ID   C9JHH6_HUMAN            Unreviewed;       142 AA.
AC   C9JHH6;
DT   03-NOV-2009, integrated into UniProtKB/TrEMBL.
DT   05-OCT-2016, sequence version 8.
DT   16-JAN-2019, entry version 64.
DE   SubName: Full=Probable ribonuclease 11 {ECO:0000313|Ensembl:ENSP00000415954};
DE   Flags: Fragment;
GN   Name=RNASE11 {ECO:0000313|Ensembl:ENSP00000415954};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000415954, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000415954, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=12508121; DOI=10.1038/nature01348;
RA   Heilig R., Eckenberg R., Petit J.-L., Fonknechten N., Da Silva C.,
RA   Cattolico L., Levy M., Barbe V., De Berardinis V., Ureta-Vidal A.,
RA   Pelletier E., Vico V., Anthouard V., Rowen L., Madan A., Qin S.,
RA   Sun H., Du H., Pepin K., Artiguenave F., Robert C., Cruaud C.,
RA   Bruels T., Jaillon O., Friedlander L., Samson G., Brottier P.,
RA   Cure S., Segurens B., Aniere F., Samain S., Crespeau H., Abbasi N.,
RA   Aiach N., Boscus D., Dickhoff R., Dors M., Dubois I., Friedman C.,
RA   Gouyvenoux M., James R., Madan A., Mairey-Estrada B., Mangenot S.,
RA   Martins N., Menard M., Oztas S., Ratcliffe A., Shaffer T., Trask B.,
RA   Vacherie B., Bellemere C., Belser C., Besnard-Gonnet M.,
RA   Bartol-Mavel D., Boutard M., Briez-Silla S., Combette S.,
RA   Dufosse-Laurent V., Ferron C., Lechaplais C., Louesse C., Muselet D.,
RA   Magdelenat G., Pateau E., Petit E., Sirvain-Trukniewicz P., Trybou A.,
RA   Vega-Czarny N., Bataille E., Bluet E., Bordelais I., Dubois M.,
RA   Dumont C., Guerin T., Haffray S., Hammadi R., Muanga J., Pellouin V.,
RA   Robert D., Wunderle E., Gauguet G., Roy A., Sainte-Marthe L.,
RA   Verdier J., Verdier-Discala C., Hillier L.W., Fulton L., McPherson J.,
RA   Matsuda F., Wilson R., Scarpelli C., Gyapay G., Wincker P., Saurin W.,
RA   Quetier F., Waterston R., Hood L., Weissenbach J.;
RT   "The DNA sequence and analysis of human chromosome 14.";
RL   Nature 421:601-607(2003).
RN   [2] {ECO:0000313|Ensembl:ENSP00000415954}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JUL-2011) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the pancreatic ribonuclease family.
CC       {ECO:0000256|SAAS:SAAS00686975}.
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DR   EMBL; AL163195; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; C9JHH6; -.
DR   jPOST; C9JHH6; -.
DR   PRIDE; C9JHH6; -.
DR   Ensembl; ENST00000413502; ENSP00000415954; ENSG00000173464.
DR   UCSC; uc058yuo.1; human.
DR   EuPathDB; HostDB:ENSG00000173464.14; -.
DR   HGNC; HGNC:19269; RNASE11.
DR   eggNOG; ENOG410IY14; Eukaryota.
DR   eggNOG; ENOG4111CPE; LUCA.
DR   GeneTree; ENSGT00510000049471; -.
DR   HOGENOM; HOG000137920; -.
DR   Proteomes; UP000005640; Chromosome 14.
DR   Bgee; ENSG00000173464; Expressed in 28 organ(s), highest expression level in right testis.
DR   ExpressionAtlas; C9JHH6; baseline.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   Gene3D; 3.10.130.10; -; 1.
DR   InterPro; IPR029743; RNASE11.
DR   InterPro; IPR001427; RNaseA.
DR   InterPro; IPR036816; RNaseA-like_dom_sf.
DR   PANTHER; PTHR11437; PTHR11437; 1.
DR   PANTHER; PTHR11437:SF22; PTHR11437:SF22; 1.
DR   SUPFAM; SSF54076; SSF54076; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     18       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        19    142       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5008412930.
FT   NON_TER     142    142       {ECO:0000313|Ensembl:ENSP00000415954}.
SQ   SEQUENCE   142 AA;  16139 MW;  95A1EC3539E4C178 CRC64;
     METFPLLLLS LGLVLAEASE STMKIIKEEF TDEEMQYDMA KSGQEKQTIE ILMNPILLVK
     NTSLSMSKDD MSSTLLTFRS LHYNDPKGNS SGNDKECCND MTVWRKVSEA NGSCKWSNNF
     IRSSTEVMRR VHRAPSCKFV QN
//