ID   C9JQX7_HUMAN            Unreviewed;        87 AA.
AC   C9JQX7;
DT   03-NOV-2009, integrated into UniProtKB/TrEMBL.
DT   03-NOV-2009, sequence version 1.
DT   16-JAN-2019, entry version 59.
DE   SubName: Full=EGF-containing fibulin-like extracellular matrix protein 1 {ECO:0000313|Ensembl:ENSP00000389319};
DE   Flags: Fragment;
GN   Name=EFEMP1 {ECO:0000313|Ensembl:ENSP00000389319};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000389319, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000389319, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15815621; DOI=10.1038/nature03466;
RA   Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H.,
RA   Minx P., Wagner-McPherson C., Layman D., Wylie K., Sekhon M.,
RA   Becker M.C., Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E.,
RA   Kremitzki C., Oddy L., Du H., Sun H., Bradshaw-Cordum H., Ali J.,
RA   Carter J., Cordes M., Harris A., Isak A., van Brunt A., Nguyen C.,
RA   Du F., Courtney L., Kalicki J., Ozersky P., Abbott S., Armstrong J.,
RA   Belter E.A., Caruso L., Cedroni M., Cotton M., Davidson T., Desai A.,
RA   Elliott G., Erb T., Fronick C., Gaige T., Haakenson W., Haglund K.,
RA   Holmes A., Harkins R., Kim K., Kruchowski S.S., Strong C.M.,
RA   Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K.,
RA   McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C.,
RA   Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N.,
RA   Swearengen-Shahid S., Snider J., Strong J.T., Thompson J., Yoakum M.,
RA   Leonard S., Pearman C., Trani L., Radionenko M., Waligorski J.E.,
RA   Wang C., Rock S.M., Tin-Wollam A.-M., Maupin R., Latreille P.,
RA   Wendl M.C., Yang S.-P., Pohl C., Wallis J.W., Spieth J., Bieri T.A.,
RA   Berkowicz N., Nelson J.O., Osborne J., Ding L., Meyer R., Sabo A.,
RA   Shotland Y., Sinha P., Wohldmann P.E., Cook L.L., Hickenbotham M.T.,
RA   Eldred J., Williams D., Jones T.A., She X., Ciccarelli F.D.,
RA   Izaurralde E., Taylor J., Schmutz J., Myers R.M., Cox D.R., Huang X.,
RA   McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C.,
RA   Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S.,
RA   Miller W., Eichler E.E., Bork P., Suyama M., Torrents D.,
RA   Waterston R.H., Wilson R.K.;
RT   "Generation and annotation of the DNA sequences of human chromosomes 2
RT   and 4.";
RL   Nature 434:724-731(2005).
RN   [2] {ECO:0000313|Ensembl:ENSP00000389319}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JUL-2011) to UniProtKB.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   -----------------------------------------------------------------------
DR   EMBL; AC010895; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC096549; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; C9JQX7; -.
DR   jPOST; C9JQX7; -.
DR   MaxQB; C9JQX7; -.
DR   PeptideAtlas; C9JQX7; -.
DR   PRIDE; C9JQX7; -.
DR   Ensembl; ENST00000429909; ENSP00000389319; ENSG00000115380.
DR   UCSC; uc061jix.1; human.
DR   EuPathDB; HostDB:ENSG00000115380.19; -.
DR   HGNC; HGNC:3218; EFEMP1.
DR   OpenTargets; ENSG00000115380; -.
DR   eggNOG; ENOG410IR77; Eukaryota.
DR   eggNOG; ENOG410YCRW; LUCA.
DR   GeneTree; ENSGT00940000157837; -.
DR   ChiTaRS; EFEMP1; human.
DR   Proteomes; UP000005640; Chromosome 2.
DR   Bgee; ENSG00000115380; Expressed in 226 organ(s), highest expression level in thoracic aorta.
DR   ExpressionAtlas; C9JQX7; baseline and differential.
DR   GO; GO:0062023; C:collagen-containing extracellular matrix; IEA:InterPro.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0005006; F:epidermal growth factor-activated receptor activity; IEA:InterPro.
DR   InterPro; IPR032973; EFEMP1.
DR   InterPro; IPR001881; EGF-like_Ca-bd_dom.
DR   InterPro; IPR018097; EGF_Ca-bd_CS.
DR   InterPro; IPR037287; Fibulin_3/4/5.
DR   PANTHER; PTHR44074; PTHR44074; 1.
DR   PANTHER; PTHR44074:SF2; PTHR44074:SF2; 1.
DR   Pfam; PF07645; EGF_CA; 1.
DR   PROSITE; PS01187; EGF_CA; 1.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Proteomics identification {ECO:0000213|MaxQB:C9JQX7,
KW   ECO:0000213|PeptideAtlas:C9JQX7};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     17       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        18     87       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5002997430.
FT   DOMAIN       44     71       EGF_CA. {ECO:0000259|Pfam:PF07645}.
FT   NON_TER      87     87       {ECO:0000313|Ensembl:ENSP00000389319}.
SQ   SEQUENCE   87 AA;  9847 MW;  8191CA0954778A00 CRC64;
     MLKALFLTML TLALVKSQDT EETITYTQCT DGYEWDPVRQ QCKDIDECDI VPDACKGGMK
     CVNHYGGYLC LPKTAQIIVN NEQPQQE
//