ID   D6RA01_HUMAN            Unreviewed;        68 AA.
AC   D6RA01;
DT   13-JUL-2010, integrated into UniProtKB/TrEMBL.
DT   13-JUL-2010, sequence version 1.
DT   16-JAN-2019, entry version 44.
DE   SubName: Full=Beta-mannosidase {ECO:0000313|Ensembl:ENSP00000422001};
GN   Name=MANBA {ECO:0000313|Ensembl:ENSP00000422001};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000422001, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000422001, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15815621; DOI=10.1038/nature03466;
RA   Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H.,
RA   Minx P., Wagner-McPherson C., Layman D., Wylie K., Sekhon M.,
RA   Becker M.C., Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E.,
RA   Kremitzki C., Oddy L., Du H., Sun H., Bradshaw-Cordum H., Ali J.,
RA   Carter J., Cordes M., Harris A., Isak A., van Brunt A., Nguyen C.,
RA   Du F., Courtney L., Kalicki J., Ozersky P., Abbott S., Armstrong J.,
RA   Belter E.A., Caruso L., Cedroni M., Cotton M., Davidson T., Desai A.,
RA   Elliott G., Erb T., Fronick C., Gaige T., Haakenson W., Haglund K.,
RA   Holmes A., Harkins R., Kim K., Kruchowski S.S., Strong C.M.,
RA   Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K.,
RA   McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C.,
RA   Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N.,
RA   Swearengen-Shahid S., Snider J., Strong J.T., Thompson J., Yoakum M.,
RA   Leonard S., Pearman C., Trani L., Radionenko M., Waligorski J.E.,
RA   Wang C., Rock S.M., Tin-Wollam A.-M., Maupin R., Latreille P.,
RA   Wendl M.C., Yang S.-P., Pohl C., Wallis J.W., Spieth J., Bieri T.A.,
RA   Berkowicz N., Nelson J.O., Osborne J., Ding L., Meyer R., Sabo A.,
RA   Shotland Y., Sinha P., Wohldmann P.E., Cook L.L., Hickenbotham M.T.,
RA   Eldred J., Williams D., Jones T.A., She X., Ciccarelli F.D.,
RA   Izaurralde E., Taylor J., Schmutz J., Myers R.M., Cox D.R., Huang X.,
RA   McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C.,
RA   Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S.,
RA   Miller W., Eichler E.E., Bork P., Suyama M., Torrents D.,
RA   Waterston R.H., Wilson R.K.;
RT   "Generation and annotation of the DNA sequences of human chromosomes 2
RT   and 4.";
RL   Nature 434:724-731(2005).
RN   [2] {ECO:0000313|Ensembl:ENSP00000422001}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JUL-2011) to UniProtKB.
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DR   EMBL; AC018797; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AF213884; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; KF454940; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; D6RA01; -.
DR   jPOST; D6RA01; -.
DR   PeptideAtlas; D6RA01; -.
DR   Ensembl; ENST00000511813; ENSP00000422001; ENSG00000109323.
DR   UCSC; uc062yow.1; human.
DR   EuPathDB; HostDB:ENSG00000109323.8; -.
DR   HGNC; HGNC:6831; MANBA.
DR   OpenTargets; ENSG00000109323; -.
DR   eggNOG; KOG2230; Eukaryota.
DR   eggNOG; COG3250; LUCA.
DR   GeneTree; ENSGT00390000001670; -.
DR   ChiTaRS; MANBA; human.
DR   Proteomes; UP000005640; Chromosome 4.
DR   Bgee; ENSG00000109323; Expressed in 208 organ(s), highest expression level in leukocyte.
DR   ExpressionAtlas; D6RA01; baseline and differential.
DR   InterPro; IPR008979; Galactose-bd-like_sf.
DR   SUPFAM; SSF49785; SSF49785; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     19       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        20     68       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5003087301.
SQ   SEQUENCE   68 AA;  7134 MW;  03F480CB25B7BE71 CRC64;
     MRLHLLLLLA LCGAGTTAAE LSYSLRGNWS ICNGNGSLEL PGAVPGCVHS ALFQQGLIQS
     LTLSPRLE
//