ID   C9JIG4_HUMAN            Unreviewed;       114 AA.
AC   C9JIG4;
DT   03-NOV-2009, integrated into UniProtKB/TrEMBL.
DT   03-NOV-2009, sequence version 1.
DT   16-JAN-2019, entry version 56.
DE   SubName: Full=Prolyl 4-hydroxylase subunit alpha-2 {ECO:0000313|Ensembl:ENSP00000403883};
DE   Flags: Fragment;
GN   Name=P4HA2 {ECO:0000313|Ensembl:ENSP00000403883};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000403883, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000403883, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15372022; DOI=10.1038/nature02919;
RA   Schmutz J., Martin J., Terry A., Couronne O., Grimwood J., Lowry S.,
RA   Gordon L.A., Scott D., Xie G., Huang W., Hellsten U., Tran-Gyamfi M.,
RA   She X., Prabhakar S., Aerts A., Altherr M., Bajorek E., Black S.,
RA   Branscomb E., Caoile C., Challacombe J.F., Chan Y.M., Denys M.,
RA   Detter J.C., Escobar J., Flowers D., Fotopulos D., Glavina T.,
RA   Gomez M., Gonzales E., Goodstein D., Grigoriev I., Groza M.,
RA   Hammon N., Hawkins T., Haydu L., Israni S., Jett J., Kadner K.,
RA   Kimball H., Kobayashi A., Lopez F., Lou Y., Martinez D., Medina C.,
RA   Morgan J., Nandkeshwar R., Noonan J.P., Pitluck S., Pollard M.,
RA   Predki P., Priest J., Ramirez L., Retterer J., Rodriguez A.,
RA   Rogers S., Salamov A., Salazar A., Thayer N., Tice H., Tsai M.,
RA   Ustaszewska A., Vo N., Wheeler J., Wu K., Yang J., Dickson M.,
RA   Cheng J.-F., Eichler E.E., Olsen A., Pennacchio L.A., Rokhsar D.S.,
RA   Richardson P., Lucas S.M., Myers R.M., Rubin E.M.;
RT   "The DNA sequence and comparative analysis of human chromosome 5.";
RL   Nature 431:268-274(2004).
RN   [2] {ECO:0000313|Ensembl:ENSP00000403883}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JUL-2011) to UniProtKB.
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DR   EMBL; AC034220; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC063976; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; KC877101; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; C9JIG4; -.
DR   jPOST; C9JIG4; -.
DR   MaxQB; C9JIG4; -.
DR   PeptideAtlas; C9JIG4; -.
DR   PRIDE; C9JIG4; -.
DR   Ensembl; ENST00000418055; ENSP00000403883; ENSG00000072682.
DR   UCSC; uc063gtu.1; human.
DR   EuPathDB; HostDB:ENSG00000072682.18; -.
DR   HGNC; HGNC:8547; P4HA2.
DR   OpenTargets; ENSG00000072682; -.
DR   eggNOG; KOG1591; Eukaryota.
DR   eggNOG; ENOG410XS5J; LUCA.
DR   GeneTree; ENSGT00940000157695; -.
DR   ChiTaRS; P4HA2; human.
DR   Proteomes; UP000005640; Chromosome 5.
DR   Bgee; ENSG00000072682; Expressed in 211 organ(s), highest expression level in tibia.
DR   ExpressionAtlas; C9JIG4; baseline and differential.
DR   GO; GO:0005783; C:endoplasmic reticulum; IEA:InterPro.
DR   GO; GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:InterPro.
DR   GO; GO:0004656; F:procollagen-proline 4-dioxygenase activity; IEA:InterPro.
DR   InterPro; IPR013547; Pro_4_hyd_alph_N.
DR   Pfam; PF08336; P4Ha_N; 1.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Proteomics identification {ECO:0000213|EPD:C9JIG4,
KW   ECO:0000213|MaxQB:C9JIG4, ECO:0000213|PeptideAtlas:C9JIG4};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     21       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        22    114       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5002996440.
FT   DOMAIN       26    112       P4Ha_N. {ECO:0000259|Pfam:PF08336}.
FT   NON_TER     114    114       {ECO:0000313|Ensembl:ENSP00000403883}.
SQ   SEQUENCE   114 AA;  12726 MW;  12661B588814BC9B CRC64;
     MKLWVSALLM AWFGVLSCVQ AEFFTSIGHM TDLIYAEKEL VQSLKEYILV EEAKLSKIKS
     WANKMEALTS KSAADAEGYL AHPVNAYKLV KRLNTDWPAL EDLVLQDSAA GFIA
//