ID   C9JUE4_HUMAN            Unreviewed;        85 AA.
AC   C9JUE4;
DT   03-NOV-2009, integrated into UniProtKB/TrEMBL.
DT   03-NOV-2009, sequence version 1.
DT   05-DEC-2018, entry version 51.
DE   RecName: Full=Carbohydrate sulfotransferase {ECO:0000256|RuleBase:RU364020};
DE            EC=2.8.2.- {ECO:0000256|RuleBase:RU364020};
DE   Flags: Fragment;
GN   Name=CHST10 {ECO:0000313|Ensembl:ENSP00000407525};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000407525, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000407525, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15815621; DOI=10.1038/nature03466;
RA   Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H.,
RA   Minx P., Wagner-McPherson C., Layman D., Wylie K., Sekhon M.,
RA   Becker M.C., Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E.,
RA   Kremitzki C., Oddy L., Du H., Sun H., Bradshaw-Cordum H., Ali J.,
RA   Carter J., Cordes M., Harris A., Isak A., van Brunt A., Nguyen C.,
RA   Du F., Courtney L., Kalicki J., Ozersky P., Abbott S., Armstrong J.,
RA   Belter E.A., Caruso L., Cedroni M., Cotton M., Davidson T., Desai A.,
RA   Elliott G., Erb T., Fronick C., Gaige T., Haakenson W., Haglund K.,
RA   Holmes A., Harkins R., Kim K., Kruchowski S.S., Strong C.M.,
RA   Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K.,
RA   McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C.,
RA   Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N.,
RA   Swearengen-Shahid S., Snider J., Strong J.T., Thompson J., Yoakum M.,
RA   Leonard S., Pearman C., Trani L., Radionenko M., Waligorski J.E.,
RA   Wang C., Rock S.M., Tin-Wollam A.-M., Maupin R., Latreille P.,
RA   Wendl M.C., Yang S.-P., Pohl C., Wallis J.W., Spieth J., Bieri T.A.,
RA   Berkowicz N., Nelson J.O., Osborne J., Ding L., Meyer R., Sabo A.,
RA   Shotland Y., Sinha P., Wohldmann P.E., Cook L.L., Hickenbotham M.T.,
RA   Eldred J., Williams D., Jones T.A., She X., Ciccarelli F.D.,
RA   Izaurralde E., Taylor J., Schmutz J., Myers R.M., Cox D.R., Huang X.,
RA   McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C.,
RA   Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S.,
RA   Miller W., Eichler E.E., Bork P., Suyama M., Torrents D.,
RA   Waterston R.H., Wilson R.K.;
RT   "Generation and annotation of the DNA sequences of human chromosomes 2
RT   and 4.";
RL   Nature 434:724-731(2005).
RN   [2] {ECO:0000313|Ensembl:ENSP00000407525}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JUL-2011) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Golgi apparatus membrane
CC       {ECO:0000256|RuleBase:RU364020}; Single-pass type II membrane
CC       protein {ECO:0000256|RuleBase:RU364020}.
CC   -!- SIMILARITY: Belongs to the sulfotransferase 2 family.
CC       {ECO:0000256|RuleBase:RU364020}.
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DR   EMBL; AC012493; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; C9JUE4; -.
DR   PeptideAtlas; C9JUE4; -.
DR   PRIDE; C9JUE4; -.
DR   Ensembl; ENST00000421474; ENSP00000407525; ENSG00000115526.
DR   UCSC; uc061mii.1; human.
DR   EuPathDB; HostDB:ENSG00000115526.10; -.
DR   HGNC; HGNC:19650; CHST10.
DR   OpenTargets; ENSG00000115526; -.
DR   eggNOG; KOG4651; Eukaryota.
DR   eggNOG; ENOG4111GJR; LUCA.
DR   GeneTree; ENSGT00940000157128; -.
DR   ChiTaRS; CHST10; human.
DR   Proteomes; UP000005640; Chromosome 2.
DR   Bgee; ENSG00000115526; Expressed in 180 organ(s), highest expression level in brain.
DR   ExpressionAtlas; C9JUE4; baseline and differential.
DR   GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:InterPro.
DR   GO; GO:0008146; F:sulfotransferase activity; IEA:InterPro.
DR   GO; GO:0016051; P:carbohydrate biosynthetic process; IEA:InterPro.
DR   InterPro; IPR018011; Carb_sulfotrans_8-10.
DR   PANTHER; PTHR12137; PTHR12137; 1.
PE   1: Evidence at protein level;
KW   Carbohydrate metabolism {ECO:0000256|RuleBase:RU364020};
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Glycoprotein {ECO:0000256|RuleBase:RU364020};
KW   Golgi apparatus {ECO:0000256|RuleBase:RU364020};
KW   Membrane {ECO:0000256|RuleBase:RU364020};
KW   Proteomics identification {ECO:0000213|PeptideAtlas:C9JUE4};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP};
KW   Signal-anchor {ECO:0000256|RuleBase:RU364020};
KW   Transferase {ECO:0000256|RuleBase:RU364020};
KW   Transmembrane {ECO:0000256|RuleBase:RU364020}.
FT   SIGNAL        1     21       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        22     85       Carbohydrate sulfotransferase.
FT                                {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5002997300.
FT   NON_TER      85     85       {ECO:0000313|Ensembl:ENSP00000407525}.
SQ   SEQUENCE   85 AA;  10098 MW;  DA719713D07DD238 CRC64;
     MHHQWLLLAA CFWVIFMFMV ASKFITLTFK DPDVYSAKQE FLFLTTMPEV RKLPEEKHIP
     EELKPTGKEL PDSQLVQPLV YMERL
//