ID   C9JY13_HUMAN            Unreviewed;       144 AA.
AC   C9JY13;
DT   03-NOV-2009, integrated into UniProtKB/TrEMBL.
DT   05-OCT-2016, sequence version 10.
DT   05-DEC-2018, entry version 64.
DE   SubName: Full=HERV-H LTR-associating protein 2 {ECO:0000313|Ensembl:ENSP00000419940};
DE   Flags: Fragment;
GN   Name=HHLA2 {ECO:0000313|Ensembl:ENSP00000419940};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000419940, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000419940, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16641997; DOI=10.1038/nature04728;
RA   Muzny D.M., Scherer S.E., Kaul R., Wang J., Yu J., Sudbrak R.,
RA   Buhay C.J., Chen R., Cree A., Ding Y., Dugan-Rocha S., Gill R.,
RA   Gunaratne P., Harris R.A., Hawes A.C., Hernandez J., Hodgson A.V.,
RA   Hume J., Jackson A., Khan Z.M., Kovar-Smith C., Lewis L.R.,
RA   Lozado R.J., Metzker M.L., Milosavljevic A., Miner G.R., Morgan M.B.,
RA   Nazareth L.V., Scott G., Sodergren E., Song X.Z., Steffen D., Wei S.,
RA   Wheeler D.A., Wright M.W., Worley K.C., Yuan Y., Zhang Z., Adams C.Q.,
RA   Ansari-Lari M.A., Ayele M., Brown M.J., Chen G., Chen Z.,
RA   Clendenning J., Clerc-Blankenburg K.P., Chen R., Chen Z., Davis C.,
RA   Delgado O., Dinh H.H., Dong W., Draper H., Ernst S., Fu G.,
RA   Gonzalez-Garay M.L., Garcia D.K., Gillett W., Gu J., Hao B.,
RA   Haugen E., Havlak P., He X., Hennig S., Hu S., Huang W., Jackson L.R.,
RA   Jacob L.S., Kelly S.H., Kube M., Levy R., Li Z., Liu B., Liu J.,
RA   Liu W., Lu J., Maheshwari M., Nguyen B.V., Okwuonu G.O., Palmeiri A.,
RA   Pasternak S., Perez L.M., Phelps K.A., Plopper F.J., Qiang B.,
RA   Raymond C., Rodriguez R., Saenphimmachak C., Santibanez J., Shen H.,
RA   Shen Y., Subramanian S., Tabor P.E., Verduzco D., Waldron L., Wang J.,
RA   Wang J., Wang Q., Williams G.A., Wong G.K., Yao Z., Zhang J.,
RA   Zhang X., Zhao G., Zhou J., Zhou Y., Nelson D., Lehrach H.,
RA   Reinhardt R., Naylor S.L., Yang H., Olson M., Weinstock G.,
RA   Gibbs R.A.;
RT   "The DNA sequence, annotation and analysis of human chromosome 3.";
RL   Nature 440:1194-1198(2006).
RN   [2] {ECO:0000313|Ensembl:ENSP00000419940}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JUL-2011) to UniProtKB.
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DR   EMBL; AC078855; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC135308; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; C9JY13; -.
DR   PeptideAtlas; C9JY13; -.
DR   PRIDE; C9JY13; -.
DR   Ensembl; ENST00000463019; ENSP00000419940; ENSG00000114455.
DR   UCSC; uc062mgg.1; human.
DR   EuPathDB; HostDB:ENSG00000114455.13; -.
DR   HGNC; HGNC:4905; HHLA2.
DR   OpenTargets; ENSG00000114455; -.
DR   eggNOG; ENOG410IW89; Eukaryota.
DR   eggNOG; ENOG410YQH2; LUCA.
DR   GeneTree; ENSGT00940000162944; -.
DR   HOGENOM; HOG000205081; -.
DR   ChiTaRS; HHLA2; human.
DR   Proteomes; UP000005640; Chromosome 3.
DR   Bgee; ENSG00000114455; Expressed in 73 organ(s), highest expression level in mucosa of transverse colon.
DR   ExpressionAtlas; C9JY13; baseline and differential.
DR   Gene3D; 2.60.40.10; -; 1.
DR   InterPro; IPR036179; Ig-like_dom_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR013106; Ig_V-set.
DR   Pfam; PF07686; V-set; 1.
DR   SUPFAM; SSF48726; SSF48726; 1.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Proteomics identification {ECO:0000213|PeptideAtlas:C9JY13};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     22       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        23    144       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5008412932.
FT   DOMAIN       46    138       IGv. {ECO:0000259|Pfam:PF07686}.
FT   NON_TER     144    144       {ECO:0000313|Ensembl:ENSP00000419940}.
SQ   SEQUENCE   144 AA;  16401 MW;  B19B67064A2EE89C CRC64;
     MKAQTALSFF LILITSLSGS QGIFPLAFFI YVPMNEQIVI GRLDEDIILP SSFERGSEVV
     IHWKYQDSYK VHSYYKGSDH LESQDPRYAN RTSLFYNEIQ NGNASLFFRR VSLLDEGIYT
     CYVGTAIQVI TNKVVLKVGV FLTP
//