ID   D6RBY3_HUMAN            Unreviewed;        61 AA.
AC   D6RBY3;
DT   13-JUL-2010, integrated into UniProtKB/TrEMBL.
DT   13-JUL-2010, sequence version 1.
DT   05-DEC-2018, entry version 53.
DE   SubName: Full=Spondin-2 {ECO:0000313|Ensembl:ENSP00000422516};
DE   Flags: Fragment;
GN   Name=SPON2 {ECO:0000313|Ensembl:ENSP00000422516};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000422516, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000422516, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15815621; DOI=10.1038/nature03466;
RA   Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H.,
RA   Minx P., Wagner-McPherson C., Layman D., Wylie K., Sekhon M.,
RA   Becker M.C., Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E.,
RA   Kremitzki C., Oddy L., Du H., Sun H., Bradshaw-Cordum H., Ali J.,
RA   Carter J., Cordes M., Harris A., Isak A., van Brunt A., Nguyen C.,
RA   Du F., Courtney L., Kalicki J., Ozersky P., Abbott S., Armstrong J.,
RA   Belter E.A., Caruso L., Cedroni M., Cotton M., Davidson T., Desai A.,
RA   Elliott G., Erb T., Fronick C., Gaige T., Haakenson W., Haglund K.,
RA   Holmes A., Harkins R., Kim K., Kruchowski S.S., Strong C.M.,
RA   Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K.,
RA   McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C.,
RA   Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N.,
RA   Swearengen-Shahid S., Snider J., Strong J.T., Thompson J., Yoakum M.,
RA   Leonard S., Pearman C., Trani L., Radionenko M., Waligorski J.E.,
RA   Wang C., Rock S.M., Tin-Wollam A.-M., Maupin R., Latreille P.,
RA   Wendl M.C., Yang S.-P., Pohl C., Wallis J.W., Spieth J., Bieri T.A.,
RA   Berkowicz N., Nelson J.O., Osborne J., Ding L., Meyer R., Sabo A.,
RA   Shotland Y., Sinha P., Wohldmann P.E., Cook L.L., Hickenbotham M.T.,
RA   Eldred J., Williams D., Jones T.A., She X., Ciccarelli F.D.,
RA   Izaurralde E., Taylor J., Schmutz J., Myers R.M., Cox D.R., Huang X.,
RA   McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C.,
RA   Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S.,
RA   Miller W., Eichler E.E., Bork P., Suyama M., Torrents D.,
RA   Waterston R.H., Wilson R.K.;
RT   "Generation and annotation of the DNA sequences of human chromosomes 2
RT   and 4.";
RL   Nature 434:724-731(2005).
RN   [2] {ECO:0000313|Ensembl:ENSP00000422516}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JUL-2011) to UniProtKB.
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DR   EMBL; AC092535; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; D6RBY3; -.
DR   PeptideAtlas; D6RBY3; -.
DR   PRIDE; D6RBY3; -.
DR   Ensembl; ENST00000502483; ENSP00000422516; ENSG00000159674.
DR   UCSC; uc062ujl.1; human.
DR   EuPathDB; HostDB:ENSG00000159674.11; -.
DR   HGNC; HGNC:11253; SPON2.
DR   OpenTargets; ENSG00000159674; -.
DR   eggNOG; ENOG410IR0P; Eukaryota.
DR   eggNOG; ENOG410XX1S; LUCA.
DR   GeneTree; ENSGT00940000159900; -.
DR   ChiTaRS; SPON2; human.
DR   Proteomes; UP000005640; Chromosome 4.
DR   Bgee; ENSG00000159674; Expressed in 214 organ(s), highest expression level in decidua.
DR   ExpressionAtlas; D6RBY3; baseline and differential.
DR   Gene3D; 2.60.40.2130; -; 1.
DR   InterPro; IPR009465; Spondin_N.
DR   InterPro; IPR038678; Spondin_N_sf.
DR   Pfam; PF06468; Spond_N; 1.
DR   PROSITE; PS51020; SPONDIN; 1.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Proteomics identification {ECO:0000213|PeptideAtlas:D6RBY3};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     26       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        27     61       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5003087535.
FT   DOMAIN       31     61       Spondin. {ECO:0000259|PROSITE:PS51020}.
FT   NON_TER      61     61       {ECO:0000313|Ensembl:ENSP00000422516}.
SQ   SEQUENCE   61 AA;  6240 MW;  CFDA6764031124C2 CRC64;
     MENPSPAAAL GKALCALLLA TLGAAGQPLG GESICSARAL AKYSITFTGK WSQTAFPKQY
     P
//