ID   C9J9C4_HUMAN            Unreviewed;       149 AA.
AC   C9J9C4;
DT   03-NOV-2009, integrated into UniProtKB/TrEMBL.
DT   03-NOV-2009, sequence version 1.
DT   05-DEC-2018, entry version 61.
DE   SubName: Full=Semaphorin-3A {ECO:0000313|Ensembl:ENSP00000391900};
DE   Flags: Fragment;
GN   Name=SEMA3A {ECO:0000313|Ensembl:ENSP00000391900};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000391900, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000391900, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=12853948; DOI=10.1038/nature01782;
RA   Hillier L.W., Fulton R.S., Fulton L.A., Graves T.A., Pepin K.H.,
RA   Wagner-McPherson C., Layman D., Maas J., Jaeger S., Walker R.,
RA   Wylie K., Sekhon M., Becker M.C., O'Laughlin M.D., Schaller M.E.,
RA   Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E., Cordes M., Du H.,
RA   Sun H., Edwards J., Bradshaw-Cordum H., Ali J., Andrews S., Isak A.,
RA   Vanbrunt A., Nguyen C., Du F., Lamar B., Courtney L., Kalicki J.,
RA   Ozersky P., Bielicki L., Scott K., Holmes A., Harkins R., Harris A.,
RA   Strong C.M., Hou S., Tomlinson C., Dauphin-Kohlberg S.,
RA   Kozlowicz-Reilly A., Leonard S., Rohlfing T., Rock S.M.,
RA   Tin-Wollam A.-M., Abbott A., Minx P., Maupin R., Strowmatt C.,
RA   Latreille P., Miller N., Johnson D., Murray J., Woessner J.P.,
RA   Wendl M.C., Yang S.-P., Schultz B.R., Wallis J.W., Spieth J.,
RA   Bieri T.A., Nelson J.O., Berkowicz N., Wohldmann P.E., Cook L.L.,
RA   Hickenbotham M.T., Eldred J., Williams D., Bedell J.A., Mardis E.R.,
RA   Clifton S.W., Chissoe S.L., Marra M.A., Raymond C., Haugen E.,
RA   Gillett W., Zhou Y., James R., Phelps K., Iadanoto S., Bubb K.,
RA   Simms E., Levy R., Clendenning J., Kaul R., Kent W.J., Furey T.S.,
RA   Baertsch R.A., Brent M.R., Keibler E., Flicek P., Bork P., Suyama M.,
RA   Bailey J.A., Portnoy M.E., Torrents D., Chinwalla A.T., Gish W.R.,
RA   Eddy S.R., McPherson J.D., Olson M.V., Eichler E.E., Green E.D.,
RA   Waterston R.H., Wilson R.K.;
RT   "The DNA sequence of human chromosome 7.";
RL   Nature 424:157-164(2003).
RN   [2] {ECO:0000313|Ensembl:ENSP00000391900}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JUL-2011) to UniProtKB.
CC   -!- CAUTION: Lacks conserved residue(s) required for the propagation
CC       of feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00352}.
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DR   EMBL; AC004028; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC004451; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC004848; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC004907; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC006322; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC073221; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; KF458486; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; C9J9C4; -.
DR   MaxQB; C9J9C4; -.
DR   PeptideAtlas; C9J9C4; -.
DR   PRIDE; C9J9C4; -.
DR   Ensembl; ENST00000420047; ENSP00000391900; ENSG00000075213.
DR   UCSC; uc064exn.1; human.
DR   EuPathDB; HostDB:ENSG00000075213.10; -.
DR   HGNC; HGNC:10723; SEMA3A.
DR   OpenTargets; ENSG00000075213; -.
DR   eggNOG; KOG3611; Eukaryota.
DR   eggNOG; ENOG410XQZC; LUCA.
DR   GeneTree; ENSGT00940000158203; -.
DR   HOGENOM; HOG000202114; -.
DR   ChiTaRS; SEMA3A; human.
DR   Proteomes; UP000005640; Chromosome 7.
DR   Bgee; ENSG00000075213; Expressed in 128 organ(s), highest expression level in intestine.
DR   ExpressionAtlas; C9J9C4; baseline and differential.
DR   Gene3D; 2.130.10.10; -; 1.
DR   InterPro; IPR001627; Semap_dom.
DR   InterPro; IPR036352; Semap_dom_sf.
DR   InterPro; IPR027231; Semaphorin.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   PANTHER; PTHR11036; PTHR11036; 1.
DR   Pfam; PF01403; Sema; 1.
DR   SUPFAM; SSF101912; SSF101912; 1.
DR   PROSITE; PS51004; SEMA; 1.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Proteomics identification {ECO:0000213|MaxQB:C9J9C4,
KW   ECO:0000213|PeptideAtlas:C9J9C4};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     20       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        21    149       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5002997159.
FT   DOMAIN       31    149       Sema. {ECO:0000259|PROSITE:PS51004}.
FT   NON_TER     149    149       {ECO:0000313|Ensembl:ENSP00000391900}.
SQ   SEQUENCE   149 AA;  17255 MW;  4668E77F74368D0B CRC64;
     MGWLTRIVCL FWGVLLTARA NYQNGKNNVP RLKLSYKEML ESNNVITFNG LANSSSYHTF
     LLDEERSRLY VGAKDHIFSF DLVNIKDFQK IVWPVSYTRR DECKWAGKDI LKECANFIKV
     LKAYNQTHLY ACGTGAFHPI CTYIEIGHH
//