ID   C9JH44_HUMAN            Unreviewed;       180 AA.
AC   C9JH44;
DT   03-NOV-2009, integrated into UniProtKB/TrEMBL.
DT   03-NOV-2009, sequence version 1.
DT   16-JAN-2019, entry version 61.
DE   SubName: Full=Collagen alpha-2(VI) chain {ECO:0000313|Ensembl:ENSP00000390418};
DE   Flags: Fragment;
GN   Name=COL6A2 {ECO:0000313|Ensembl:ENSP00000390418};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000390418, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000390418, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=10830953; DOI=10.1038/35012518;
RG   Chromosome 21 mapping and sequencing consortium;
RA   Hattori M., Fujiyama A., Taylor T.D., Watanabe H., Yada T.,
RA   Park H.-S., Toyoda A., Ishii K., Totoki Y., Choi D.-K., Groner Y.,
RA   Soeda E., Ohki M., Takagi T., Sakaki Y., Taudien S., Blechschmidt K.,
RA   Polley A., Menzel U., Delabar J., Kumpf K., Lehmann R., Patterson D.,
RA   Reichwald K., Rump A., Schillhabel M., Schudy A., Zimmermann W.,
RA   Rosenthal A., Kudoh J., Shibuya K., Kawasaki K., Asakawa S.,
RA   Shintani A., Sasaki T., Nagamine K., Mitsuyama S., Antonarakis S.E.,
RA   Minoshima S., Shimizu N., Nordsiek G., Hornischer K., Brandt P.,
RA   Scharfe M., Schoen O., Desario A., Reichelt J., Kauer G., Bloecker H.,
RA   Ramser J., Beck A., Klages S., Hennig S., Riesselmann L., Dagand E.,
RA   Wehrmeyer S., Borzym K., Gardiner K., Nizetic D., Francis F.,
RA   Lehrach H., Reinhardt R., Yaspo M.-L.;
RT   "The DNA sequence of human chromosome 21.";
RL   Nature 405:311-319(2000).
RN   [2] {ECO:0000313|Ensembl:ENSP00000390418}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JUL-2011) to UniProtKB.
RN   [3] {ECO:0000213|PubMed:24275569}
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX   PubMed=24275569; DOI=10.1016/j.jprot.2013.11.014;
RA   Bian Y., Song C., Cheng K., Dong M., Wang F., Huang J., Sun D.,
RA   Wang L., Ye M., Zou H.;
RT   "An enzyme assisted RP-RPLC approach for in-depth analysis of human
RT   liver phosphoproteome.";
RL   J. Proteomics 96:253-262(2014).
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DR   EMBL; AP001101; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AP001467; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AP001471; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; C9JH44; -.
DR   jPOST; C9JH44; -.
DR   MaxQB; C9JH44; -.
DR   PeptideAtlas; C9JH44; -.
DR   PRIDE; C9JH44; -.
DR   Ensembl; ENST00000436769; ENSP00000390418; ENSG00000142173.
DR   UCSC; uc062axy.1; human.
DR   EuPathDB; HostDB:ENSG00000142173.14; -.
DR   HGNC; HGNC:2212; COL6A2.
DR   OpenTargets; ENSG00000142173; -.
DR   eggNOG; ENOG410IS7F; Eukaryota.
DR   eggNOG; ENOG410XT53; LUCA.
DR   GeneTree; ENSGT00940000155682; -.
DR   HOGENOM; HOG000111863; -.
DR   ChiTaRS; COL6A2; human.
DR   Proteomes; UP000005640; Chromosome 21.
DR   Bgee; ENSG00000142173; Expressed in 211 organ(s), highest expression level in esophagogastric junction muscularis propria.
DR   ExpressionAtlas; C9JH44; baseline and differential.
DR   Gene3D; 3.40.50.410; -; 1.
DR   InterPro; IPR002035; VWF_A.
DR   InterPro; IPR036465; vWFA_dom_sf.
DR   Pfam; PF00092; VWA; 1.
DR   SUPFAM; SSF53300; SSF53300; 1.
DR   PROSITE; PS50234; VWFA; 1.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Proteomics identification {ECO:0000213|MaxQB:C9JH44,
KW   ECO:0000213|PeptideAtlas:C9JH44};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     20       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        21    180       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5002997733.
FT   DOMAIN       46    180       VWFA. {ECO:0000259|PROSITE:PS50234}.
FT   NON_TER     180    180       {ECO:0000313|Ensembl:ENSP00000390418}.
SQ   SEQUENCE   180 AA;  20044 MW;  7F4DA54E7F8A9191 CRC64;
     MLQGTCSVLL LWGILGAIQA QQQEVISPDT TERNNNCPEK TDCPIHVYFV LDTSESVTMQ
     SPTDILLFHM KQFVPQFISQ LQNEFYLDQV ALSWRYGGLH FSDQVEVFSP PGSDRASFIK
     NLQGISSFRR GTFTDCALAN MTEQIRQDRS KGTVHFAVVI TDGHVTGSPC GGIKLQAERA
//