ID   C9JYX9_HUMAN            Unreviewed;       303 AA.
AC   C9JYX9;
DT   03-NOV-2009, integrated into UniProtKB/TrEMBL.
DT   03-NOV-2009, sequence version 1.
DT   05-DEC-2018, entry version 61.
DE   SubName: Full=Procollagen C-endopeptidase enhancer 2 {ECO:0000313|Ensembl:ENSP00000419842};
GN   Name=PCOLCE2 {ECO:0000313|Ensembl:ENSP00000419842};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000419842, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000419842, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16641997; DOI=10.1038/nature04728;
RA   Muzny D.M., Scherer S.E., Kaul R., Wang J., Yu J., Sudbrak R.,
RA   Buhay C.J., Chen R., Cree A., Ding Y., Dugan-Rocha S., Gill R.,
RA   Gunaratne P., Harris R.A., Hawes A.C., Hernandez J., Hodgson A.V.,
RA   Hume J., Jackson A., Khan Z.M., Kovar-Smith C., Lewis L.R.,
RA   Lozado R.J., Metzker M.L., Milosavljevic A., Miner G.R., Morgan M.B.,
RA   Nazareth L.V., Scott G., Sodergren E., Song X.Z., Steffen D., Wei S.,
RA   Wheeler D.A., Wright M.W., Worley K.C., Yuan Y., Zhang Z., Adams C.Q.,
RA   Ansari-Lari M.A., Ayele M., Brown M.J., Chen G., Chen Z.,
RA   Clendenning J., Clerc-Blankenburg K.P., Chen R., Chen Z., Davis C.,
RA   Delgado O., Dinh H.H., Dong W., Draper H., Ernst S., Fu G.,
RA   Gonzalez-Garay M.L., Garcia D.K., Gillett W., Gu J., Hao B.,
RA   Haugen E., Havlak P., He X., Hennig S., Hu S., Huang W., Jackson L.R.,
RA   Jacob L.S., Kelly S.H., Kube M., Levy R., Li Z., Liu B., Liu J.,
RA   Liu W., Lu J., Maheshwari M., Nguyen B.V., Okwuonu G.O., Palmeiri A.,
RA   Pasternak S., Perez L.M., Phelps K.A., Plopper F.J., Qiang B.,
RA   Raymond C., Rodriguez R., Saenphimmachak C., Santibanez J., Shen H.,
RA   Shen Y., Subramanian S., Tabor P.E., Verduzco D., Waldron L., Wang J.,
RA   Wang J., Wang Q., Williams G.A., Wong G.K., Yao Z., Zhang J.,
RA   Zhang X., Zhao G., Zhou J., Zhou Y., Nelson D., Lehrach H.,
RA   Reinhardt R., Naylor S.L., Yang H., Olson M., Weinstock G.,
RA   Gibbs R.A.;
RT   "The DNA sequence, annotation and analysis of human chromosome 3.";
RL   Nature 440:1194-1198(2006).
RN   [2] {ECO:0000313|Ensembl:ENSP00000419842}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JUL-2011) to UniProtKB.
CC   -!- CAUTION: Lacks conserved residue(s) required for the propagation
CC       of feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00059}.
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DR   EMBL; AC021074; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC022291; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; C9JYX9; -.
DR   MaxQB; C9JYX9; -.
DR   PeptideAtlas; C9JYX9; -.
DR   PRIDE; C9JYX9; -.
DR   Ensembl; ENST00000485766; ENSP00000419842; ENSG00000163710.
DR   UCSC; uc062opr.1; human.
DR   EuPathDB; HostDB:ENSG00000163710.7; -.
DR   HGNC; HGNC:8739; PCOLCE2.
DR   OpenTargets; ENSG00000163710; -.
DR   eggNOG; ENOG410IEMJ; Eukaryota.
DR   eggNOG; ENOG410Y9AW; LUCA.
DR   GeneTree; ENSGT00940000157649; -.
DR   HOGENOM; HOG000198427; -.
DR   ChiTaRS; PCOLCE2; human.
DR   Proteomes; UP000005640; Chromosome 3.
DR   Bgee; ENSG00000163710; Expressed in 191 organ(s), highest expression level in tendon of biceps brachii.
DR   ExpressionAtlas; C9JYX9; baseline and differential.
DR   CDD; cd00041; CUB; 2.
DR   Gene3D; 2.60.120.290; -; 2.
DR   InterPro; IPR000859; CUB_dom.
DR   InterPro; IPR035914; Sperma_CUB_dom_sf.
DR   Pfam; PF00431; CUB; 2.
DR   SMART; SM00042; CUB; 2.
DR   SUPFAM; SSF49854; SSF49854; 2.
DR   PROSITE; PS01180; CUB; 2.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Disulfide bond {ECO:0000256|PROSITE-ProRule:PRU00059,
KW   ECO:0000256|SAAS:SAAS01008102};
KW   Proteomics identification {ECO:0000213|MaxQB:C9JYX9,
KW   ECO:0000213|PeptideAtlas:C9JYX9};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     23       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        24    303       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5002997927.
FT   DOMAIN       33    144       CUB. {ECO:0000259|PROSITE:PS01180}.
FT   DOMAIN      154    236       CUB. {ECO:0000259|PROSITE:PS01180}.
FT   DISULFID    154    181       {ECO:0000256|PROSITE-ProRule:PRU00059}.
SQ   SEQUENCE   303 AA;  33807 MW;  E11DC56B2638924E CRC64;
     MRGANAWAPL CLLLAAATQL SRQQSPERPV FTCGGILTGE SGFIGSEGFP GVYPPNSKCT
     WKITVPEGKV VVLNFRFIDL ESDNLCRYDF VDVYNGHANG QRIGRFCGTF RPGALVSSGN
     KMMVQMISDA NTAGNGFMAM FSAAEPNERG DQYCGGLLDR PSGSFKTPNW PDRDYPAGVT
     CVWHIVAPKN QLIELKFEKF DVERDNYCRY DYVAVFNGGE VNDARRIGKY CGDSPPAISR
     HCYHNHHSRW EFARHSLDHQ HLQRGKFGDS AGGQEHECQA DCRLQAVPSP QKRSKLHYYG
     PSR
//