL-2011) to UniProtKB.
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DR   EMBL; AC055822; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC100812; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; E5RG23; -.
DR   jPOST; E5RG23; -.
DR   PeptideAtlas; E5RG23; -.
DR   PRIDE; E5RG23; -.
DR   Ensembl; ENST00000523253; ENSP00000430262; ENSG00000205268.
DR   UCSC; uc064nih.1; human.
DR   EuPathDB; HostDB:ENSG00000205268.10; -.
DR   HGNC; HGNC:8791; PDE7A.
DR   OpenTargets; ENSG00000205268; -.
DR   eggNOG; KOG3689; Eukaryota.
DR   eggNOG; ENOG410XRI7; LUCA.
DR   GeneTree; ENSGT00940000157658; -.
DR   ChiTaRS; PDE7A; human.
DR   Proteomes; UP000005640; Chromosome 8.
DR   Bgee; ENSG00000205268; Expressed in 198 organ(s), highest expression level in secondary oocyte.
DR   ExpressionAtlas; E5RG23; baseline and differential.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Proteomics identification {ECO:0000213|PeptideAtlas:E5RG23};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     19       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        20     85       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5008413782.
FT   NON_TER      85     85       {ECO:0000313|Ensembl:ENSP00000430262}.
SQ   SEQUENCE   85 AA;  9857 MW;  6857E922F6444E01 CRC64;
     MGITLIWCLA LVLIKWITSK RRGAISYDSS DQTALYIRML GDVRVRSRAG FESERRGSHP
     YIDFRIFHSQ SEIEVSVSAR NIRRL
//