ID   C9JEV0_HUMAN            Unreviewed;       227 AA.
AC   C9JEV0;
DT   03-NOV-2009, integrated into UniProtKB/TrEMBL.
DT   03-NOV-2009, sequence version 1.
DT   16-JAN-2019, entry version 63.
DE   SubName: Full=Zinc-alpha-2-glycoprotein {ECO:0000313|Ensembl:ENSP00000396093};
GN   Name=AZGP1 {ECO:0000313|Ensembl:ENSP00000396093};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000396093, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000396093, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=12853948; DOI=10.1038/nature01782;
RA   Hillier L.W., Fulton R.S., Fulton L.A., Graves T.A., Pepin K.H.,
RA   Wagner-McPherson C., Layman D., Maas J., Jaeger S., Walker R.,
RA   Wylie K., Sekhon M., Becker M.C., O'Laughlin M.D., Schaller M.E.,
RA   Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E., Cordes M., Du H.,
RA   Sun H., Edwards J., Bradshaw-Cordum H., Ali J., Andrews S., Isak A.,
RA   Vanbrunt A., Nguyen C., Du F., Lamar B., Courtney L., Kalicki J.,
RA   Ozersky P., Bielicki L., Scott K., Holmes A., Harkins R., Harris A.,
RA   Strong C.M., Hou S., Tomlinson C., Dauphin-Kohlberg S.,
RA   Kozlowicz-Reilly A., Leonard S., Rohlfing T., Rock S.M.,
RA   Tin-Wollam A.-M., Abbott A., Minx P., Maupin R., Strowmatt C.,
RA   Latreille P., Miller N., Johnson D., Murray J., Woessner J.P.,
RA   Wendl M.C., Yang S.-P., Schultz B.R., Wallis J.W., Spieth J.,
RA   Bieri T.A., Nelson J.O., Berkowicz N., Wohldmann P.E., Cook L.L.,
RA   Hickenbotham M.T., Eldred J., Williams D., Bedell J.A., Mardis E.R.,
RA   Clifton S.W., Chissoe S.L., Marra M.A., Raymond C., Haugen E.,
RA   Gillett W., Zhou Y., James R., Phelps K., Iadanoto S., Bubb K.,
RA   Simms E., Levy R., Clendenning J., Kaul R., Kent W.J., Furey T.S.,
RA   Baertsch R.A., Brent M.R., Keibler E., Flicek P., Bork P., Suyama M.,
RA   Bailey J.A., Portnoy M.E., Torrents D., Chinwalla A.T., Gish W.R.,
RA   Eddy S.R., McPherson J.D., Olson M.V., Eichler E.E., Green E.D.,
RA   Waterston R.H., Wilson R.K.;
RT   "The DNA sequence of human chromosome 7.";
RL   Nature 424:157-164(2003).
RN   [2] {ECO:0000313|Ensembl:ENSP00000396093}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JUL-2011) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the MHC class I family.
CC       {ECO:0000256|RuleBase:RU004439}.
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DR   EMBL; AC004522; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; C9JEV0; -.
DR   SMR; C9JEV0; -.
DR   jPOST; C9JEV0; -.
DR   MaxQB; C9JEV0; -.
DR   PeptideAtlas; C9JEV0; -.
DR   PRIDE; C9JEV0; -.
DR   Ensembl; ENST00000411734; ENSP00000396093; ENSG00000160862.
DR   UCSC; uc064fxv.1; human.
DR   EuPathDB; HostDB:ENSG00000160862.12; -.
DR   HGNC; HGNC:910; AZGP1.
DR   OpenTargets; ENSG00000160862; -.
DR   eggNOG; ENOG410J9FR; Eukaryota.
DR   eggNOG; ENOG4111CJX; LUCA.
DR   GeneTree; ENSGT00940000153637; -.
DR   HOGENOM; HOG000296917; -.
DR   ChiTaRS; AZGP1; human.
DR   Proteomes; UP000005640; Chromosome 7.
DR   Bgee; ENSG00000160862; Expressed in 195 organ(s), highest expression level in minor salivary gland.
DR   ExpressionAtlas; C9JEV0; baseline and differential.
DR   Gene3D; 3.30.500.10; -; 1.
DR   InterPro; IPR011161; MHC_I-like_Ag-recog.
DR   InterPro; IPR037055; MHC_I-like_Ag-recog_sf.
DR   InterPro; IPR011162; MHC_I/II-like_Ag-recog.
DR   InterPro; IPR001039; MHC_I_a_a1/a2.
DR   Pfam; PF00129; MHC_I; 1.
DR   PRINTS; PR01638; MHCCLASSI.
DR   SUPFAM; SSF54452; SSF54452; 1.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Proteomics identification {ECO:0000213|MaxQB:C9JEV0,
KW   ECO:0000213|PeptideAtlas:C9JEV0};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     17       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        18    227       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5002996546.
FT   DOMAIN       23    198       MHC_I-like_Ag-recog.
FT                                {ECO:0000259|Pfam:PF00129}.
SQ   SEQUENCE   227 AA;  26354 MW;  ACA64485FA042F16 CRC64;
     MVPVLLSLLL LLGPAVPQEN QDGRYSLTYI YTGLSKHVED VPAFQALGSL NDLQFFRYNS
     KDRKSQPMGL WRQVEGMEDW KQDSQLQKAR EDIFMETLKD IVEYYNDSNG SHVLQGRFGC
     EIENNRSSGA FWKYYYDGKD YIEFNKEIPA WVPFDPAAQI TKQKWEAEPV YVQRAKAYLE
     EECPATLRKY LKYSKNILDR QGTHCFLLPS TEPRIKDDLR LGAQATS
//