ID   D6RAK7_HUMAN            Unreviewed;       161 AA.
AC   D6RAK7;
DT   13-JUL-2010, integrated into UniProtKB/TrEMBL.
DT   13-JUL-2010, sequence version 1.
DT   16-JAN-2019, entry version 58.
DE   SubName: Full=Hyaluronan and proteoglycan link protein 1 {ECO:0000313|Ensembl:ENSP00000421726};
GN   Name=HAPLN1 {ECO:0000313|Ensembl:ENSP00000421726};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000421726, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000421726, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15372022; DOI=10.1038/nature02919;
RA   Schmutz J., Martin J., Terry A., Couronne O., Grimwood J., Lowry S.,
RA   Gordon L.A., Scott D., Xie G., Huang W., Hellsten U., Tran-Gyamfi M.,
RA   She X., Prabhakar S., Aerts A., Altherr M., Bajorek E., Black S.,
RA   Branscomb E., Caoile C., Challacombe J.F., Chan Y.M., Denys M.,
RA   Detter J.C., Escobar J., Flowers D., Fotopulos D., Glavina T.,
RA   Gomez M., Gonzales E., Goodstein D., Grigoriev I., Groza M.,
RA   Hammon N., Hawkins T., Haydu L., Israni S., Jett J., Kadner K.,
RA   Kimball H., Kobayashi A., Lopez F., Lou Y., Martinez D., Medina C.,
RA   Morgan J., Nandkeshwar R., Noonan J.P., Pitluck S., Pollard M.,
RA   Predki P., Priest J., Ramirez L., Retterer J., Rodriguez A.,
RA   Rogers S., Salamov A., Salazar A., Thayer N., Tice H., Tsai M.,
RA   Ustaszewska A., Vo N., Wheeler J., Wu K., Yang J., Dickson M.,
RA   Cheng J.-F., Eichler E.E., Olsen A., Pennacchio L.A., Rokhsar D.S.,
RA   Richardson P., Lucas S.M., Myers R.M., Rubin E.M.;
RT   "The DNA sequence and comparative analysis of human chromosome 5.";
RL   Nature 431:268-274(2004).
RN   [2] {ECO:0000313|Ensembl:ENSP00000421726}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JUL-2011) to UniProtKB.
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DR   EMBL; AC020899; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; KC877031; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; D6RAK7; -.
DR   jPOST; D6RAK7; -.
DR   PeptideAtlas; D6RAK7; -.
DR   PRIDE; D6RAK7; -.
DR   Ensembl; ENST00000514416; ENSP00000421726; ENSG00000145681.
DR   UCSC; uc063fcf.1; human.
DR   EuPathDB; HostDB:ENSG00000145681.10; -.
DR   HGNC; HGNC:2380; HAPLN1.
DR   OpenTargets; ENSG00000145681; -.
DR   eggNOG; ENOG410IF28; Eukaryota.
DR   eggNOG; ENOG410XRS8; LUCA.
DR   GeneTree; ENSGT00940000159267; -.
DR   HOGENOM; HOG000010279; -.
DR   ChiTaRS; HAPLN1; human.
DR   Proteomes; UP000005640; Chromosome 5.
DR   Bgee; ENSG00000145681; Expressed in 133 organ(s), highest expression level in tibia.
DR   ExpressionAtlas; D6RAK7; baseline and differential.
DR   Gene3D; 2.60.40.10; -; 1.
DR   InterPro; IPR007110; Ig-like_dom.
DR   InterPro; IPR036179; Ig-like_dom_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR003599; Ig_sub.
DR   InterPro; IPR013106; Ig_V-set.
DR   Pfam; PF07686; V-set; 1.
DR   SMART; SM00409; IG; 1.
DR   SMART; SM00406; IGv; 1.
DR   SUPFAM; SSF48726; SSF48726; 1.
DR   PROSITE; PS50835; IG_LIKE; 1.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Proteomics identification {ECO:0000213|EPD:D6RAK7,
KW   ECO:0000213|MaxQB:D6RAK7, ECO:0000213|PeptideAtlas:D6RAK7};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     15       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        16    161       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5012203821.
FT   DOMAIN       38    152       Ig-like. {ECO:0000259|PROSITE:PS50835}.
SQ   SEQUENCE   161 AA;  18114 MW;  308B24D45EB3E8C9 CRC64;
     MKSLLLLVLI SICWADHLSD NYTLDHDRAI HIQAENGPHL LVEAEQAKVF SHRGGNVTLP
     CKFYRDPTAF GSGIHKIRIK WTKLTSDYLK EVDVFVSMGY HKKTYGGYQG RVFLKGGSDS
     DASLVITDLT LEDYGRYKCE VIEGLEDDTV VVALDLQGMY L
//