ID   D6R9S9_HUMAN            Unreviewed;       167 AA.
AC   D6R9S9;
DT   13-JUL-2010, integrated into UniProtKB/TrEMBL.
DT   13-JUL-2010, sequence version 1.
DT   16-JAN-2019, entry version 47.
DE   SubName: Full=N-acylethanolamine-hydrolyzing acid amidase {ECO:0000313|Ensembl:ENSP00000423142};
GN   Name=NAAA {ECO:0000313|Ensembl:ENSP00000423142};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000423142, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000423142, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15815621; DOI=10.1038/nature03466;
RA   Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H.,
RA   Minx P., Wagner-McPherson C., Layman D., Wylie K., Sekhon M.,
RA   Becker M.C., Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E.,
RA   Kremitzki C., Oddy L., Du H., Sun H., Bradshaw-Cordum H., Ali J.,
RA   Carter J., Cordes M., Harris A., Isak A., van Brunt A., Nguyen C.,
RA   Du F., Courtney L., Kalicki J., Ozersky P., Abbott S., Armstrong J.,
RA   Belter E.A., Caruso L., Cedroni M., Cotton M., Davidson T., Desai A.,
RA   Elliott G., Erb T., Fronick C., Gaige T., Haakenson W., Haglund K.,
RA   Holmes A., Harkins R., Kim K., Kruchowski S.S., Strong C.M.,
RA   Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K.,
RA   McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C.,
RA   Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N.,
RA   Swearengen-Shahid S., Snider J., Strong J.T., Thompson J., Yoakum M.,
RA   Leonard S., Pearman C., Trani L., Radionenko M., Waligorski J.E.,
RA   Wang C., Rock S.M., Tin-Wollam A.-M., Maupin R., Latreille P.,
RA   Wendl M.C., Yang S.-P., Pohl C., Wallis J.W., Spieth J., Bieri T.A.,
RA   Berkowicz N., Nelson J.O., Osborne J., Ding L., Meyer R., Sabo A.,
RA   Shotland Y., Sinha P., Wohldmann P.E., Cook L.L., Hickenbotham M.T.,
RA   Eldred J., Williams D., Jones T.A., She X., Ciccarelli F.D.,
RA   Izaurralde E., Taylor J., Schmutz J., Myers R.M., Cox D.R., Huang X.,
RA   McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C.,
RA   Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S.,
RA   Miller W., Eichler E.E., Bork P., Suyama M., Torrents D.,
RA   Waterston R.H., Wilson R.K.;
RT   "Generation and annotation of the DNA sequences of human chromosomes 2
RT   and 4.";
RL   Nature 434:724-731(2005).
RN   [2] {ECO:0000313|Ensembl:ENSP00000423142}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JUL-2011) to UniProtKB.
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DR   EMBL; AC110615; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; D6R9S9; -.
DR   jPOST; D6R9S9; -.
DR   MaxQB; D6R9S9; -.
DR   PeptideAtlas; D6R9S9; -.
DR   PRIDE; D6R9S9; -.
DR   Ensembl; ENST00000507187; ENSP00000423142; ENSG00000138744.
DR   UCSC; uc010iiz.2; human.
DR   EuPathDB; HostDB:ENSG00000138744.14; -.
DR   HGNC; HGNC:736; NAAA.
DR   OpenTargets; ENSG00000138744; -.
DR   eggNOG; ENOG410IJHJ; Eukaryota.
DR   eggNOG; ENOG4111HJY; LUCA.
DR   GeneTree; ENSGT00530000063548; -.
DR   ChiTaRS; NAAA; human.
DR   Proteomes; UP000005640; Chromosome 4.
DR   Bgee; ENSG00000138744; Expressed in 218 organ(s), highest expression level in leukocyte.
DR   ExpressionAtlas; D6R9S9; baseline and differential.
DR   InterPro; IPR029130; Acid_ceramidase_N.
DR   Pfam; PF15508; NAAA-beta; 1.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Proteomics identification {ECO:0000213|EPD:D6R9S9,
KW   ECO:0000213|MaxQB:D6R9S9, ECO:0000213|PeptideAtlas:D6R9S9};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     28       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        29    167       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5003087495.
FT   DOMAIN       32     91       NAAA-beta. {ECO:0000259|Pfam:PF15508}.
SQ   SEQUENCE   167 AA;  18523 MW;  2CF741F44A9FDD33 CRC64;
     MRTADREARP GLPSLLLLLL AGAGLSAASP PAAPRFNVSL DSVPELRWLP VLRHYDLDLV
     RAAMAQVIGD RVPKWVHVLI GKVVLELERF LPQPFTGEIR GMCDFMNLSL ADCLLVNLAY
     ESSVFCTSIV AQDSRGHIYH GRNLDYPFGN VLRKLTVDVQ FLKNGQV
//