ID   C9J5G4_HUMAN            Unreviewed;       139 AA.
AC   C9J5G4;
DT   03-NOV-2009, integrated into UniProtKB/TrEMBL.
DT   05-OCT-2016, sequence version 8.
DT   16-JAN-2019, entry version 63.
DE   SubName: Full=Follistatin-related protein 1 {ECO:0000313|Ensembl:ENSP00000418505};
DE   Flags: Fragment;
GN   Name=FSTL1 {ECO:0000313|Ensembl:ENSP00000418505};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000418505, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000418505, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16641997; DOI=10.1038/nature04728;
RA   Muzny D.M., Scherer S.E., Kaul R., Wang J., Yu J., Sudbrak R.,
RA   Buhay C.J., Chen R., Cree A., Ding Y., Dugan-Rocha S., Gill R.,
RA   Gunaratne P., Harris R.A., Hawes A.C., Hernandez J., Hodgson A.V.,
RA   Hume J., Jackson A., Khan Z.M., Kovar-Smith C., Lewis L.R.,
RA   Lozado R.J., Metzker M.L., Milosavljevic A., Miner G.R., Morgan M.B.,
RA   Nazareth L.V., Scott G., Sodergren E., Song X.Z., Steffen D., Wei S.,
RA   Wheeler D.A., Wright M.W., Worley K.C., Yuan Y., Zhang Z., Adams C.Q.,
RA   Ansari-Lari M.A., Ayele M., Brown M.J., Chen G., Chen Z.,
RA   Clendenning J., Clerc-Blankenburg K.P., Chen R., Chen Z., Davis C.,
RA   Delgado O., Dinh H.H., Dong W., Draper H., Ernst S., Fu G.,
RA   Gonzalez-Garay M.L., Garcia D.K., Gillett W., Gu J., Hao B.,
RA   Haugen E., Havlak P., He X., Hennig S., Hu S., Huang W., Jackson L.R.,
RA   Jacob L.S., Kelly S.H., Kube M., Levy R., Li Z., Liu B., Liu J.,
RA   Liu W., Lu J., Maheshwari M., Nguyen B.V., Okwuonu G.O., Palmeiri A.,
RA   Pasternak S., Perez L.M., Phelps K.A., Plopper F.J., Qiang B.,
RA   Raymond C., Rodriguez R., Saenphimmachak C., Santibanez J., Shen H.,
RA   Shen Y., Subramanian S., Tabor P.E., Verduzco D., Waldron L., Wang J.,
RA   Wang J., Wang Q., Williams G.A., Wong G.K., Yao Z., Zhang J.,
RA   Zhang X., Zhao G., Zhou J., Zhou Y., Nelson D., Lehrach H.,
RA   Reinhardt R., Naylor S.L., Yang H., Olson M., Weinstock G.,
RA   Gibbs R.A.;
RT   "The DNA sequence, annotation and analysis of human chromosome 3.";
RL   Nature 440:1194-1198(2006).
RN   [2] {ECO:0000313|Ensembl:ENSP00000418505}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JUL-2011) to UniProtKB.
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DR   EMBL; AC063952; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC078982; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; C9J5G4; -.
DR   jPOST; C9J5G4; -.
DR   PeptideAtlas; C9J5G4; -.
DR   PRIDE; C9J5G4; -.
DR   Ensembl; ENST00000469005; ENSP00000418505; ENSG00000163430.
DR   UCSC; uc062mwq.1; human.
DR   EuPathDB; HostDB:ENSG00000163430.9; -.
DR   HGNC; HGNC:3972; FSTL1.
DR   OpenTargets; ENSG00000163430; -.
DR   eggNOG; ENOG410IIPU; Eukaryota.
DR   eggNOG; ENOG410ZJ7W; LUCA.
DR   GeneTree; ENSGT00940000157784; -.
DR   HOGENOM; HOG000007780; -.
DR   ChiTaRS; FSTL1; human.
DR   Proteomes; UP000005640; Chromosome 3.
DR   Bgee; ENSG00000163430; Expressed in 226 organ(s), highest expression level in connective tissue.
DR   ExpressionAtlas; C9J5G4; baseline and differential.
DR   Gene3D; 3.90.290.10; -; 1.
DR   InterPro; IPR003645; Fol_N.
DR   InterPro; IPR015369; Follistatin/Osteonectin_EGF.
DR   InterPro; IPR002350; Kazal_dom.
DR   InterPro; IPR036058; Kazal_dom_sf.
DR   InterPro; IPR036773; TB_dom_sf.
DR   Pfam; PF09289; FOLN; 1.
DR   Pfam; PF07648; Kazal_2; 1.
DR   SMART; SM00274; FOLN; 1.
DR   SMART; SM00280; KAZAL; 1.
DR   SUPFAM; SSF100895; SSF100895; 1.
DR   PROSITE; PS51465; KAZAL_2; 1.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Proteomics identification {ECO:0000213|EPD:C9J5G4,
KW   ECO:0000213|MaxQB:C9J5G4, ECO:0000213|PeptideAtlas:C9J5G4};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     20       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        21    139       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5008412908.
FT   DOMAIN       53    100       Kazal-like.
FT                                {ECO:0000259|PROSITE:PS51465}.
FT   NON_TER     139    139       {ECO:0000313|Ensembl:ENSP00000418505}.
SQ   SEQUENCE   139 AA;  15721 MW;  C944DBE0B256AB73 CRC64;
     MWKRWLALAL ALVAVAWVRA EEELRSKSKI CANVFCGAGR ECAVTEKGEP TCLCIEQCKP
     HKRPVCGSNG KTYLNHCELH RDACLTGSKI QVDYDGHCKE KKSVSPSASP VVCYQSNRDE
     LRRRIIQWLE AEIIPDGWF
//