ID   C9JF17_HUMAN            Unreviewed;       215 AA.
AC   C9JF17;
DT   03-NOV-2009, integrated into UniProtKB/TrEMBL.
DT   03-NOV-2009, sequence version 1.
DT   16-JAN-2019, entry version 70.
DE   SubName: Full=Apolipoprotein D {ECO:0000313|Ensembl:ENSP00000415235};
DE   Flags: Fragment;
GN   Name=APOD {ECO:0000313|Ensembl:ENSP00000415235};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000415235, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000415235, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16641997; DOI=10.1038/nature04728;
RA   Muzny D.M., Scherer S.E., Kaul R., Wang J., Yu J., Sudbrak R.,
RA   Buhay C.J., Chen R., Cree A., Ding Y., Dugan-Rocha S., Gill R.,
RA   Gunaratne P., Harris R.A., Hawes A.C., Hernandez J., Hodgson A.V.,
RA   Hume J., Jackson A., Khan Z.M., Kovar-Smith C., Lewis L.R.,
RA   Lozado R.J., Metzker M.L., Milosavljevic A., Miner G.R., Morgan M.B.,
RA   Nazareth L.V., Scott G., Sodergren E., Song X.Z., Steffen D., Wei S.,
RA   Wheeler D.A., Wright M.W., Worley K.C., Yuan Y., Zhang Z., Adams C.Q.,
RA   Ansari-Lari M.A., Ayele M., Brown M.J., Chen G., Chen Z.,
RA   Clendenning J., Clerc-Blankenburg K.P., Chen R., Chen Z., Davis C.,
RA   Delgado O., Dinh H.H., Dong W., Draper H., Ernst S., Fu G.,
RA   Gonzalez-Garay M.L., Garcia D.K., Gillett W., Gu J., Hao B.,
RA   Haugen E., Havlak P., He X., Hennig S., Hu S., Huang W., Jackson L.R.,
RA   Jacob L.S., Kelly S.H., Kube M., Levy R., Li Z., Liu B., Liu J.,
RA   Liu W., Lu J., Maheshwari M., Nguyen B.V., Okwuonu G.O., Palmeiri A.,
RA   Pasternak S., Perez L.M., Phelps K.A., Plopper F.J., Qiang B.,
RA   Raymond C., Rodriguez R., Saenphimmachak C., Santibanez J., Shen H.,
RA   Shen Y., Subramanian S., Tabor P.E., Verduzco D., Waldron L., Wang J.,
RA   Wang J., Wang Q., Williams G.A., Wong G.K., Yao Z., Zhang J.,
RA   Zhang X., Zhao G., Zhou J., Zhou Y., Nelson D., Lehrach H.,
RA   Reinhardt R., Naylor S.L., Yang H., Olson M., Weinstock G.,
RA   Gibbs R.A.;
RT   "The DNA sequence, annotation and analysis of human chromosome 3.";
RL   Nature 440:1194-1198(2006).
RN   [2] {ECO:0000313|Ensembl:ENSP00000415235}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JUL-2011) to UniProtKB.
RN   [3] {ECO:0000213|PubMed:24275569}
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX   PubMed=24275569; DOI=10.1016/j.jprot.2013.11.014;
RA   Bian Y., Song C., Cheng K., Dong M., Wang F., Huang J., Sun D.,
RA   Wang L., Ye M., Zou H.;
RT   "An enzyme assisted RP-RPLC approach for in-depth analysis of human
RT   liver phosphoproteome.";
RL   J. Proteomics 96:253-262(2014).
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DR   EMBL; AC069213; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; C9JF17; -.
DR   SMR; C9JF17; -.
DR   jPOST; C9JF17; -.
DR   MaxQB; C9JF17; -.
DR   PeptideAtlas; C9JF17; -.
DR   PRIDE; C9JF17; -.
DR   Ensembl; ENST00000421243; ENSP00000415235; ENSG00000189058.
DR   UCSC; uc062rrr.1; human.
DR   EuPathDB; HostDB:ENSG00000189058.8; -.
DR   HGNC; HGNC:612; APOD.
DR   OpenTargets; ENSG00000189058; -.
DR   eggNOG; KOG4824; Eukaryota.
DR   eggNOG; COG3040; LUCA.
DR   GeneTree; ENSGT00510000046981; -.
DR   HOGENOM; HOG000061525; -.
DR   OMA; CIYANYG; -.
DR   PhylomeDB; C9JF17; -.
DR   ChiTaRS; APOD; human.
DR   Proteomes; UP000005640; Chromosome 3.
DR   Bgee; ENSG00000189058; Expressed in 220 organ(s), highest expression level in olfactory bulb.
DR   ExpressionAtlas; C9JF17; baseline and differential.
DR   GO; GO:0008289; F:lipid binding; IEA:InterPro.
DR   GO; GO:0007568; P:aging; IEA:InterPro.
DR   GO; GO:0006869; P:lipid transport; IEA:InterPro.
DR   Gene3D; 2.40.128.20; -; 1.
DR   InterPro; IPR026222; ApoD_vertbrte.
DR   InterPro; IPR002969; ApolipopD.
DR   InterPro; IPR012674; Calycin.
DR   InterPro; IPR022271; Lipocalin_ApoD.
DR   InterPro; IPR022272; Lipocalin_CS.
DR   InterPro; IPR000566; Lipocln_cytosolic_FA-bd_dom.
DR   Pfam; PF08212; Lipocalin_2; 1.
DR   PIRSF; PIRSF036893; Lipocalin_ApoD; 1.
DR   PRINTS; PR02058; APODVERTBRTE.
DR   PRINTS; PR01219; APOLIPOPROTD.
DR   SUPFAM; SSF50814; SSF50814; 1.
DR   PROSITE; PS00213; LIPOCALIN; 1.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Proteomics identification {ECO:0000213|MaxQB:C9JF17,
KW   ECO:0000213|PeptideAtlas:C9JF17};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     48       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        49    215       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5002996547.
FT   DOMAIN       65    210       Lipocln_cytosolic_FA-bd_dom.
FT                                {ECO:0000259|Pfam:PF08212}.
FT   NON_TER     215    215       {ECO:0000313|Ensembl:ENSP00000415235}.
SQ   SEQUENCE   215 AA;  24158 MW;  618EEA0DBC3DB0E3 CRC64;
     MFKQLSCISL PSSCDYSSRS LLQPPSPKMV MLLLLLSALA GLFGAAEGQA FHLGKCPNPP
     VQENFDVNKY LGRWYEIEKI PTTFENGRCI QANYSLMENG KIKVLNQELR ADGTVNQIEG
     EATPVNLTEP AKLEVKFSWF MPSAPYWILA TDYENYALVY SCTCIIQLFH VDFAWILARN
     PNLPPETVDS LKNILTSNNI DVKKMTVTDQ VNCPK
//