ID   C9JYX1_HUMAN            Unreviewed;       189 AA.
AC   C9JYX1;
DT   03-NOV-2009, integrated into UniProtKB/TrEMBL.
DT   05-OCT-2016, sequence version 8.
DT   16-JAN-2019, entry version 66.
DE   SubName: Full=Transmembrane protein 209 {ECO:0000313|Ensembl:ENSP00000419852};
DE   Flags: Fragment;
GN   Name=TMEM209 {ECO:0000313|Ensembl:ENSP00000419852};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000419852, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000419852, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=12853948; DOI=10.1038/nature01782;
RA   Hillier L.W., Fulton R.S., Fulton L.A., Graves T.A., Pepin K.H.,
RA   Wagner-McPherson C., Layman D., Maas J., Jaeger S., Walker R.,
RA   Wylie K., Sekhon M., Becker M.C., O'Laughlin M.D., Schaller M.E.,
RA   Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E., Cordes M., Du H.,
RA   Sun H., Edwards J., Bradshaw-Cordum H., Ali J., Andrews S., Isak A.,
RA   Vanbrunt A., Nguyen C., Du F., Lamar B., Courtney L., Kalicki J.,
RA   Ozersky P., Bielicki L., Scott K., Holmes A., Harkins R., Harris A.,
RA   Strong C.M., Hou S., Tomlinson C., Dauphin-Kohlberg S.,
RA   Kozlowicz-Reilly A., Leonard S., Rohlfing T., Rock S.M.,
RA   Tin-Wollam A.-M., Abbott A., Minx P., Maupin R., Strowmatt C.,
RA   Latreille P., Miller N., Johnson D., Murray J., Woessner J.P.,
RA   Wendl M.C., Yang S.-P., Schultz B.R., Wallis J.W., Spieth J.,
RA   Bieri T.A., Nelson J.O., Berkowicz N., Wohldmann P.E., Cook L.L.,
RA   Hickenbotham M.T., Eldred J., Williams D., Bedell J.A., Mardis E.R.,
RA   Clifton S.W., Chissoe S.L., Marra M.A., Raymond C., Haugen E.,
RA   Gillett W., Zhou Y., James R., Phelps K., Iadanoto S., Bubb K.,
RA   Simms E., Levy R., Clendenning J., Kaul R., Kent W.J., Furey T.S.,
RA   Baertsch R.A., Brent M.R., Keibler E., Flicek P., Bork P., Suyama M.,
RA   Bailey J.A., Portnoy M.E., Torrents D., Chinwalla A.T., Gish W.R.,
RA   Eddy S.R., McPherson J.D., Olson M.V., Eichler E.E., Green E.D.,
RA   Waterston R.H., Wilson R.K.;
RT   "The DNA sequence of human chromosome 7.";
RL   Nature 424:157-164(2003).
RN   [2] {ECO:0000213|PubMed:20068231}
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX   PubMed=20068231; DOI=10.1126/scisignal.2000475;
RA   Olsen J.V., Vermeulen M., Santamaria A., Kumar C., Miller M.L.,
RA   Jensen L.J., Gnad F., Cox J., Jensen T.S., Nigg E.A., Brunak S.,
RA   Mann M.;
RT   "Quantitative phosphoproteomics reveals widespread full
RT   phosphorylation site occupancy during mitosis.";
RL   Sci. Signal. 3:ra3-RA3(2010).
RN   [3] {ECO:0000313|Ensembl:ENSP00000419852}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JUL-2011) to UniProtKB.
RN   [4] {ECO:0000213|PubMed:23186163}
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX   PubMed=23186163;
RA   Zhou H., Di Palma S., Preisinger C., Peng M., Polat A.N., Heck A.J.,
RA   Mohammed S.;
RT   "Toward a comprehensive characterization of a human cancer cell
RT   phosphoproteome.";
RL   J. Proteome Res. 12:260-271(2013).
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DR   EMBL; AC087071; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; C9JYX1; -.
DR   jPOST; C9JYX1; -.
DR   PeptideAtlas; C9JYX1; -.
DR   PRIDE; C9JYX1; -.
DR   Ensembl; ENST00000471985; ENSP00000419852; ENSG00000146842.
DR   UCSC; uc064hyr.1; human.
DR   EuPathDB; HostDB:ENSG00000146842.16; -.
DR   HGNC; HGNC:21898; TMEM209.
DR   OpenTargets; ENSG00000146842; -.
DR   eggNOG; KOG4670; Eukaryota.
DR   eggNOG; ENOG410XQWI; LUCA.
DR   GeneTree; ENSGT00390000013963; -.
DR   ChiTaRS; TMEM209; human.
DR   Proteomes; UP000005640; Chromosome 7.
DR   Bgee; ENSG00000146842; Expressed in 200 organ(s), highest expression level in metanephros.
DR   ExpressionAtlas; C9JYX1; baseline and differential.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR019176; Cytochrome_B561-rel.
DR   PANTHER; PTHR21780; PTHR21780; 1.
DR   Pfam; PF09786; CytochromB561_N; 1.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Proteomics identification {ECO:0000213|EPD:C9JYX1,
KW   ECO:0000213|MaxQB:C9JYX1, ECO:0000213|PeptideAtlas:C9JYX1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   SIGNAL        1     15       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        16    189       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5012971739.
FT   TRANSMEM     71     87       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    107    126       Helical. {ECO:0000256|SAM:Phobius}.
FT   NON_TER     189    189       {ECO:0000313|Ensembl:ENSP00000419852}.
SQ   SEQUENCE   189 AA;  20676 MW;  937BE7E1747A4183 CRC64;
     MLLGLLSLWK GLTLSPRLEC SGTILAHRNL GFPGSSDSPA SASRMQGEAH PSASLIDRTI
     KMRKETEARK VVLAWGLLNV SMAGMIYTEM TGKLISSYYN VTYWPLWYIE LALASLFSLN
     ALFDFWRYFK YTVAPTSLVV SPGQQTLLGL KTAVVQTTPP HDLAATQIPP APPSPSIQGQ
     SVLSYSPSR
//