ID   C9JH43_HUMAN            Unreviewed;       431 AA.
AC   C9JH43;
DT   03-NOV-2009, integrated into UniProtKB/TrEMBL.
DT   03-NOV-2009, sequence version 1.
DT   05-DEC-2018, entry version 59.
DE   SubName: Full=Neuronal cell adhesion molecule {ECO:0000313|Ensembl:ENSP00000390421};
DE   Flags: Fragment;
GN   Name=NRCAM {ECO:0000313|Ensembl:ENSP00000390421};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000390421, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000390421, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=12853948; DOI=10.1038/nature01782;
RA   Hillier L.W., Fulton R.S., Fulton L.A., Graves T.A., Pepin K.H.,
RA   Wagner-McPherson C., Layman D., Maas J., Jaeger S., Walker R.,
RA   Wylie K., Sekhon M., Becker M.C., O'Laughlin M.D., Schaller M.E.,
RA   Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E., Cordes M., Du H.,
RA   Sun H., Edwards J., Bradshaw-Cordum H., Ali J., Andrews S., Isak A.,
RA   Vanbrunt A., Nguyen C., Du F., Lamar B., Courtney L., Kalicki J.,
RA   Ozersky P., Bielicki L., Scott K., Holmes A., Harkins R., Harris A.,
RA   Strong C.M., Hou S., Tomlinson C., Dauphin-Kohlberg S.,
RA   Kozlowicz-Reilly A., Leonard S., Rohlfing T., Rock S.M.,
RA   Tin-Wollam A.-M., Abbott A., Minx P., Maupin R., Strowmatt C.,
RA   Latreille P., Miller N., Johnson D., Murray J., Woessner J.P.,
RA   Wendl M.C., Yang S.-P., Schultz B.R., Wallis J.W., Spieth J.,
RA   Bieri T.A., Nelson J.O., Berkowicz N., Wohldmann P.E., Cook L.L.,
RA   Hickenbotham M.T., Eldred J., Williams D., Bedell J.A., Mardis E.R.,
RA   Clifton S.W., Chissoe S.L., Marra M.A., Raymond C., Haugen E.,
RA   Gillett W., Zhou Y., James R., Phelps K., Iadanoto S., Bubb K.,
RA   Simms E., Levy R., Clendenning J., Kaul R., Kent W.J., Furey T.S.,
RA   Baertsch R.A., Brent M.R., Keibler E., Flicek P., Bork P., Suyama M.,
RA   Bailey J.A., Portnoy M.E., Torrents D., Chinwalla A.T., Gish W.R.,
RA   Eddy S.R., McPherson J.D., Olson M.V., Eichler E.E., Green E.D.,
RA   Waterston R.H., Wilson R.K.;
RT   "The DNA sequence of human chromosome 7.";
RL   Nature 424:157-164(2003).
RN   [2] {ECO:0000313|Ensembl:ENSP00000390421}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JUL-2011) to UniProtKB.
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DR   EMBL; AC005058; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC005683; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC007567; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; KF510970; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; C9JH43; -.
DR   MaxQB; C9JH43; -.
DR   PeptideAtlas; C9JH43; -.
DR   PRIDE; C9JH43; -.
DR   Ensembl; ENST00000417701; ENSP00000390421; ENSG00000091129.
DR   UCSC; uc064hba.1; human.
DR   EuPathDB; HostDB:ENSG00000091129.19; -.
DR   HGNC; HGNC:7994; NRCAM.
DR   OpenTargets; ENSG00000091129; -.
DR   eggNOG; KOG3513; Eukaryota.
DR   eggNOG; ENOG410XSVG; LUCA.
DR   GeneTree; ENSGT00940000155419; -.
DR   HOGENOM; HOG000231380; -.
DR   ChiTaRS; NRCAM; human.
DR   Proteomes; UP000005640; Chromosome 7.
DR   Bgee; ENSG00000091129; Expressed in 186 organ(s), highest expression level in middle temporal gyrus.
DR   ExpressionAtlas; C9JH43; baseline and differential.
DR   Gene3D; 2.60.40.10; -; 4.
DR   InterPro; IPR007110; Ig-like_dom.
DR   InterPro; IPR036179; Ig-like_dom_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR013098; Ig_I-set.
DR   InterPro; IPR003599; Ig_sub.
DR   InterPro; IPR003598; Ig_sub2.
DR   Pfam; PF07679; I-set; 1.
DR   SMART; SM00409; IG; 4.
DR   SMART; SM00408; IGc2; 4.
DR   SUPFAM; SSF48726; SSF48726; 4.
DR   PROSITE; PS50835; IG_LIKE; 4.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Proteomics identification {ECO:0000213|MaxQB:C9JH43,
KW   ECO:0000213|PeptideAtlas:C9JH43};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     29       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        30    431       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5002996438.
FT   DOMAIN       40    128       Ig-like. {ECO:0000259|PROSITE:PS50835}.
FT   DOMAIN      135    229       Ig-like. {ECO:0000259|PROSITE:PS50835}.
FT   DOMAIN      261    350       Ig-like. {ECO:0000259|PROSITE:PS50835}.
FT   DOMAIN      355    431       Ig-like. {ECO:0000259|PROSITE:PS50835}.
FT   NON_TER     431    431       {ECO:0000313|Ensembl:ENSP00000390421}.
SQ   SEQUENCE   431 AA;  47981 MW;  D0CF1BBE4F0BA3E9 CRC64;
     MQLKIMPKKK RLSAGRVPLI LFLCQMISAL EVPLDLVQPP TITQQSPKDY IIDPRENIVI
     QCEAKGKPPP SFSWTRNGTH FDIDKDPLVT MKPGTGTLII NIMSEGKAET YEGVYQCTAR
     NERGAAVSNN IVVRPSRSPL WTKEKLEPIT LQSGQSLVLP CRPPIGLPPP IIFWMDNSFQ
     RLPQSERVSQ GLNGDLYFSN VLPEDTREDY ICYARFNHTQ TIQQKQPISV KVISVDELND
     TIAANLSDTE FYGAKSSRER PPTFLTPEGN ASNKEELRGN VLSLECIAEG LPTPIIYWAK
     EDGMLPKNRT VYKNFEKTLQ IIHVSEADSG NYQCIAKNAL GAIHHTISVR VKAAPYWITA
     PQNLVLSPGE DGTLICRANG NPKPRISWLT NGVPIEIAPD DPSRKIDGDT IIFSNVQERS
     SAVYQCNASN E
//