ID   D6RFH6_HUMAN            Unreviewed;       153 AA.
AC   D6RFH6;
DT   13-JUL-2010, integrated into UniProtKB/TrEMBL.
DT   13-JUL-2010, sequence version 1.
DT   16-JAN-2019, entry version 39.
DE   SubName: Full=Transmembrane protein 108 {ECO:0000313|Ensembl:ENSP00000421486};
DE   Flags: Fragment;
GN   Name=TMEM108 {ECO:0000313|Ensembl:ENSP00000421486};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000421486, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000421486, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16641997; DOI=10.1038/nature04728;
RA   Muzny D.M., Scherer S.E., Kaul R., Wang J., Yu J., Sudbrak R.,
RA   Buhay C.J., Chen R., Cree A., Ding Y., Dugan-Rocha S., Gill R.,
RA   Gunaratne P., Harris R.A., Hawes A.C., Hernandez J., Hodgson A.V.,
RA   Hume J., Jackson A., Khan Z.M., Kovar-Smith C., Lewis L.R.,
RA   Lozado R.J., Metzker M.L., Milosavljevic A., Miner G.R., Morgan M.B.,
RA   Nazareth L.V., Scott G., Sodergren E., Song X.Z., Steffen D., Wei S.,
RA   Wheeler D.A., Wright M.W., Worley K.C., Yuan Y., Zhang Z., Adams C.Q.,
RA   Ansari-Lari M.A., Ayele M., Brown M.J., Chen G., Chen Z.,
RA   Clendenning J., Clerc-Blankenburg K.P., Chen R., Chen Z., Davis C.,
RA   Delgado O., Dinh H.H., Dong W., Draper H., Ernst S., Fu G.,
RA   Gonzalez-Garay M.L., Garcia D.K., Gillett W., Gu J., Hao B.,
RA   Haugen E., Havlak P., He X., Hennig S., Hu S., Huang W., Jackson L.R.,
RA   Jacob L.S., Kelly S.H., Kube M., Levy R., Li Z., Liu B., Liu J.,
RA   Liu W., Lu J., Maheshwari M., Nguyen B.V., Okwuonu G.O., Palmeiri A.,
RA   Pasternak S., Perez L.M., Phelps K.A., Plopper F.J., Qiang B.,
RA   Raymond C., Rodriguez R., Saenphimmachak C., Santibanez J., Shen H.,
RA   Shen Y., Subramanian S., Tabor P.E., Verduzco D., Waldron L., Wang J.,
RA   Wang J., Wang Q., Williams G.A., Wong G.K., Yao Z., Zhang J.,
RA   Zhang X., Zhao G., Zhou J., Zhou Y., Nelson D., Lehrach H.,
RA   Reinhardt R., Naylor S.L., Yang H., Olson M., Weinstock G.,
RA   Gibbs R.A.;
RT   "The DNA sequence, annotation and analysis of human chromosome 3.";
RL   Nature 440:1194-1198(2006).
RN   [2] {ECO:0000313|Ensembl:ENSP00000421486}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JUL-2011) to UniProtKB.
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DR   EMBL; AC018472; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC055753; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC079942; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC092984; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; D6RFH6; -.
DR   jPOST; D6RFH6; -.
DR   PRIDE; D6RFH6; -.
DR   Ensembl; ENST00000510183; ENSP00000421486; ENSG00000144868.
DR   UCSC; uc062nyp.1; human.
DR   EuPathDB; HostDB:ENSG00000144868.13; -.
DR   HGNC; HGNC:28451; TMEM108.
DR   OpenTargets; ENSG00000144868; -.
DR   eggNOG; ENOG410IEMG; Eukaryota.
DR   eggNOG; ENOG410YCMK; LUCA.
DR   GeneTree; ENSGT00390000000626; -.
DR   HOGENOM; HOG000154603; -.
DR   ChiTaRS; TMEM108; human.
DR   Proteomes; UP000005640; Chromosome 3.
DR   Bgee; ENSG00000144868; Expressed in 154 organ(s), highest expression level in frontal cortex.
DR   ExpressionAtlas; D6RFH6; baseline and differential.
DR   InterPro; IPR031508; TMEM108.
DR   PANTHER; PTHR28673; PTHR28673; 1.
DR   Pfam; PF15759; TMEM108; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     26       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        27    153       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5003087573.
FT   NON_TER     153    153       {ECO:0000313|Ensembl:ENSP00000421486}.
SQ   SEQUENCE   153 AA;  15712 MW;  DC24204C174799F1 CRC64;
     MKRSLQALYC QLLSFLLILA LTEALAFAIQ EPSPRESLQV LPSGTPPGTM VTAPHSSTRH
     TSVVMLTPNP DGPPSQAAAP MATPTPRAEG HPPTHTISTI AATVTAPHSE SSLSTGPAPA
     AMATTSSKPE GRPRGQAAPT ILLTKPPGAT SRP
//