ID   D6RC59_HUMAN            Unreviewed;       153 AA.
AC   D6RC59;
DT   13-JUL-2010, integrated into UniProtKB/TrEMBL.
DT   13-JUL-2010, sequence version 1.
DT   16-JAN-2019, entry version 58.
DE   SubName: Full=Hyaluronan and proteoglycan link protein 1 {ECO:0000313|Ensembl:ENSP00000423836};
DE   Flags: Fragment;
GN   Name=HAPLN1 {ECO:0000313|Ensembl:ENSP00000423836};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000423836, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000423836, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15372022; DOI=10.1038/nature02919;
RA   Schmutz J., Martin J., Terry A., Couronne O., Grimwood J., Lowry S.,
RA   Gordon L.A., Scott D., Xie G., Huang W., Hellsten U., Tran-Gyamfi M.,
RA   She X., Prabhakar S., Aerts A., Altherr M., Bajorek E., Black S.,
RA   Branscomb E., Caoile C., Challacombe J.F., Chan Y.M., Denys M.,
RA   Detter J.C., Escobar J., Flowers D., Fotopulos D., Glavina T.,
RA   Gomez M., Gonzales E., Goodstein D., Grigoriev I., Groza M.,
RA   Hammon N., Hawkins T., Haydu L., Israni S., Jett J., Kadner K.,
RA   Kimball H., Kobayashi A., Lopez F., Lou Y., Martinez D., Medina C.,
RA   Morgan J., Nandkeshwar R., Noonan J.P., Pitluck S., Pollard M.,
RA   Predki P., Priest J., Ramirez L., Retterer J., Rodriguez A.,
RA   Rogers S., Salamov A., Salazar A., Thayer N., Tice H., Tsai M.,
RA   Ustaszewska A., Vo N., Wheeler J., Wu K., Yang J., Dickson M.,
RA   Cheng J.-F., Eichler E.E., Olsen A., Pennacchio L.A., Rokhsar D.S.,
RA   Richardson P., Lucas S.M., Myers R.M., Rubin E.M.;
RT   "The DNA sequence and comparative analysis of human chromosome 5.";
RL   Nature 431:268-274(2004).
RN   [2] {ECO:0000313|Ensembl:ENSP00000423836}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JUL-2011) to UniProtKB.
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DR   EMBL; AC020899; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; KC877031; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; D6RC59; -.
DR   jPOST; D6RC59; -.
DR   PeptideAtlas; D6RC59; -.
DR   PRIDE; D6RC59; -.
DR   Ensembl; ENST00000515590; ENSP00000423836; ENSG00000145681.
DR   UCSC; uc063fcg.1; human.
DR   EuPathDB; HostDB:ENSG00000145681.10; -.
DR   HGNC; HGNC:2380; HAPLN1.
DR   OpenTargets; ENSG00000145681; -.
DR   eggNOG; ENOG410IF28; Eukaryota.
DR   eggNOG; ENOG410XRS8; LUCA.
DR   GeneTree; ENSGT00940000159267; -.
DR   HOGENOM; HOG000010279; -.
DR   ChiTaRS; HAPLN1; human.
DR   Proteomes; UP000005640; Chromosome 5.
DR   Bgee; ENSG00000145681; Expressed in 133 organ(s), highest expression level in tibia.
DR   ExpressionAtlas; D6RC59; baseline and differential.
DR   Gene3D; 2.60.40.10; -; 1.
DR   InterPro; IPR007110; Ig-like_dom.
DR   InterPro; IPR036179; Ig-like_dom_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR003599; Ig_sub.
DR   InterPro; IPR013106; Ig_V-set.
DR   Pfam; PF07686; V-set; 1.
DR   SMART; SM00409; IG; 1.
DR   SMART; SM00406; IGv; 1.
DR   SUPFAM; SSF48726; SSF48726; 1.
DR   PROSITE; PS50835; IG_LIKE; 1.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Proteomics identification {ECO:0000213|EPD:D6RC59,
KW   ECO:0000213|MaxQB:D6RC59, ECO:0000213|PeptideAtlas:D6RC59};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     15       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        16    153       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5012474781.
FT   DOMAIN       38    152       Ig-like. {ECO:0000259|PROSITE:PS50835}.
FT   NON_TER     153    153       {ECO:0000313|Ensembl:ENSP00000423836}.
SQ   SEQUENCE   153 AA;  17180 MW;  3824C4EA804EA967 CRC64;
     MKSLLLLVLI SICWADHLSD NYTLDHDRAI HIQAENGPHL LVEAEQAKVF SHRGGNVTLP
     CKFYRDPTAF GSGIHKIRIK WTKLTSDYLK EVDVFVSMGY HKKTYGGYQG RVFLKGGSDS
     DASLVITDLT LEDYGRYKCE VIEGLEDDTV VVA
//