ID   C9JUX7_HUMAN            Unreviewed;       203 AA.
AC   C9JUX7;
DT   03-NOV-2009, integrated into UniProtKB/TrEMBL.
DT   03-NOV-2009, sequence version 1.
DT   16-JAN-2019, entry version 58.
DE   SubName: Full=Carboxypeptidase B {ECO:0000313|Ensembl:ENSP00000419427};
DE   Flags: Fragment;
GN   Name=CPB1 {ECO:0000313|Ensembl:ENSP00000419427};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000419427, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000419427, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16641997; DOI=10.1038/nature04728;
RA   Muzny D.M., Scherer S.E., Kaul R., Wang J., Yu J., Sudbrak R.,
RA   Buhay C.J., Chen R., Cree A., Ding Y., Dugan-Rocha S., Gill R.,
RA   Gunaratne P., Harris R.A., Hawes A.C., Hernandez J., Hodgson A.V.,
RA   Hume J., Jackson A., Khan Z.M., Kovar-Smith C., Lewis L.R.,
RA   Lozado R.J., Metzker M.L., Milosavljevic A., Miner G.R., Morgan M.B.,
RA   Nazareth L.V., Scott G., Sodergren E., Song X.Z., Steffen D., Wei S.,
RA   Wheeler D.A., Wright M.W., Worley K.C., Yuan Y., Zhang Z., Adams C.Q.,
RA   Ansari-Lari M.A., Ayele M., Brown M.J., Chen G., Chen Z.,
RA   Clendenning J., Clerc-Blankenburg K.P., Chen R., Chen Z., Davis C.,
RA   Delgado O., Dinh H.H., Dong W., Draper H., Ernst S., Fu G.,
RA   Gonzalez-Garay M.L., Garcia D.K., Gillett W., Gu J., Hao B.,
RA   Haugen E., Havlak P., He X., Hennig S., Hu S., Huang W., Jackson L.R.,
RA   Jacob L.S., Kelly S.H., Kube M., Levy R., Li Z., Liu B., Liu J.,
RA   Liu W., Lu J., Maheshwari M., Nguyen B.V., Okwuonu G.O., Palmeiri A.,
RA   Pasternak S., Perez L.M., Phelps K.A., Plopper F.J., Qiang B.,
RA   Raymond C., Rodriguez R., Saenphimmachak C., Santibanez J., Shen H.,
RA   Shen Y., Subramanian S., Tabor P.E., Verduzco D., Waldron L., Wang J.,
RA   Wang J., Wang Q., Williams G.A., Wong G.K., Yao Z., Zhang J.,
RA   Zhang X., Zhao G., Zhou J., Zhou Y., Nelson D., Lehrach H.,
RA   Reinhardt R., Naylor S.L., Yang H., Olson M., Weinstock G.,
RA   Gibbs R.A.;
RT   "The DNA sequence, annotation and analysis of human chromosome 3.";
RL   Nature 440:1194-1198(2006).
RN   [2] {ECO:0000313|Ensembl:ENSP00000419427}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JUL-2011) to UniProtKB.
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DR   EMBL; AC024897; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC092979; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; C9JUX7; -.
DR   SMR; C9JUX7; -.
DR   jPOST; C9JUX7; -.
DR   PeptideAtlas; C9JUX7; -.
DR   PRIDE; C9JUX7; -.
DR   Ensembl; ENST00000468341; ENSP00000419427; ENSG00000153002.
DR   UCSC; uc062ovd.1; human.
DR   EuPathDB; HostDB:ENSG00000153002.11; -.
DR   HGNC; HGNC:2299; CPB1.
DR   OpenTargets; ENSG00000153002; -.
DR   GeneTree; ENSGT00940000157819; -.
DR   HOGENOM; HOG000252967; -.
DR   ChiTaRS; CPB1; human.
DR   Proteomes; UP000005640; Chromosome 3.
DR   Bgee; ENSG00000153002; Expressed in 104 organ(s), highest expression level in body of pancreas.
DR   ExpressionAtlas; C9JUX7; baseline and differential.
DR   GO; GO:0004181; F:metallocarboxypeptidase activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   Gene3D; 3.30.70.340; -; 1.
DR   InterPro; IPR036990; M14A-like_propep.
DR   InterPro; IPR003146; M14A_act_pep.
DR   InterPro; IPR000834; Peptidase_M14.
DR   Pfam; PF00246; Peptidase_M14; 1.
DR   Pfam; PF02244; Propep_M14; 1.
DR   PROSITE; PS00132; CARBOXYPEPT_ZN_1; 1.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Proteomics identification {ECO:0000213|MaxQB:C9JUX7,
KW   ECO:0000213|PeptideAtlas:C9JUX7};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     15       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        16    203       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5012745473.
FT   DOMAIN      133    155       Peptidase_M14.
FT                                {ECO:0000259|PROSITE:PS00132}.
FT   NON_TER     203    203       {ECO:0000313|Ensembl:ENSP00000419427}.
SQ   SEQUENCE   203 AA;  23650 MW;  7A4AF9E004FFB03B CRC64;
     MLALLVLVTV ALASAHHGGE HFEGEKVFRV NVEDENHINI IRELASTTQI DFWKPDSVTQ
     IKPHSTVDFR VKAEDTVTVE NVLKQNELQY KVLISNLRNV VEAQFDSRVR ATGHSYEKYN
     KWETVGKAGQ NKPAIFMDCG FHAREWISPA FCQWFVREAV RTYGREIQVT ELLDKLDFYV
     LPVLNIDGYI YTWTKSRFWR KTR
//