ID   E3W988_HUMAN            Unreviewed;       155 AA.
AC   E3W988;
DT   11-JAN-2011, integrated into UniProtKB/TrEMBL.
DT   08-FEB-2011, sequence version 2.
DT   05-DEC-2018, entry version 60.
DE   SubName: Full=Disintegrin and metalloproteinase domain-containing protein 32 {ECO:0000313|Ensembl:ENSP00000382727};
DE   Flags: Fragment;
GN   Name=ADAM32 {ECO:0000313|Ensembl:ENSP00000382727};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000382727, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000213|PubMed:17081983}
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX   PubMed=17081983; DOI=10.1016/j.cell.2006.09.026;
RA   Olsen J.V., Blagoev B., Gnad F., Macek B., Kumar C., Mortensen P.,
RA   Mann M.;
RT   "Global, in vivo, and site-specific phosphorylation dynamics in
RT   signaling networks.";
RL   Cell 127:635-648(2006).
RN   [2] {ECO:0000313|Ensembl:ENSP00000382727, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16421571; DOI=10.1038/nature04406;
RA   Nusbaum C., Mikkelsen T.S., Zody M.C., Asakawa S., Taudien S.,
RA   Garber M., Kodira C.D., Schueler M.G., Shimizu A., Whittaker C.A.,
RA   Chang J.L., Cuomo C.A., Dewar K., FitzGerald M.G., Yang X.,
RA   Allen N.R., Anderson S., Asakawa T., Blechschmidt K., Bloom T.,
RA   Borowsky M.L., Butler J., Cook A., Corum B., DeArellano K.,
RA   DeCaprio D., Dooley K.T., Dorris L. III, Engels R., Glockner G.,
RA   Hafez N., Hagopian D.S., Hall J.L., Ishikawa S.K., Jaffe D.B.,
RA   Kamat A., Kudoh J., Lehmann R., Lokitsang T., Macdonald P.,
RA   Major J.E., Matthews C.D., Mauceli E., Menzel U., Mihalev A.H.,
RA   Minoshima S., Murayama Y., Naylor J.W., Nicol R., Nguyen C.,
RA   O'Leary S.B., O'Neill K., Parker S.C., Polley A., Raymond C.K.,
RA   Reichwald K., Rodriguez J., Sasaki T., Schilhabel M., Siddiqui R.,
RA   Smith C.L., Sneddon T.P., Talamas J.A., Tenzin P., Topham K.,
RA   Venkataraman V., Wen G., Yamazaki S., Young S.K., Zeng Q.,
RA   Zimmer A.R., Rosenthal A., Birren B.W., Platzer M., Shimizu N.,
RA   Lander E.S.;
RT   "DNA sequence and analysis of human chromosome 8.";
RL   Nature 439:331-335(2006).
RN   [3] {ECO:0000213|PubMed:20068231}
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX   PubMed=20068231; DOI=10.1126/scisignal.2000475;
RA   Olsen J.V., Vermeulen M., Santamaria A., Kumar C., Miller M.L.,
RA   Jensen L.J., Gnad F., Cox J., Jensen T.S., Nigg E.A., Brunak S.,
RA   Mann M.;
RT   "Quantitative phosphoproteomics reveals widespread full
RT   phosphorylation site occupancy during mitosis.";
RL   Sci. Signal. 3:ra3-RA3(2010).
RN   [4] {ECO:0000313|Ensembl:ENSP00000382727}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JUL-2011) to UniProtKB.
RN   [5] {ECO:0000313|Ensembl:ENSP00000487692}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (AUG-2015) to UniProtKB.
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DR   EMBL; AC105091; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC105185; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC245594; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   PRIDE; E3W988; -.
DR   Ensembl; ENST00000399831; ENSP00000382727; ENSG00000197140.
DR   Ensembl; ENST00000633822; ENSP00000487692; ENSG00000275594.
DR   UCSC; uc064mfe.1; human.
DR   EuPathDB; HostDB:ENSG00000197140.14; -.
DR   HGNC; HGNC:15479; ADAM32.
DR   OpenTargets; ENSG00000197140; -.
DR   GeneTree; ENSGT00940000161015; -.
DR   ChiTaRS; ADAM32; human.
DR   Proteomes; UP000005640; Chromosome 8.
DR   Bgee; ENSG00000197140; Expressed in 106 organ(s), highest expression level in testis.
DR   ExpressionAtlas; E3W988; baseline and differential.
DR   InterPro; IPR002870; Peptidase_M12B_N.
DR   Pfam; PF01562; Pep_M12B_propep; 1.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Proteomics identification {ECO:0000213|PeptideAtlas:E3W988};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     16       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        17    155       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5014570846.
FT   DOMAIN       39    119       Pep_M12B_propep.
FT                                {ECO:0000259|Pfam:PF01562}.
FT   NON_TER     155    155       {ECO:0000313|Ensembl:ENSP00000382727}.
SQ   SEQUENCE   155 AA;  17884 MW;  61B5B336C61E80A8 CRC64;
     MFRLWLLLAG LCGLLASRPG FQNSLLQIVI PEKIQTNTND SSEIEYEQIS YIIPIDEKLY
     TVHLKQRYFL ADNFMIYLYN QGSMNTYSSD IQTQCYYQGN IEGYPDSMVT LSTCSGLRSL
     KEQPMDDNIF ISEKSEPAVP DLFPLYLEMH IVVDK
//