ID   D6RGJ9_HUMAN            Unreviewed;       148 AA.
AC   D6RGJ9;
DT   13-JUL-2010, integrated into UniProtKB/TrEMBL.
DT   05-OCT-2016, sequence version 8.
DT   16-JAN-2019, entry version 49.
DE   SubName: Full=Transmembrane protein 108 {ECO:0000313|Ensembl:ENSP00000426301};
DE   Flags: Fragment;
GN   Name=TMEM108 {ECO:0000313|Ensembl:ENSP00000426301};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000426301, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000426301, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16641997; DOI=10.1038/nature04728;
RA   Muzny D.M., Scherer S.E., Kaul R., Wang J., Yu J., Sudbrak R.,
RA   Buhay C.J., Chen R., Cree A., Ding Y., Dugan-Rocha S., Gill R.,
RA   Gunaratne P., Harris R.A., Hawes A.C., Hernandez J., Hodgson A.V.,
RA   Hume J., Jackson A., Khan Z.M., Kovar-Smith C., Lewis L.R.,
RA   Lozado R.J., Metzker M.L., Milosavljevic A., Miner G.R., Morgan M.B.,
RA   Nazareth L.V., Scott G., Sodergren E., Song X.Z., Steffen D., Wei S.,
RA   Wheeler D.A., Wright M.W., Worley K.C., Yuan Y., Zhang Z., Adams C.Q.,
RA   Ansari-Lari M.A., Ayele M., Brown M.J., Chen G., Chen Z.,
RA   Clendenning J., Clerc-Blankenburg K.P., Chen R., Chen Z., Davis C.,
RA   Delgado O., Dinh H.H., Dong W., Draper H., Ernst S., Fu G.,
RA   Gonzalez-Garay M.L., Garcia D.K., Gillett W., Gu J., Hao B.,
RA   Haugen E., Havlak P., He X., Hennig S., Hu S., Huang W., Jackson L.R.,
RA   Jacob L.S., Kelly S.H., Kube M., Levy R., Li Z., Liu B., Liu J.,
RA   Liu W., Lu J., Maheshwari M., Nguyen B.V., Okwuonu G.O., Palmeiri A.,
RA   Pasternak S., Perez L.M., Phelps K.A., Plopper F.J., Qiang B.,
RA   Raymond C., Rodriguez R., Saenphimmachak C., Santibanez J., Shen H.,
RA   Shen Y., Subramanian S., Tabor P.E., Verduzco D., Waldron L., Wang J.,
RA   Wang J., Wang Q., Williams G.A., Wong G.K., Yao Z., Zhang J.,
RA   Zhang X., Zhao G., Zhou J., Zhou Y., Nelson D., Lehrach H.,
RA   Reinhardt R., Naylor S.L., Yang H., Olson M., Weinstock G.,
RA   Gibbs R.A.;
RT   "The DNA sequence, annotation and analysis of human chromosome 3.";
RL   Nature 440:1194-1198(2006).
RN   [2] {ECO:0000313|Ensembl:ENSP00000426301}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JUL-2011) to UniProtKB.
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DR   EMBL; AC018472; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC055753; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC079942; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC092984; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; D6RGJ9; -.
DR   jPOST; D6RGJ9; -.
DR   PRIDE; D6RGJ9; -.
DR   Ensembl; ENST00000512137; ENSP00000426301; ENSG00000144868.
DR   UCSC; uc062nyn.1; human.
DR   EuPathDB; HostDB:ENSG00000144868.13; -.
DR   HGNC; HGNC:28451; TMEM108.
DR   OpenTargets; ENSG00000144868; -.
DR   eggNOG; ENOG410IEMG; Eukaryota.
DR   eggNOG; ENOG410YCMK; LUCA.
DR   GeneTree; ENSGT00390000000626; -.
DR   ChiTaRS; TMEM108; human.
DR   Proteomes; UP000005640; Chromosome 3.
DR   Bgee; ENSG00000144868; Expressed in 154 organ(s), highest expression level in frontal cortex.
DR   ExpressionAtlas; D6RGJ9; baseline and differential.
DR   InterPro; IPR031508; TMEM108.
DR   PANTHER; PTHR28673; PTHR28673; 1.
DR   Pfam; PF15759; TMEM108; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     26       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        27    148       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5008413431.
FT   NON_TER     148    148       {ECO:0000313|Ensembl:ENSP00000426301}.
SQ   SEQUENCE   148 AA;  15199 MW;  5799F1D771E5F7D6 CRC64;
     MKRSLQALYC QLLSFLLILA LTEALAFAIQ EPSPRESLQV LPSGTPPGTM VTAPHSSTRH
     TSVVMLTPNP DGPPSQAAAP MATPTPRAEG HPPTHTISTI AATVTAPHSE SSLSTGPAPA
     AMATTSSKPE GRPRGQAAPT ILLTKPPG
//