ID   D6RDX7_HUMAN            Unreviewed;       273 AA.
AC   D6RDX7;
DT   13-JUL-2010, integrated into UniProtKB/TrEMBL.
DT   13-JUL-2010, sequence version 1.
DT   16-JAN-2019, entry version 55.
DE   SubName: Full=Embigin {ECO:0000313|Ensembl:ENSP00000425215};
GN   Name=EMB {ECO:0000313|Ensembl:ENSP00000425215};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000425215, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000425215, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15372022; DOI=10.1038/nature02919;
RA   Schmutz J., Martin J., Terry A., Couronne O., Grimwood J., Lowry S.,
RA   Gordon L.A., Scott D., Xie G., Huang W., Hellsten U., Tran-Gyamfi M.,
RA   She X., Prabhakar S., Aerts A., Altherr M., Bajorek E., Black S.,
RA   Branscomb E., Caoile C., Challacombe J.F., Chan Y.M., Denys M.,
RA   Detter J.C., Escobar J., Flowers D., Fotopulos D., Glavina T.,
RA   Gomez M., Gonzales E., Goodstein D., Grigoriev I., Groza M.,
RA   Hammon N., Hawkins T., Haydu L., Israni S., Jett J., Kadner K.,
RA   Kimball H., Kobayashi A., Lopez F., Lou Y., Martinez D., Medina C.,
RA   Morgan J., Nandkeshwar R., Noonan J.P., Pitluck S., Pollard M.,
RA   Predki P., Priest J., Ramirez L., Retterer J., Rodriguez A.,
RA   Rogers S., Salamov A., Salazar A., Thayer N., Tice H., Tsai M.,
RA   Ustaszewska A., Vo N., Wheeler J., Wu K., Yang J., Dickson M.,
RA   Cheng J.-F., Eichler E.E., Olsen A., Pennacchio L.A., Rokhsar D.S.,
RA   Richardson P., Lucas S.M., Myers R.M., Rubin E.M.;
RT   "The DNA sequence and comparative analysis of human chromosome 5.";
RL   Nature 431:268-274(2004).
RN   [2] {ECO:0000313|Ensembl:ENSP00000425215}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JUL-2011) to UniProtKB.
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DR   EMBL; AC035145; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC091833; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; D6RDX7; -.
DR   jPOST; D6RDX7; -.
DR   MaxQB; D6RDX7; -.
DR   PeptideAtlas; D6RDX7; -.
DR   PRIDE; D6RDX7; -.
DR   Ensembl; ENST00000508934; ENSP00000425215; ENSG00000170571.
DR   UCSC; uc063dlf.1; human.
DR   EuPathDB; HostDB:ENSG00000170571.11; -.
DR   HGNC; HGNC:30465; EMB.
DR   OpenTargets; ENSG00000170571; -.
DR   GeneTree; ENSGT00940000158944; -.
DR   HOGENOM; HOG000082417; -.
DR   ChiTaRS; EMB; human.
DR   Proteomes; UP000005640; Chromosome 5.
DR   Bgee; ENSG00000170571; Expressed in 103 organ(s), highest expression level in leukocyte.
DR   ExpressionAtlas; D6RDX7; baseline and differential.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.40.10; -; 1.
DR   InterPro; IPR027114; Embigin.
DR   InterPro; IPR007110; Ig-like_dom.
DR   InterPro; IPR036179; Ig-like_dom_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR013098; Ig_I-set.
DR   InterPro; IPR003599; Ig_sub.
DR   PANTHER; PTHR10075:SF4; PTHR10075:SF4; 2.
DR   Pfam; PF07679; I-set; 1.
DR   SMART; SM00409; IG; 1.
DR   SUPFAM; SSF48726; SSF48726; 1.
DR   PROSITE; PS50835; IG_LIKE; 1.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Proteomics identification {ECO:0000213|EPD:D6RDX7,
KW   ECO:0000213|MaxQB:D6RDX7, ECO:0000213|PeptideAtlas:D6RDX7};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   SIGNAL        1     32       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        33    273       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5003087550.
FT   TRANSMEM    210    227       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN      105    185       Ig-like. {ECO:0000259|PROSITE:PS50835}.
SQ   SEQUENCE   273 AA;  30874 MW;  507F3C77F5B0AC98 CRC64;
     MRALPGLLEA RARTPRLLLL QCLLAAARPS SADGSAPDSP FTSPPLREEI MANNFSLESH
     NISLTGSTLY TQYRFTIINS KQMGSYSCFF REEKEQRGTF NFKVPELHGK NKPLISYVGD
     STVLTCKCQN CFPLNWTWYS SNGSVKVPVG VQMNKYVING TYANETKLKI TQLLEEDGES
     YWCRALFQLG ESEEHIELVV LSYLVPLKPF LVIVAEVILL VATILLCEKY TQKKKKHSDE
     GKEFEQIEQL KSDDSNGIEN NVPRHRKNES LGQ
//