ID   C9JQA6_HUMAN            Unreviewed;       166 AA.
AC   C9JQA6;
DT   03-NOV-2009, integrated into UniProtKB/TrEMBL.
DT   21-SEP-2011, sequence version 2.
DT   05-DEC-2018, entry version 66.
DE   SubName: Full=Zinc finger protein 433 {ECO:0000313|Ensembl:ENSP00000414857};
DE   Flags: Fragment;
GN   Name=ZNF433 {ECO:0000313|Ensembl:ENSP00000414857};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000414857, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000414857, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15057824; DOI=10.1038/nature02399;
RA   Grimwood J., Gordon L.A., Olsen A.S., Terry A., Schmutz J.,
RA   Lamerdin J.E., Hellsten U., Goodstein D., Couronne O., Tran-Gyamfi M.,
RA   Aerts A., Altherr M., Ashworth L., Bajorek E., Black S., Branscomb E.,
RA   Caenepeel S., Carrano A.V., Caoile C., Chan Y.M., Christensen M.,
RA   Cleland C.A., Copeland A., Dalin E., Dehal P., Denys M., Detter J.C.,
RA   Escobar J., Flowers D., Fotopulos D., Garcia C., Georgescu A.M.,
RA   Glavina T., Gomez M., Gonzales E., Groza M., Hammon N., Hawkins T.,
RA   Haydu L., Ho I., Huang W., Israni S., Jett J., Kadner K., Kimball H.,
RA   Kobayashi A., Larionov V., Leem S.-H., Lopez F., Lou Y., Lowry S.,
RA   Malfatti S., Martinez D., McCready P.M., Medina C., Morgan J.,
RA   Nelson K., Nolan M., Ovcharenko I., Pitluck S., Pollard M.,
RA   Popkie A.P., Predki P., Quan G., Ramirez L., Rash S., Retterer J.,
RA   Rodriguez A., Rogers S., Salamov A., Salazar A., She X., Smith D.,
RA   Slezak T., Solovyev V., Thayer N., Tice H., Tsai M., Ustaszewska A.,
RA   Vo N., Wagner M., Wheeler J., Wu K., Xie G., Yang J., Dubchak I.,
RA   Furey T.S., DeJong P., Dickson M., Gordon D., Eichler E.E.,
RA   Pennacchio L.A., Richardson P., Stubbs L., Rokhsar D.S., Myers R.M.,
RA   Rubin E.M., Lucas S.M.;
RT   "The DNA sequence and biology of human chromosome 19.";
RL   Nature 428:529-535(2004).
RN   [2] {ECO:0000313|Ensembl:ENSP00000414857}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JUL-2011) to UniProtKB.
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DR   EMBL; AC008770; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC022415; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; KC877701; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; C9JQA6; -.
DR   MaxQB; C9JQA6; -.
DR   PRIDE; C9JQA6; -.
DR   Ensembl; ENST00000455504; ENSP00000414857; ENSG00000197647.
DR   UCSC; uc060twq.1; human.
DR   EuPathDB; HostDB:ENSG00000197647.11; -.
DR   HGNC; HGNC:20811; ZNF433.
DR   OpenTargets; ENSG00000197647; -.
DR   PharmGKB; PA134943717; -.
DR   eggNOG; KOG1721; Eukaryota.
DR   eggNOG; COG5048; LUCA.
DR   GeneTree; ENSGT00940000153317; -.
DR   HOGENOM; HOG000234617; -.
DR   Proteomes; UP000005640; Chromosome 19.
DR   Bgee; ENSG00000197647; Expressed in 91 organ(s), highest expression level in testis.
DR   ExpressionAtlas; C9JQA6; baseline and differential.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   CDD; cd07765; KRAB_A-box; 1.
DR   InterPro; IPR001909; KRAB.
DR   InterPro; IPR036051; KRAB_dom_sf.
DR   Pfam; PF01352; KRAB; 1.
DR   SMART; SM00349; KRAB; 1.
DR   SUPFAM; SSF109640; SSF109640; 1.
DR   PROSITE; PS50805; KRAB; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     19       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        20    166       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5002996491.
FT   DOMAIN       18     96       KRAB. {ECO:0000259|PROSITE:PS50805}.
FT   NON_TER     166    166       {ECO:0000313|Ensembl:ENSP00000414857}.
SQ   SEQUENCE   166 AA;  19272 MW;  12C3A39DB3D3350C CRC64;
     MLVLSILLYT CEMFQDSVAF EDVAVTFTQE EWALLDPSQK NLCRDVMQET FRNLASIGKK
     WKPQNIYVEY ENLRRNLRIV GERLFESKEG HQHGEILTQV PDDMLKKTTT GVKSCESSVY
     GEVGSAHSSL NRHIRDDTGH KAYEYQEYGQ KPYKCKYCKK PFNCLS
//