ID   D3YTG3_HUMAN            Unreviewed;      1777 AA.
AC   D3YTG3;
DT   20-APR-2010, integrated into UniProtKB/TrEMBL.
DT   20-APR-2010, sequence version 1.
DT   16-JAN-2019, entry version 56.
DE   SubName: Full=Target of Nesh-SH3 {ECO:0000313|Ensembl:ENSP00000420524};
GN   Name=ABI3BP {ECO:0000313|Ensembl:ENSP00000420524};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000420524, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000420524, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16641997; DOI=10.1038/nature04728;
RA   Muzny D.M., Scherer S.E., Kaul R., Wang J., Yu J., Sudbrak R.,
RA   Buhay C.J., Chen R., Cree A., Ding Y., Dugan-Rocha S., Gill R.,
RA   Gunaratne P., Harris R.A., Hawes A.C., Hernandez J., Hodgson A.V.,
RA   Hume J., Jackson A., Khan Z.M., Kovar-Smith C., Lewis L.R.,
RA   Lozado R.J., Metzker M.L., Milosavljevic A., Miner G.R., Morgan M.B.,
RA   Nazareth L.V., Scott G., Sodergren E., Song X.Z., Steffen D., Wei S.,
RA   Wheeler D.A., Wright M.W., Worley K.C., Yuan Y., Zhang Z., Adams C.Q.,
RA   Ansari-Lari M.A., Ayele M., Brown M.J., Chen G., Chen Z.,
RA   Clendenning J., Clerc-Blankenburg K.P., Chen R., Chen Z., Davis C.,
RA   Delgado O., Dinh H.H., Dong W., Draper H., Ernst S., Fu G.,
RA   Gonzalez-Garay M.L., Garcia D.K., Gillett W., Gu J., Hao B.,
RA   Haugen E., Havlak P., He X., Hennig S., Hu S., Huang W., Jackson L.R.,
RA   Jacob L.S., Kelly S.H., Kube M., Levy R., Li Z., Liu B., Liu J.,
RA   Liu W., Lu J., Maheshwari M., Nguyen B.V., Okwuonu G.O., Palmeiri A.,
RA   Pasternak S., Perez L.M., Phelps K.A., Plopper F.J., Qiang B.,
RA   Raymond C., Rodriguez R., Saenphimmachak C., Santibanez J., Shen H.,
RA   Shen Y., Subramanian S., Tabor P.E., Verduzco D., Waldron L., Wang J.,
RA   Wang J., Wang Q., Williams G.A., Wong G.K., Yao Z., Zhang J.,
RA   Zhang X., Zhao G., Zhou J., Zhou Y., Nelson D., Lehrach H.,
RA   Reinhardt R., Naylor S.L., Yang H., Olson M., Weinstock G.,
RA   Gibbs R.A.;
RT   "The DNA sequence, annotation and analysis of human chromosome 3.";
RL   Nature 440:1194-1198(2006).
RN   [2] {ECO:0000313|Ensembl:ENSP00000420524}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JUL-2011) to UniProtKB.
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DR   EMBL; AC068763; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC069223; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC080014; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC093009; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC106721; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   RefSeq; XP_005247340.1; XM_005247283.2.
DR   UniGene; Hs.477015; -.
DR   ProteinModelPortal; D3YTG3; -.
DR   jPOST; D3YTG3; -.
DR   MaxQB; D3YTG3; -.
DR   PeptideAtlas; D3YTG3; -.
DR   PRIDE; D3YTG3; -.
DR   Ensembl; ENST00000471714; ENSP00000420524; ENSG00000154175.
DR   GeneID; 25890; -.
DR   UCSC; uc003duj.4; human.
DR   CTD; 25890; -.
DR   EuPathDB; HostDB:ENSG00000154175.16; -.
DR   HGNC; HGNC:17265; ABI3BP.
DR   OpenTargets; ENSG00000154175; -.
DR   GeneTree; ENSGT00530000063558; -.
DR   HOGENOM; HOG000065723; -.
DR   OMA; PHTTPQF; -.
DR   OrthoDB; 46073at2759; -.
DR   PhylomeDB; D3YTG3; -.
DR   ChiTaRS; ABI3BP; human.
DR   GenomeRNAi; 25890; -.
DR   Proteomes; UP000005640; Chromosome 3.
DR   Bgee; ENSG00000154175; Expressed in 197 organ(s), highest expression level in decidua.
DR   ExpressionAtlas; D3YTG3; baseline and differential.
DR   CDD; cd00063; FN3; 2.
DR   Gene3D; 2.60.40.10; -; 2.
DR   InterPro; IPR003961; FN3_dom.
DR   InterPro; IPR036116; FN3_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   Pfam; PF00041; fn3; 1.
DR   SUPFAM; SSF49265; SSF49265; 2.
DR   PROSITE; PS50853; FN3; 2.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Proteomics identification {ECO:0000213|MaxQB:D3YTG3,
KW   ECO:0000213|PeptideAtlas:D3YTG3};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     28       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        29   1777       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5003052914.
FT   DOMAIN      123    221       Fibronectin type-III.
FT                                {ECO:0000259|PROSITE:PS50853}.
FT   DOMAIN     1542   1635       Fibronectin type-III.
FT                                {ECO:0000259|PROSITE:PS50853}.
SQ   SEQUENCE   1777 AA;  195324 MW;  46405D5C1318EEAF CRC64;
     MRGGKCNMLS SLGCLLLCGS ITLALGNAQK LPKGKRPNLK VHINTTSDSI LLKFLRPSPN
     VKLEGLLLGY GSNVSPNQYF PLPAEGKFTE AIVDAEPKYL IVVRPAPPPS QKKSCSGKTR
     SRKPLQLVVG TLTPSSVFLS WGFLINPHHD WTLPSHCPND RFYTIRYREK DKEKKWIFQI
     CPATETIVEN LKPNTVYEFG VKDNVEGGIW SKIFNHKTVV GSKKVNGKIQ STYDQDHTVP
     AYVPRKLIPI TIIKQVIQNV THKDSAKSPE KAPLGGVILV HLIIPGLNET TVKLPASLMF
     EISDALKTQL AKNETLALPA ESKTPEVEKI SARPTTVTPE TVPRSTKPTT SSALDVSETT
     LVLSKRTPET LQTILIPQFE LPLSTLAPKS LPEFPEAKTP FPFEKPRGTL ASSEKPWIVP
     TAKISEDSKV LQPQTATYDV FSSPTTSDEP EISDSYTATS DRILDSIPPK TSRTLEQPRA
     TLAPSETPFV PQKLEIFTSP EMQPTTPAPQ QTTSIPSTPK RRPRPKPPRT KPERTTSAGT
     ITPKISKSPE PTWTTPAPGK TQFISLKPKI PLSPEVTHTK PAPEPQTLLP SQSTIGPETP
     GTKPSTTLAP RKTKRPGRRP RPRPRPKTTP SPEVPKSKPA LEPATIQPEP LVPTTASKPS
     ERPKTTHRPD APQIQPGSKP PKQLLPKPQT TAEPDMPPTK SVSEPVPFET EAPSMTIVPT
     TDIEPVTVRT EATVTTLAPK TSQRTRTRRP RPKHKTTPRP ETLQTKLDFG PITPGTSSAP
     TTTTKRTRRP HPKPKTTPHP EVPQTKLVPA TILEPVLRTE ASGTTAAPKV PQRTHRPHPK
     PKTTLSPEEL QTELVPATIF EPVSPIKEAP GTTFVPVTDL EPVTFRTEIP ATTLATKTSK
     RTRPPRPRPK TTPSPQAPET KPVPATVLEP VTLRPEASTT LASKTSQRTR RPRLRTKTTP
     RPEAPESKPV PTAELKPVTL RTETWVTTQA PKTSQRTRRP RPKTKTTPSP EVPQTKLVPS
     TDLEPGTLRT EAPKTMVVTT VLEPDTFRTK FPETTLAPKT QRTRRPRPRP KTTSSPEVPQ
     NKSVSVTGFE PVVHSTDAPG TTFALTELQT LILKPVTSPS LEMTESQPVS DVLESVTLST
     ESPKETIAPA KTDYVYPTAK APLWPEEPKT EVVESITYVS EPPETTLETS PLPSQSITLP
     SPDEPQTEPA PKQTPRAPPK PKTSPRPRIP QTQPVPKVPQ RVTAKPKTSP SPEVSYTTPA
     PKDVLLPHKP YPEVSQSEPA PLETRGIPFI PMISPSPSQE ELQTTLEETD QSTQEPFTTK
     IPRTTELAKT TQAPHRFYTT VRPRTSDKPH IRPVLNRTTT RPTRPKPSGM PSGNGVGTGV
     KQAPRPSGAD RNVSVDSTHP TKKPGTRRPP LPPRPTHPRR KPLPPNNVTG KPGSAGIISS
     GPITTPPLRS TPRPTGTPLE RIETDIKQPT VPASGEELEN ITDFSSSPTR ETDPLGKPRF
     KGPHVRYIQK PDNSPCSITD SVKRFPKEEA TEGNATSPPQ NPPTNLTVVT VEGCPSFVIL
     DWEKPLNDTV TEYEVISREN GSFSGKNKSI QMTNQTFSTV ENLKPNTSYE FQVKPKNPLG
     EGPVSNTVAF STESADPRVS EPVSAGRDAI WTERPFNSDS YSECKGKQYV KRTWYKKFVG
     VQLCNSLRYK IYLSDSLTGK FYNIGDQRGH GEDHCQFVDS FLDGRTGQQL TSDQLPIKEG
     YFRAVRQEPV QFGEIGGHTQ INYVQWYECG TTIPGKW
//