ID   C9JY47_HUMAN            Unreviewed;       543 AA.
AC   C9JY47;
DT   03-NOV-2009, integrated into UniProtKB/TrEMBL.
DT   16-NOV-2011, sequence version 2.
DT   16-JAN-2019, entry version 51.
DE   SubName: Full=HERV-H LTR-associating protein 1 {ECO:0000313|Ensembl:ENSP00000407107};
GN   Name=HHLA1 {ECO:0000313|Ensembl:ENSP00000407107};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000407107, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000407107, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16421571; DOI=10.1038/nature04406;
RA   Nusbaum C., Mikkelsen T.S., Zody M.C., Asakawa S., Taudien S.,
RA   Garber M., Kodira C.D., Schueler M.G., Shimizu A., Whittaker C.A.,
RA   Chang J.L., Cuomo C.A., Dewar K., FitzGerald M.G., Yang X.,
RA   Allen N.R., Anderson S., Asakawa T., Blechschmidt K., Bloom T.,
RA   Borowsky M.L., Butler J., Cook A., Corum B., DeArellano K.,
RA   DeCaprio D., Dooley K.T., Dorris L. III, Engels R., Glockner G.,
RA   Hafez N., Hagopian D.S., Hall J.L., Ishikawa S.K., Jaffe D.B.,
RA   Kamat A., Kudoh J., Lehmann R., Lokitsang T., Macdonald P.,
RA   Major J.E., Matthews C.D., Mauceli E., Menzel U., Mihalev A.H.,
RA   Minoshima S., Murayama Y., Naylor J.W., Nicol R., Nguyen C.,
RA   O'Leary S.B., O'Neill K., Parker S.C., Polley A., Raymond C.K.,
RA   Reichwald K., Rodriguez J., Sasaki T., Schilhabel M., Siddiqui R.,
RA   Smith C.L., Sneddon T.P., Talamas J.A., Tenzin P., Topham K.,
RA   Venkataraman V., Wen G., Yamazaki S., Young S.K., Zeng Q.,
RA   Zimmer A.R., Rosenthal A., Birren B.W., Platzer M., Shimizu N.,
RA   Lander E.S.;
RT   "DNA sequence and analysis of human chromosome 8.";
RL   Nature 439:331-335(2006).
RN   [2] {ECO:0000313|Ensembl:ENSP00000407107}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JUL-2011) to UniProtKB.
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DR   EMBL; AC100868; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC131042; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; C9JY47; -.
DR   STRING; 9606.ENSP00000407107; -.
DR   PaxDb; C9JY47; -.
DR   PRIDE; C9JY47; -.
DR   Ensembl; ENST00000434736; ENSP00000407107; ENSG00000132297.
DR   UCSC; uc064qho.1; human.
DR   EuPathDB; HostDB:ENSG00000132297.11; -.
DR   HGNC; HGNC:4904; HHLA1.
DR   OpenTargets; ENSG00000132297; -.
DR   eggNOG; ENOG410IKIT; Eukaryota.
DR   eggNOG; ENOG410YXPX; LUCA.
DR   GeneTree; ENSGT00530000064699; -.
DR   HOGENOM; HOG000132989; -.
DR   OMA; DFWEMAE; -.
DR   TreeFam; TF341554; -.
DR   Proteomes; UP000005640; Chromosome 8.
DR   Bgee; ENSG00000132297; Expressed in 8 organ(s), highest expression level in secondary oocyte.
DR   ExpressionAtlas; C9JY47; baseline and differential.
DR   InterPro; IPR037643; HHLA1.
DR   PANTHER; PTHR15299; PTHR15299; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     29       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        30    543       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5002996608.
SQ   SEQUENCE   543 AA;  59405 MW;  D2C5C87ECB06B3C0 CRC64;
     MLGFLSRGPS MKLCMGLACV LSLWNTVSGI KGEAKKEKGM TFLPTTGKWV IRAPFQLTCL
     EIKMLRRKKM GHSRAALNPD LLLSGLREEE RKEKGVAFLA TTELPARSID LSALNLTELV
     NGMLSRALKD SKKFFSLLSV TSYSSFAFHK FSVAVYNISN LKTVDPAKFP TRYCYCLNNR
     TNDLSDFTAL LVDIIGNSTS YLTEIFKSTS ILSVNQSNES DCIFICVMTG KSGRNLSDFW
     EIEEKYPIIN YTFTSGLSGV LGAATRGTAR TSKPTTKSQK TLPSTSPGHW TQSTPWASAL
     RSSPWTETAA PSETEETLNT GRPPELPARA TATWFSASHT LPALATRRVA RTQWLTADRQ
     TWASISSVPW AQTISEKKPG GSLWETRSSP PTTAGTEEAM NTTSLLAPAA EIMATPGSPS
     QASPTLGAFT HGTQTPSPTK ATAPRYPQTG DLSAEWPFTA GEEPVLVPRP HQVSRCPQPL
     FKVGAMAAAP LTLAIQRLNP CLMELCQFFQ QCLCMSQRSP RTEDMSSFIN PYQSSTSKIS
     WKT
//