ID   C9JZZ0_HUMAN            Unreviewed;       162 AA.
AC   C9JZZ0;
DT   03-NOV-2009, integrated into UniProtKB/TrEMBL.
DT   03-NOV-2009, sequence version 1.
DT   12-SEP-2018, entry version 59.
DE   SubName: Full=Apolipoprotein A-V {ECO:0000313|Ensembl:ENSP00000399701};
DE   Flags: Fragment;
GN   Name=APOA5 {ECO:0000313|Ensembl:ENSP00000399701};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000399701, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000399701, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16554811; DOI=10.1038/nature04632;
RA   Taylor T.D., Noguchi H., Totoki Y., Toyoda A., Kuroki Y., Dewar K.,
RA   Lloyd C., Itoh T., Takeda T., Kim D.W., She X., Barlow K.F., Bloom T.,
RA   Bruford E., Chang J.L., Cuomo C.A., Eichler E., FitzGerald M.G.,
RA   Jaffe D.B., LaButti K., Nicol R., Park H.S., Seaman C., Sougnez C.,
RA   Yang X., Zimmer A.R., Zody M.C., Birren B.W., Nusbaum C., Fujiyama A.,
RA   Hattori M., Rogers J., Lander E.S., Sakaki Y.;
RT   "Human chromosome 11 DNA sequence and analysis including novel gene
RT   identification.";
RL   Nature 440:497-500(2006).
RN   [2] {ECO:0000313|Ensembl:ENSP00000399701}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JUL-2011) to UniProtKB.
RN   [3] {ECO:0000213|PubMed:24275569}
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX   PubMed=24275569; DOI=10.1016/j.jprot.2013.11.014;
RA   Bian Y., Song C., Cheng K., Dong M., Wang F., Huang J., Sun D.,
RA   Wang L., Ye M., Zou H.;
RT   "An enzyme assisted RP-RPLC approach for in-depth analysis of human
RT   liver phosphoproteome.";
RL   J. Proteomics 96:253-262(2014).
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|SAAS:SAAS00412673}.
CC   -!- SIMILARITY: Belongs to the apolipoprotein A1/A4/E family.
CC       {ECO:0000256|SAAS:SAAS00598075}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   -----------------------------------------------------------------------
DR   EMBL; AP006216; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; C9JZZ0; -.
DR   MaxQB; C9JZZ0; -.
DR   PeptideAtlas; C9JZZ0; -.
DR   PRIDE; C9JZZ0; -.
DR   Ensembl; ENST00000433069; ENSP00000399701; ENSG00000110243.
DR   UCSC; uc058hqt.1; human.
DR   EuPathDB; HostDB:ENSG00000110243.11; -.
DR   HGNC; HGNC:17288; APOA5.
DR   OpenTargets; ENSG00000110243; -.
DR   eggNOG; ENOG410IKFF; Eukaryota.
DR   eggNOG; ENOG410YHUG; LUCA.
DR   GeneTree; ENSGT00530000063081; -.
DR   Proteomes; UP000005640; Chromosome 11.
DR   Bgee; ENSG00000110243; Expressed in 31 organ(s), highest expression level in right lobe of liver.
DR   ExpressionAtlas; C9JZZ0; baseline and differential.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0008289; F:lipid binding; IEA:InterPro.
DR   GO; GO:0006869; P:lipid transport; IEA:UniProtKB-KW.
DR   GO; GO:0042157; P:lipoprotein metabolic process; IEA:InterPro.
DR   InterPro; IPR000074; ApoA_E.
DR   Pfam; PF01442; Apolipoprotein; 1.
PE   1: Evidence at protein level;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Lipid transport {ECO:0000256|SAAS:SAAS00491985};
KW   Proteomics identification {ECO:0000213|MaxQB:C9JZZ0,
KW   ECO:0000213|PeptideAtlas:C9JZZ0};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Secreted {ECO:0000256|SAAS:SAAS00491987};
KW   Signal {ECO:0000256|SAM:SignalP};
KW   Transport {ECO:0000256|SAAS:SAAS00491985}.
FT   SIGNAL        1     23       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        24    162       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5002997484.
FT   COILED       93    113       {ECO:0000256|SAM:Coils}.
FT   COILED      137    157       {ECO:0000256|SAM:Coils}.
FT   NON_TER     162    162       {ECO:0000313|Ensembl:ENSP00000399701}.
SQ   SEQUENCE   162 AA;  18541 MW;  AAE32CBA643E470C CRC64;
     MASMAAVLTW ALALLSAFSA TQARKGFWDY FSQTSGDKGR VEQIHQQKMA REPATLKDSL
     EQDLNNMNKF LEKLRPLSGS EAPRLPQDPV GMRRQLQEEL EEVKARLQPY MAEAHELVGW
     NLEGLRQQLK PYTMDLMEQV ALRVQELQEQ LRVVGEDTKA QL
//