ID   D6RFL4_HUMAN            Unreviewed;       213 AA.
AC   D6RFL4;
DT   13-JUL-2010, integrated into UniProtKB/TrEMBL.
DT   13-JUL-2010, sequence version 1.
DT   16-JAN-2019, entry version 53.
DE   SubName: Full=Monocyte differentiation antigen CD14 {ECO:0000313|Ensembl:ENSP00000426543};
DE   Flags: Fragment;
GN   Name=CD14 {ECO:0000313|Ensembl:ENSP00000426543};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000426543, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000426543, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15372022; DOI=10.1038/nature02919;
RA   Schmutz J., Martin J., Terry A., Couronne O., Grimwood J., Lowry S.,
RA   Gordon L.A., Scott D., Xie G., Huang W., Hellsten U., Tran-Gyamfi M.,
RA   She X., Prabhakar S., Aerts A., Altherr M., Bajorek E., Black S.,
RA   Branscomb E., Caoile C., Challacombe J.F., Chan Y.M., Denys M.,
RA   Detter J.C., Escobar J., Flowers D., Fotopulos D., Glavina T.,
RA   Gomez M., Gonzales E., Goodstein D., Grigoriev I., Groza M.,
RA   Hammon N., Hawkins T., Haydu L., Israni S., Jett J., Kadner K.,
RA   Kimball H., Kobayashi A., Lopez F., Lou Y., Martinez D., Medina C.,
RA   Morgan J., Nandkeshwar R., Noonan J.P., Pitluck S., Pollard M.,
RA   Predki P., Priest J., Ramirez L., Retterer J., Rodriguez A.,
RA   Rogers S., Salamov A., Salazar A., Thayer N., Tice H., Tsai M.,
RA   Ustaszewska A., Vo N., Wheeler J., Wu K., Yang J., Dickson M.,
RA   Cheng J.-F., Eichler E.E., Olsen A., Pennacchio L.A., Rokhsar D.S.,
RA   Richardson P., Lucas S.M., Myers R.M., Rubin E.M.;
RT   "The DNA sequence and comparative analysis of human chromosome 5.";
RL   Nature 431:268-274(2004).
RN   [2] {ECO:0000313|Ensembl:ENSP00000426543}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JUL-2011) to UniProtKB.
RN   [3] {ECO:0000213|PubMed:24275569}
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX   PubMed=24275569; DOI=10.1016/j.jprot.2013.11.014;
RA   Bian Y., Song C., Cheng K., Dong M., Wang F., Huang J., Sun D.,
RA   Wang L., Ye M., Zou H.;
RT   "An enzyme assisted RP-RPLC approach for in-depth analysis of human
RT   liver phosphoproteome.";
RL   J. Proteomics 96:253-262(2014).
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DR   EMBL; AC116353; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; D6RFL4; -.
DR   jPOST; D6RFL4; -.
DR   PeptideAtlas; D6RFL4; -.
DR   PRIDE; D6RFL4; -.
DR   Ensembl; ENST00000498971; ENSP00000426543; ENSG00000170458.
DR   UCSC; uc063hwn.1; human.
DR   EuPathDB; HostDB:ENSG00000170458.13; -.
DR   HGNC; HGNC:1628; CD14.
DR   OpenTargets; ENSG00000170458; -.
DR   eggNOG; ENOG410IXG9; Eukaryota.
DR   eggNOG; ENOG41118N2; LUCA.
DR   GeneTree; ENSGT00390000005689; -.
DR   HOGENOM; HOG000237268; -.
DR   ChiTaRS; CD14; human.
DR   Proteomes; UP000005640; Chromosome 5.
DR   Bgee; ENSG00000170458; Expressed in 214 organ(s), highest expression level in liver.
DR   ExpressionAtlas; D6RFL4; baseline and differential.
DR   Gene3D; 3.80.10.10; -; 1.
DR   InterPro; IPR032675; LRR_dom_sf.
DR   InterPro; IPR016337; Monocyte_diff_Ag_CD14.
DR   PANTHER; PTHR10630; PTHR10630; 1.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Proteomics identification {ECO:0000213|MaxQB:D6RFL4,
KW   ECO:0000213|PeptideAtlas:D6RFL4};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     19       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        20    213       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5003087424.
FT   NON_TER     213    213       {ECO:0000313|Ensembl:ENSP00000426543}.
SQ   SEQUENCE   213 AA;  23313 MW;  57C828B65C1A1CCF CRC64;
     MERASCLLLL LLPLVHVSAT TPEPCELDDE DFRCVCNFSE PQPDWSEAFQ CVSAVEVEIH
     AGGLNLEPFL KRVDADADPR QYADTVKALR VRRLTVGAAQ VPAQLLVGAL RVLAYSRLKE
     LTLEDLKITG TMPPLPLEAT GLALSSLRLR NVSWATGRSW LAELQQWLKP GLKVLSIAQA
     HSPAFSCEQV RAFPALTSLD LSDNPGLGER GLM
//