ID   E5RFJ9_HUMAN            Unreviewed;       147 AA.
AC   E5RFJ9;
DT   08-FEB-2011, integrated into UniProtKB/TrEMBL.
DT   08-FEB-2011, sequence version 1.
DT   16-JAN-2019, entry version 43.
DE   SubName: Full=Store-operated calcium entry-associated regulatory factor {ECO:0000313|Ensembl:ENSP00000428832};
DE   Flags: Fragment;
GN   Name=SARAF {ECO:0000313|Ensembl:ENSP00000428832};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000428832, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000428832, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16421571; DOI=10.1038/nature04406;
RA   Nusbaum C., Mikkelsen T.S., Zody M.C., Asakawa S., Taudien S.,
RA   Garber M., Kodira C.D., Schueler M.G., Shimizu A., Whittaker C.A.,
RA   Chang J.L., Cuomo C.A., Dewar K., FitzGerald M.G., Yang X.,
RA   Allen N.R., Anderson S., Asakawa T., Blechschmidt K., Bloom T.,
RA   Borowsky M.L., Butler J., Cook A., Corum B., DeArellano K.,
RA   DeCaprio D., Dooley K.T., Dorris L. III, Engels R., Glockner G.,
RA   Hafez N., Hagopian D.S., Hall J.L., Ishikawa S.K., Jaffe D.B.,
RA   Kamat A., Kudoh J., Lehmann R., Lokitsang T., Macdonald P.,
RA   Major J.E., Matthews C.D., Mauceli E., Menzel U., Mihalev A.H.,
RA   Minoshima S., Murayama Y., Naylor J.W., Nicol R., Nguyen C.,
RA   O'Leary S.B., O'Neill K., Parker S.C., Polley A., Raymond C.K.,
RA   Reichwald K., Rodriguez J., Sasaki T., Schilhabel M., Siddiqui R.,
RA   Smith C.L., Sneddon T.P., Talamas J.A., Tenzin P., Topham K.,
RA   Venkataraman V., Wen G., Yamazaki S., Young S.K., Zeng Q.,
RA   Zimmer A.R., Rosenthal A., Birren B.W., Platzer M., Shimizu N.,
RA   Lander E.S.;
RT   "DNA sequence and analysis of human chromosome 8.";
RL   Nature 439:331-335(2006).
RN   [2] {ECO:0000313|Ensembl:ENSP00000428832}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JUL-2011) to UniProtKB.
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DR   EMBL; AC044849; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; E5RFJ9; -.
DR   jPOST; E5RFJ9; -.
DR   MaxQB; E5RFJ9; -.
DR   PeptideAtlas; E5RFJ9; -.
DR   PRIDE; E5RFJ9; -.
DR   Ensembl; ENST00000523761; ENSP00000428832; ENSG00000133872.
DR   UCSC; uc064lrq.1; human.
DR   EuPathDB; HostDB:ENSG00000133872.13; -.
DR   HGNC; HGNC:28789; SARAF.
DR   OpenTargets; ENSG00000133872; -.
DR   GeneTree; ENSGT00390000013419; -.
DR   ChiTaRS; SARAF; human.
DR   Proteomes; UP000005640; Chromosome 8.
DR   Bgee; ENSG00000133872; Expressed in 239 organ(s), highest expression level in frontal cortex.
DR   ExpressionAtlas; E5RFJ9; baseline and differential.
DR   GO; GO:0030176; C:integral component of endoplasmic reticulum membrane; IEA:InterPro.
DR   GO; GO:2001256; P:regulation of store-operated calcium entry; IEA:InterPro.
DR   InterPro; IPR009567; SARAF.
DR   PANTHER; PTHR15929; PTHR15929; 1.
DR   Pfam; PF06682; SARAF; 1.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Proteomics identification {ECO:0000213|MaxQB:E5RFJ9,
KW   ECO:0000213|PeptideAtlas:E5RFJ9};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     30       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        31    147       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5003198311.
FT   NON_TER     147    147       {ECO:0000313|Ensembl:ENSP00000428832}.
SQ   SEQUENCE   147 AA;  16085 MW;  24E2A74D844B9EC9 CRC64;
     MAAACGPGAA GYCLLLGLHL FLLTAGPALG WNDPALTLHY DRYTTSRRLD PIPQLKCVGG
     TAGCDSYTPK VIQCQNKGWD GYDVQWECKT DLDIAYKFGK TVVSCEGYES SEDQYVLRGS
     CGLEYNLDYT ELGLQKLKES GKQHGFA
//