ID   D6R9X8_HUMAN            Unreviewed;       142 AA.
AC   D6R9X8;
DT   13-JUL-2010, integrated into UniProtKB/TrEMBL.
DT   08-FEB-2011, sequence version 2.
DT   16-JAN-2019, entry version 56.
DE   SubName: Full=Integrin alpha-3 {ECO:0000313|Ensembl:ENSP00000422826};
GN   Name=ITGA3 {ECO:0000313|Ensembl:ENSP00000422826};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000422826, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000422826, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16625196; DOI=10.1038/nature04689;
RA   Zody M.C., Garber M., Adams D.J., Sharpe T., Harrow J., Lupski J.R.,
RA   Nicholson C., Searle S.M., Wilming L., Young S.K., Abouelleil A.,
RA   Allen N.R., Bi W., Bloom T., Borowsky M.L., Bugalter B.E., Butler J.,
RA   Chang J.L., Chen C.K., Cook A., Corum B., Cuomo C.A., de Jong P.J.,
RA   DeCaprio D., Dewar K., FitzGerald M., Gilbert J., Gibson R.,
RA   Gnerre S., Goldstein S., Grafham D.V., Grocock R., Hafez N.,
RA   Hagopian D.S., Hart E., Norman C.H., Humphray S., Jaffe D.B.,
RA   Jones M., Kamal M., Khodiyar V.K., LaButti K., Laird G., Lehoczky J.,
RA   Liu X., Lokyitsang T., Loveland J., Lui A., Macdonald P., Major J.E.,
RA   Matthews L., Mauceli E., McCarroll S.A., Mihalev A.H., Mudge J.,
RA   Nguyen C., Nicol R., O'Leary S.B., Osoegawa K., Schwartz D.C.,
RA   Shaw-Smith C., Stankiewicz P., Steward C., Swarbreck D.,
RA   Venkataraman V., Whittaker C.A., Yang X., Zimmer A.R., Bradley A.,
RA   Hubbard T., Birren B.W., Rogers J., Lander E.S., Nusbaum C.;
RT   "DNA sequence of human chromosome 17 and analysis of rearrangement in
RT   the human lineage.";
RL   Nature 440:1045-1049(2006).
RN   [2] {ECO:0000213|PubMed:21269460}
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX   PubMed=21269460; DOI=10.1186/1752-0509-5-17;
RA   Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P.,
RA   Burckstummer T., Bennett K.L., Superti-Furga G., Colinge J.;
RT   "Initial characterization of the human central proteome.";
RL   BMC Syst. Biol. 5:17-17(2011).
RN   [3] {ECO:0000313|Ensembl:ENSP00000422826}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JUL-2011) to UniProtKB.
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DR   EMBL; AC002401; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC009720; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; KF456287; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; D6R9X8; -.
DR   jPOST; D6R9X8; -.
DR   MaxQB; D6R9X8; -.
DR   PeptideAtlas; D6R9X8; -.
DR   PRIDE; D6R9X8; -.
DR   Ensembl; ENST00000506401; ENSP00000422826; ENSG00000005884.
DR   UCSC; uc060heg.1; human.
DR   EuPathDB; HostDB:ENSG00000005884.17; -.
DR   HGNC; HGNC:6139; ITGA3.
DR   OpenTargets; ENSG00000005884; -.
DR   eggNOG; ENOG410IPB6; Eukaryota.
DR   eggNOG; ENOG410ZZD8; LUCA.
DR   GeneTree; ENSGT00940000157746; -.
DR   ChiTaRS; ITGA3; human.
DR   Proteomes; UP000005640; Chromosome 17.
DR   Bgee; ENSG00000005884; Expressed in 99 organ(s), highest expression level in adult mammalian kidney.
DR   ExpressionAtlas; D6R9X8; baseline and differential.
DR   Gene3D; 2.130.10.130; -; 1.
DR   InterPro; IPR013519; Int_alpha_beta-p.
DR   InterPro; IPR028994; Integrin_alpha_N.
DR   SMART; SM00191; Int_alpha; 1.
DR   PROSITE; PS51470; FG_GAP; 1.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Proteomics identification {ECO:0000213|EPD:D6R9X8,
KW   ECO:0000213|MaxQB:D6R9X8, ECO:0000213|PeptideAtlas:D6R9X8};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Repeat {ECO:0000256|SAAS:SAAS00504086};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     32       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        33    142       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5003087501.
FT   REPEAT       38    103       FG-GAP. {ECO:0000256|PROSITE-
FT                                ProRule:PRU00803}.
SQ   SEQUENCE   142 AA;  15230 MW;  10B7329649AFE8B7 CRC64;
     MGPGPSRAPR APRLMLCALA LMVAAGGCVV SAFNLDTRFL VVKEAGNPGS LFGYSVALHR
     QTERQQRYLL LAGAPRELAV PDGYTNRTGA VYLCPLTAHK DDCERMNITV KNDPGHHIIE
     DMWLGVTVAS QGPAGRVLET AT
//