ID   C9J976_HUMAN            Unreviewed;       201 AA.
AC   C9J976;
DT   03-NOV-2009, integrated into UniProtKB/TrEMBL.
DT   03-NOV-2009, sequence version 1.
DT   05-DEC-2018, entry version 56.
DE   SubName: Full=Synaptoporin {ECO:0000313|Ensembl:ENSP00000418123};
GN   Name=SYNPR {ECO:0000313|Ensembl:ENSP00000418123};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000418123, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000418123, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16641997; DOI=10.1038/nature04728;
RA   Muzny D.M., Scherer S.E., Kaul R., Wang J., Yu J., Sudbrak R.,
RA   Buhay C.J., Chen R., Cree A., Ding Y., Dugan-Rocha S., Gill R.,
RA   Gunaratne P., Harris R.A., Hawes A.C., Hernandez J., Hodgson A.V.,
RA   Hume J., Jackson A., Khan Z.M., Kovar-Smith C., Lewis L.R.,
RA   Lozado R.J., Metzker M.L., Milosavljevic A., Miner G.R., Morgan M.B.,
RA   Nazareth L.V., Scott G., Sodergren E., Song X.Z., Steffen D., Wei S.,
RA   Wheeler D.A., Wright M.W., Worley K.C., Yuan Y., Zhang Z., Adams C.Q.,
RA   Ansari-Lari M.A., Ayele M., Brown M.J., Chen G., Chen Z.,
RA   Clendenning J., Clerc-Blankenburg K.P., Chen R., Chen Z., Davis C.,
RA   Delgado O., Dinh H.H., Dong W., Draper H., Ernst S., Fu G.,
RA   Gonzalez-Garay M.L., Garcia D.K., Gillett W., Gu J., Hao B.,
RA   Haugen E., Havlak P., He X., Hennig S., Hu S., Huang W., Jackson L.R.,
RA   Jacob L.S., Kelly S.H., Kube M., Levy R., Li Z., Liu B., Liu J.,
RA   Liu W., Lu J., Maheshwari M., Nguyen B.V., Okwuonu G.O., Palmeiri A.,
RA   Pasternak S., Perez L.M., Phelps K.A., Plopper F.J., Qiang B.,
RA   Raymond C., Rodriguez R., Saenphimmachak C., Santibanez J., Shen H.,
RA   Shen Y., Subramanian S., Tabor P.E., Verduzco D., Waldron L., Wang J.,
RA   Wang J., Wang Q., Williams G.A., Wong G.K., Yao Z., Zhang J.,
RA   Zhang X., Zhao G., Zhou J., Zhou Y., Nelson D., Lehrach H.,
RA   Reinhardt R., Naylor S.L., Yang H., Olson M., Weinstock G.,
RA   Gibbs R.A.;
RT   "The DNA sequence, annotation and analysis of human chromosome 3.";
RL   Nature 440:1194-1198(2006).
RN   [2] {ECO:0000313|Ensembl:ENSP00000418123}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JUL-2011) to UniProtKB.
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DR   EMBL; AC099056; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC099545; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC104436; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; KF457642; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; C9J976; -.
DR   PeptideAtlas; C9J976; -.
DR   PRIDE; C9J976; -.
DR   Ensembl; ENST00000465156; ENSP00000418123; ENSG00000163630.
DR   UCSC; uc062leh.1; human.
DR   EuPathDB; HostDB:ENSG00000163630.10; -.
DR   HGNC; HGNC:16507; SYNPR.
DR   OpenTargets; ENSG00000163630; -.
DR   GeneTree; ENSGT00940000153210; -.
DR   HOGENOM; HOG000252913; -.
DR   ChiTaRS; SYNPR; human.
DR   Proteomes; UP000005640; Chromosome 3.
DR   Bgee; ENSG00000163630; Expressed in 94 organ(s), highest expression level in caudate nucleus.
DR   ExpressionAtlas; C9J976; baseline and differential.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-UniRule.
DR   GO; GO:0008021; C:synaptic vesicle; IEA:InterPro.
DR   InterPro; IPR008253; Marvel.
DR   InterPro; IPR001285; Synaptophysin/porin.
DR   PANTHER; PTHR10306; PTHR10306; 2.
DR   Pfam; PF01284; MARVEL; 1.
DR   PRINTS; PR00220; SYNAPTOPHYSN.
DR   PROSITE; PS51225; MARVEL; 1.
DR   PROSITE; PS00604; SYNAPTOP; 1.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Membrane {ECO:0000256|SAAS:SAAS00507859, ECO:0000256|SAM:Phobius};
KW   Proteomics identification {ECO:0000213|PeptideAtlas:C9J976};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|SAAS:SAAS00507859,
KW   ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAAS:SAAS00507859,
KW   ECO:0000256|SAM:Phobius}.
FT   SIGNAL        1     18       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        19    201       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5002997157.
FT   TRANSMEM     81    103       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    115    134       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN        1    180       MARVEL. {ECO:0000259|PROSITE:PS51225}.
SQ   SEQUENCE   201 AA;  22298 MW;  6A54FBF3AF531A94 CRC64;
     MCMVIFAPLF AIFAFATCGG YSGGLRLSVD CVNKTESNLS IDIAFAYPFR LHQVTFEVPT
     CEGKERQKLA LIGDSSSSAE FFVTVAVFAF LYSLAATVVY IFFQNKYREN NRGPLIVFGF
     LNFILWAGNI WFVFKETGWH SSGQRYLSDP MEKHSSSYNQ GGYNQDSYGS SSGYSQQASL
     GPTSDEFGQQ PTGPTSFTNQ I
//