ID   C9JYP5_HUMAN            Unreviewed;       180 AA.
AC   C9JYP5;
DT   03-NOV-2009, integrated into UniProtKB/TrEMBL.
DT   03-NOV-2009, sequence version 1.
DT   05-DEC-2018, entry version 59.
DE   SubName: Full=Lysosome-associated membrane glycoprotein 3 {ECO:0000313|Ensembl:ENSP00000419059};
DE   Flags: Fragment;
GN   Name=LAMP3 {ECO:0000313|Ensembl:ENSP00000419059};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000419059, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000419059, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16641997; DOI=10.1038/nature04728;
RA   Muzny D.M., Scherer S.E., Kaul R., Wang J., Yu J., Sudbrak R.,
RA   Buhay C.J., Chen R., Cree A., Ding Y., Dugan-Rocha S., Gill R.,
RA   Gunaratne P., Harris R.A., Hawes A.C., Hernandez J., Hodgson A.V.,
RA   Hume J., Jackson A., Khan Z.M., Kovar-Smith C., Lewis L.R.,
RA   Lozado R.J., Metzker M.L., Milosavljevic A., Miner G.R., Morgan M.B.,
RA   Nazareth L.V., Scott G., Sodergren E., Song X.Z., Steffen D., Wei S.,
RA   Wheeler D.A., Wright M.W., Worley K.C., Yuan Y., Zhang Z., Adams C.Q.,
RA   Ansari-Lari M.A., Ayele M., Brown M.J., Chen G., Chen Z.,
RA   Clendenning J., Clerc-Blankenburg K.P., Chen R., Chen Z., Davis C.,
RA   Delgado O., Dinh H.H., Dong W., Draper H., Ernst S., Fu G.,
RA   Gonzalez-Garay M.L., Garcia D.K., Gillett W., Gu J., Hao B.,
RA   Haugen E., Havlak P., He X., Hennig S., Hu S., Huang W., Jackson L.R.,
RA   Jacob L.S., Kelly S.H., Kube M., Levy R., Li Z., Liu B., Liu J.,
RA   Liu W., Lu J., Maheshwari M., Nguyen B.V., Okwuonu G.O., Palmeiri A.,
RA   Pasternak S., Perez L.M., Phelps K.A., Plopper F.J., Qiang B.,
RA   Raymond C., Rodriguez R., Saenphimmachak C., Santibanez J., Shen H.,
RA   Shen Y., Subramanian S., Tabor P.E., Verduzco D., Waldron L., Wang J.,
RA   Wang J., Wang Q., Williams G.A., Wong G.K., Yao Z., Zhang J.,
RA   Zhang X., Zhao G., Zhou J., Zhou Y., Nelson D., Lehrach H.,
RA   Reinhardt R., Naylor S.L., Yang H., Olson M., Weinstock G.,
RA   Gibbs R.A.;
RT   "The DNA sequence, annotation and analysis of human chromosome 3.";
RL   Nature 440:1194-1198(2006).
RN   [2] {ECO:0000313|Ensembl:ENSP00000419059}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JUL-2011) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Lysosome membrane {ECO:0000256|PROSITE-
CC       ProRule:PRU00740}; Single-pass type I membrane protein
CC       {ECO:0000256|PROSITE-ProRule:PRU00740}.
CC   -!- SIMILARITY: Belongs to the LAMP family. {ECO:0000256|PROSITE-
CC       ProRule:PRU00740}.
CC   -!- CAUTION: Lacks conserved residue(s) required for the propagation
CC       of feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00740}.
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DR   EMBL; AC104641; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; C9JYP5; -.
DR   PeptideAtlas; C9JYP5; -.
DR   PRIDE; C9JYP5; -.
DR   Ensembl; ENST00000476015; ENSP00000419059; ENSG00000078081.
DR   UCSC; uc062qnr.1; human.
DR   EuPathDB; HostDB:ENSG00000078081.7; -.
DR   HGNC; HGNC:14582; LAMP3.
DR   OpenTargets; ENSG00000078081; -.
DR   eggNOG; KOG4818; Eukaryota.
DR   eggNOG; ENOG410XQ96; LUCA.
DR   GeneTree; ENSGT00940000164015; -.
DR   HOGENOM; HOG000004835; -.
DR   Proteomes; UP000005640; Chromosome 3.
DR   Bgee; ENSG00000078081; Expressed in 132 organ(s), highest expression level in visceral pleura.
DR   ExpressionAtlas; C9JYP5; baseline and differential.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-UniRule.
DR   GO; GO:0005765; C:lysosomal membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR002000; Lysosome-assoc_membr_glycop.
DR   PANTHER; PTHR11506; PTHR11506; 1.
DR   PROSITE; PS51407; LAMP_3; 1.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Lysosome {ECO:0000256|PROSITE-ProRule:PRU00740};
KW   Membrane {ECO:0000256|PROSITE-ProRule:PRU00740};
KW   Proteomics identification {ECO:0000213|MaxQB:C9JYP5,
KW   ECO:0000213|PeptideAtlas:C9JYP5};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|PROSITE-ProRule:PRU00740}.
FT   SIGNAL        1     20       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        21    180       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5002996610.
FT   NON_TER     180    180       {ECO:0000313|Ensembl:ENSP00000419059}.
SQ   SEQUENCE   180 AA;  18779 MW;  5D6F55344C3E503F CRC64;
     MPRQLSAAAA LFASLAVILH DGSQMRAKAF PETRDYSQPT AAATVQDIKK PVQQPAKQAP
     HQTLAARFMD GHITFQTAAT VKIPTTTPAT TKNTATTSPI TYTLVTTQAT PNNSHTAPPV
     TEVTVGPSLA PYSLPPTITP PAHTTGTSSS TVSHTTGNTT QPSNQTTLPA TLSIALHKST
//