ID   C9JR82_HUMAN            Unreviewed;       150 AA.
AC   C9JR82;
DT   03-NOV-2009, integrated into UniProtKB/TrEMBL.
DT   03-NOV-2009, sequence version 1.
DT   16-JAN-2019, entry version 46.
DE   SubName: Full=Complex I assembly factor TIMMDC1, mitochondrial {ECO:0000313|Ensembl:ENSP00000420122};
DE   Flags: Fragment;
GN   Name=TIMMDC1 {ECO:0000313|Ensembl:ENSP00000420122};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000420122, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000420122, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16641997; DOI=10.1038/nature04728;
RA   Muzny D.M., Scherer S.E., Kaul R., Wang J., Yu J., Sudbrak R.,
RA   Buhay C.J., Chen R., Cree A., Ding Y., Dugan-Rocha S., Gill R.,
RA   Gunaratne P., Harris R.A., Hawes A.C., Hernandez J., Hodgson A.V.,
RA   Hume J., Jackson A., Khan Z.M., Kovar-Smith C., Lewis L.R.,
RA   Lozado R.J., Metzker M.L., Milosavljevic A., Miner G.R., Morgan M.B.,
RA   Nazareth L.V., Scott G., Sodergren E., Song X.Z., Steffen D., Wei S.,
RA   Wheeler D.A., Wright M.W., Worley K.C., Yuan Y., Zhang Z., Adams C.Q.,
RA   Ansari-Lari M.A., Ayele M., Brown M.J., Chen G., Chen Z.,
RA   Clendenning J., Clerc-Blankenburg K.P., Chen R., Chen Z., Davis C.,
RA   Delgado O., Dinh H.H., Dong W., Draper H., Ernst S., Fu G.,
RA   Gonzalez-Garay M.L., Garcia D.K., Gillett W., Gu J., Hao B.,
RA   Haugen E., Havlak P., He X., Hennig S., Hu S., Huang W., Jackson L.R.,
RA   Jacob L.S., Kelly S.H., Kube M., Levy R., Li Z., Liu B., Liu J.,
RA   Liu W., Lu J., Maheshwari M., Nguyen B.V., Okwuonu G.O., Palmeiri A.,
RA   Pasternak S., Perez L.M., Phelps K.A., Plopper F.J., Qiang B.,
RA   Raymond C., Rodriguez R., Saenphimmachak C., Santibanez J., Shen H.,
RA   Shen Y., Subramanian S., Tabor P.E., Verduzco D., Waldron L., Wang J.,
RA   Wang J., Wang Q., Williams G.A., Wong G.K., Yao Z., Zhang J.,
RA   Zhang X., Zhao G., Zhou J., Zhou Y., Nelson D., Lehrach H.,
RA   Reinhardt R., Naylor S.L., Yang H., Olson M., Weinstock G.,
RA   Gibbs R.A.;
RT   "The DNA sequence, annotation and analysis of human chromosome 3.";
RL   Nature 440:1194-1198(2006).
RN   [2] {ECO:0000313|Ensembl:ENSP00000420122}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JUL-2011) to UniProtKB.
RN   [3] {ECO:0000213|PubMed:25944712}
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX   PubMed=25944712;
RA   Vaca Jacome A.S., Rabilloud T., Schaeffer-Reiss C., Rompais M.,
RA   Ayoub D., Lane L., Bairoch A., Van Dorsselaer A., Carapito C.;
RT   "N-terminome analysis of the human mitochondrial proteome.";
RL   Proteomics 15:2519-2524(2015).
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DR   EMBL; AC073352; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; C9JR82; -.
DR   EPD; C9JR82; -.
DR   jPOST; C9JR82; -.
DR   MaxQB; C9JR82; -.
DR   PeptideAtlas; C9JR82; -.
DR   PRIDE; C9JR82; -.
DR   Ensembl; ENST00000466984; ENSP00000420122; ENSG00000113845.
DR   UCSC; uc062muq.1; human.
DR   EuPathDB; HostDB:ENSG00000113845.9; -.
DR   HGNC; HGNC:1321; TIMMDC1.
DR   OpenTargets; ENSG00000113845; -.
DR   eggNOG; KOG4608; Eukaryota.
DR   eggNOG; ENOG4111F79; LUCA.
DR   GeneTree; ENSGT00390000013817; -.
DR   HOGENOM; HOG000111355; -.
DR   ChiTaRS; TIMMDC1; human.
DR   Proteomes; UP000005640; Chromosome 3.
DR   Bgee; ENSG00000113845; Expressed in 200 organ(s), highest expression level in left ventricle myocardium.
DR   ExpressionAtlas; C9JR82; baseline and differential.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Proteomics identification {ECO:0000213|EPD:C9JR82,
KW   ECO:0000213|MaxQB:C9JR82, ECO:0000213|PeptideAtlas:C9JR82};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   SIGNAL        1     24       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        25    150       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5002996588.
FT   TRANSMEM    103    124       Helical. {ECO:0000256|SAM:Phobius}.
FT   NON_TER     150    150       {ECO:0000313|Ensembl:ENSP00000420122}.
SQ   SEQUENCE   150 AA;  16660 MW;  34CC1E5BF01CD12B CRC64;
     MEVPPPAPRS FLCRALCLFP RVFAAEAVTA DSEVLEERQK RLPYVPEPYY PESGWDRLRE
     LFGKDTVNTS LNVYRNKDAL SHFVIAGAVT GSLFRINVGL RGLVAGGIIG ALLGTPVGGL
     LMAFQKYSGE TVQERKQKDR KALHELKLEE
//