ID   C9J6N7_HUMAN            Unreviewed;       177 AA.
AC   C9J6N7;
DT   03-NOV-2009, integrated into UniProtKB/TrEMBL.
DT   03-NOV-2009, sequence version 1.
DT   16-JAN-2019, entry version 57.
DE   SubName: Full=Carboxypeptidase A4 {ECO:0000313|Ensembl:ENSP00000418392};
DE   Flags: Fragment;
GN   Name=CPA4 {ECO:0000313|Ensembl:ENSP00000418392};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000418392, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000418392, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=12853948; DOI=10.1038/nature01782;
RA   Hillier L.W., Fulton R.S., Fulton L.A., Graves T.A., Pepin K.H.,
RA   Wagner-McPherson C., Layman D., Maas J., Jaeger S., Walker R.,
RA   Wylie K., Sekhon M., Becker M.C., O'Laughlin M.D., Schaller M.E.,
RA   Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E., Cordes M., Du H.,
RA   Sun H., Edwards J., Bradshaw-Cordum H., Ali J., Andrews S., Isak A.,
RA   Vanbrunt A., Nguyen C., Du F., Lamar B., Courtney L., Kalicki J.,
RA   Ozersky P., Bielicki L., Scott K., Holmes A., Harkins R., Harris A.,
RA   Strong C.M., Hou S., Tomlinson C., Dauphin-Kohlberg S.,
RA   Kozlowicz-Reilly A., Leonard S., Rohlfing T., Rock S.M.,
RA   Tin-Wollam A.-M., Abbott A., Minx P., Maupin R., Strowmatt C.,
RA   Latreille P., Miller N., Johnson D., Murray J., Woessner J.P.,
RA   Wendl M.C., Yang S.-P., Schultz B.R., Wallis J.W., Spieth J.,
RA   Bieri T.A., Nelson J.O., Berkowicz N., Wohldmann P.E., Cook L.L.,
RA   Hickenbotham M.T., Eldred J., Williams D., Bedell J.A., Mardis E.R.,
RA   Clifton S.W., Chissoe S.L., Marra M.A., Raymond C., Haugen E.,
RA   Gillett W., Zhou Y., James R., Phelps K., Iadanoto S., Bubb K.,
RA   Simms E., Levy R., Clendenning J., Kaul R., Kent W.J., Furey T.S.,
RA   Baertsch R.A., Brent M.R., Keibler E., Flicek P., Bork P., Suyama M.,
RA   Bailey J.A., Portnoy M.E., Torrents D., Chinwalla A.T., Gish W.R.,
RA   Eddy S.R., McPherson J.D., Olson M.V., Eichler E.E., Green E.D.,
RA   Waterston R.H., Wilson R.K.;
RT   "The DNA sequence of human chromosome 7.";
RL   Nature 424:157-164(2003).
RN   [2] {ECO:0000313|Ensembl:ENSP00000418392}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JUL-2011) to UniProtKB.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   -----------------------------------------------------------------------
DR   EMBL; AC024085; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; C9J6N7; -.
DR   jPOST; C9J6N7; -.
DR   MaxQB; C9J6N7; -.
DR   PeptideAtlas; C9J6N7; -.
DR   PRIDE; C9J6N7; -.
DR   Ensembl; ENST00000473956; ENSP00000418392; ENSG00000128510.
DR   UCSC; uc064hzb.1; human.
DR   EuPathDB; HostDB:ENSG00000128510.10; -.
DR   HGNC; HGNC:15740; CPA4.
DR   OpenTargets; ENSG00000128510; -.
DR   GeneTree; ENSGT00940000161774; -.
DR   HOGENOM; HOG000185740; -.
DR   ChiTaRS; CPA4; human.
DR   Proteomes; UP000005640; Chromosome 7.
DR   Bgee; ENSG00000128510; Expressed in 70 organ(s), highest expression level in ectocervix.
DR   ExpressionAtlas; C9J6N7; baseline and differential.
DR   GO; GO:0004181; F:metallocarboxypeptidase activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   Gene3D; 3.30.70.340; -; 1.
DR   InterPro; IPR036990; M14A-like_propep.
DR   InterPro; IPR003146; M14A_act_pep.
DR   InterPro; IPR000834; Peptidase_M14.
DR   Pfam; PF00246; Peptidase_M14; 1.
DR   Pfam; PF02244; Propep_M14; 1.
DR   PRINTS; PR00765; CRBOXYPTASEA.
DR   PROSITE; PS00132; CARBOXYPEPT_ZN_1; 1.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Proteomics identification {ECO:0000213|EPD:C9J6N7,
KW   ECO:0000213|MaxQB:C9J6N7, ECO:0000213|PeptideAtlas:C9J6N7};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     16       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        17    177       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5002997640.
FT   DOMAIN      139    161       Peptidase_M14.
FT                                {ECO:0000259|PROSITE:PS00132}.
FT   NON_TER     177    177       {ECO:0000313|Ensembl:ENSP00000418392}.
SQ   SEQUENCE   177 AA;  20131 MW;  7A3F27785C726E91 CRC64;
     MRWILFIGAL IGSSICGQEK FFGDQVLRIN VRNGDEISKL SQLVNSNNLK LNFWKSPSSF
     NRPVDVLVPS VSLQAFKSFL RSQGLEYAVT IEDLQIYHEM DNIAADFPDL ARRVKIGHSF
     ENRPMYVLKF STGKGVRRPA VWLNAGIHSR EWISQATAIW TARKIVSDYQ RDPAITS
//