ID   D6RAG9_HUMAN            Unreviewed;       159 AA.
AC   D6RAG9;
DT   13-JUL-2010, integrated into UniProtKB/TrEMBL.
DT   13-JUL-2010, sequence version 1.
DT   16-JAN-2019, entry version 56.
DE   SubName: Full=Semaphorin-6A {ECO:0000313|Ensembl:ENSP00000421935};
DE   Flags: Fragment;
GN   Name=SEMA6A {ECO:0000313|Ensembl:ENSP00000421935};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000421935, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000421935, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15372022; DOI=10.1038/nature02919;
RA   Schmutz J., Martin J., Terry A., Couronne O., Grimwood J., Lowry S.,
RA   Gordon L.A., Scott D., Xie G., Huang W., Hellsten U., Tran-Gyamfi M.,
RA   She X., Prabhakar S., Aerts A., Altherr M., Bajorek E., Black S.,
RA   Branscomb E., Caoile C., Challacombe J.F., Chan Y.M., Denys M.,
RA   Detter J.C., Escobar J., Flowers D., Fotopulos D., Glavina T.,
RA   Gomez M., Gonzales E., Goodstein D., Grigoriev I., Groza M.,
RA   Hammon N., Hawkins T., Haydu L., Israni S., Jett J., Kadner K.,
RA   Kimball H., Kobayashi A., Lopez F., Lou Y., Martinez D., Medina C.,
RA   Morgan J., Nandkeshwar R., Noonan J.P., Pitluck S., Pollard M.,
RA   Predki P., Priest J., Ramirez L., Retterer J., Rodriguez A.,
RA   Rogers S., Salamov A., Salazar A., Thayer N., Tice H., Tsai M.,
RA   Ustaszewska A., Vo N., Wheeler J., Wu K., Yang J., Dickson M.,
RA   Cheng J.-F., Eichler E.E., Olsen A., Pennacchio L.A., Rokhsar D.S.,
RA   Richardson P., Lucas S.M., Myers R.M., Rubin E.M.;
RT   "The DNA sequence and comparative analysis of human chromosome 5.";
RL   Nature 431:268-274(2004).
RN   [2] {ECO:0000313|Ensembl:ENSP00000421935}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JUL-2011) to UniProtKB.
CC   -!- CAUTION: Lacks conserved residue(s) required for the propagation
CC       of feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00352}.
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DR   EMBL; AC008524; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC010296; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC027304; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; KC877077; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; D6RAG9; -.
DR   jPOST; D6RAG9; -.
DR   PeptideAtlas; D6RAG9; -.
DR   PRIDE; D6RAG9; -.
DR   Ensembl; ENST00000515009; ENSP00000421935; ENSG00000092421.
DR   UCSC; uc063gfr.1; human.
DR   EuPathDB; HostDB:ENSG00000092421.16; -.
DR   HGNC; HGNC:10738; SEMA6A.
DR   OpenTargets; ENSG00000092421; -.
DR   eggNOG; KOG3611; Eukaryota.
DR   eggNOG; ENOG410XQZC; LUCA.
DR   GeneTree; ENSGT00940000156565; -.
DR   HOGENOM; HOG000200291; -.
DR   ChiTaRS; SEMA6A; human.
DR   Proteomes; UP000005640; Chromosome 5.
DR   Bgee; ENSG00000092421; Expressed in 221 organ(s), highest expression level in adrenal cortex.
DR   ExpressionAtlas; D6RAG9; baseline and differential.
DR   Gene3D; 2.130.10.10; -; 1.
DR   InterPro; IPR001627; Semap_dom.
DR   InterPro; IPR036352; Semap_dom_sf.
DR   InterPro; IPR027231; Semaphorin.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   PANTHER; PTHR11036; PTHR11036; 1.
DR   Pfam; PF01403; Sema; 1.
DR   SUPFAM; SSF101912; SSF101912; 1.
DR   PROSITE; PS51004; SEMA; 1.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Proteomics identification {ECO:0000213|PeptideAtlas:D6RAG9};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     18       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        19    159       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5003087343.
FT   DOMAIN       24    159       Sema. {ECO:0000259|PROSITE:PS51004}.
FT   NON_TER     159    159       {ECO:0000313|Ensembl:ENSP00000421935}.
SQ   SEQUENCE   159 AA;  18357 MW;  1A62FC89C60496C6 CRC64;
     MRSEALLLYF TLLHFAGAGF PEDSEPISIS HGNYTKQYPV FVGHKPGRNT TQRHRLDIQM
     IMIMNGTLYI AARDHIYTVD IDTSHTEEIY CSKKLTWKSR QADVDTCRMK GKHKDECHNF
     IKVLLKKNDD ALFVCGTNAF NPSCRNYKMD TLEPFGDEF
//