ID   C9JIE7_HUMAN            Unreviewed;       148 AA.
AC   C9JIE7;
DT   03-NOV-2009, integrated into UniProtKB/TrEMBL.
DT   03-NOV-2009, sequence version 1.
DT   16-JAN-2019, entry version 63.
DE   SubName: Full=Endothelial cell-selective adhesion molecule {ECO:0000313|Ensembl:ENSP00000415893};
DE   Flags: Fragment;
GN   Name=ESAM {ECO:0000313|Ensembl:ENSP00000415893};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000415893, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000415893, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16554811; DOI=10.1038/nature04632;
RA   Taylor T.D., Noguchi H., Totoki Y., Toyoda A., Kuroki Y., Dewar K.,
RA   Lloyd C., Itoh T., Takeda T., Kim D.W., She X., Barlow K.F., Bloom T.,
RA   Bruford E., Chang J.L., Cuomo C.A., Eichler E., FitzGerald M.G.,
RA   Jaffe D.B., LaButti K., Nicol R., Park H.S., Seaman C., Sougnez C.,
RA   Yang X., Zimmer A.R., Zody M.C., Birren B.W., Nusbaum C., Fujiyama A.,
RA   Hattori M., Rogers J., Lander E.S., Sakaki Y.;
RT   "Human chromosome 11 DNA sequence and analysis including novel gene
RT   identification.";
RL   Nature 440:497-500(2006).
RN   [2] {ECO:0000313|Ensembl:ENSP00000415893}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JUL-2011) to UniProtKB.
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DR   EMBL; AP000866; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; C9JIE7; -.
DR   jPOST; C9JIE7; -.
DR   PeptideAtlas; C9JIE7; -.
DR   PRIDE; C9JIE7; -.
DR   Ensembl; ENST00000435477; ENSP00000415893; ENSG00000149564.
DR   UCSC; uc058irk.1; human.
DR   EuPathDB; HostDB:ENSG00000149564.11; -.
DR   HGNC; HGNC:17474; ESAM.
DR   OpenTargets; ENSG00000149564; -.
DR   eggNOG; ENOG410IHVB; Eukaryota.
DR   eggNOG; ENOG4111DT8; LUCA.
DR   GeneTree; ENSGT00940000157231; -.
DR   HOGENOM; HOG000111222; -.
DR   Proteomes; UP000005640; Chromosome 11.
DR   Bgee; ENSG00000149564; Expressed in 178 organ(s), highest expression level in prostate gland.
DR   ExpressionAtlas; C9JIE7; baseline and differential.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.40.10; -; 1.
DR   InterPro; IPR007110; Ig-like_dom.
DR   InterPro; IPR036179; Ig-like_dom_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR003599; Ig_sub.
DR   InterPro; IPR003598; Ig_sub2.
DR   SMART; SM00409; IG; 1.
DR   SMART; SM00408; IGc2; 1.
DR   SUPFAM; SSF48726; SSF48726; 1.
DR   PROSITE; PS50835; IG_LIKE; 1.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Proteomics identification {ECO:0000213|MaxQB:C9JIE7,
KW   ECO:0000213|PeptideAtlas:C9JIE7};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   SIGNAL        1     22       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        23    148       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5002997392.
FT   TRANSMEM    120    144       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       40    115       Ig-like. {ECO:0000259|PROSITE:PS50835}.
FT   NON_TER     148    148       {ECO:0000313|Ensembl:ENSP00000415893}.
SQ   SEQUENCE   148 AA;  15392 MW;  662109875B495598 CRC64;
     MISLPGPLVT NLLRFLFLGL SALVPPAPPS CRLQGVPHVG ANVTLSCQSP RSKPAVQYQW
     DRQLPSFQTF FAPALDVIRG SLSLTNLSSS MAGVYVCKAH NEVGTAQCNV TLEVSTGPGA
     AVVAGAVVGT LVGLGLLAGL VLLYHRRG
//