ID   C9J4I9_HUMAN            Unreviewed;       224 AA.
AC   C9J4I9;
DT   03-NOV-2009, integrated into UniProtKB/TrEMBL.
DT   03-NOV-2009, sequence version 1.
DT   16-JAN-2019, entry version 60.
DE   SubName: Full=Peroxidasin homolog {ECO:0000313|Ensembl:ENSP00000398363};
DE   Flags: Fragment;
GN   Name=PXDN {ECO:0000313|Ensembl:ENSP00000398363};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000398363, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000398363, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15815621; DOI=10.1038/nature03466;
RA   Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H.,
RA   Minx P., Wagner-McPherson C., Layman D., Wylie K., Sekhon M.,
RA   Becker M.C., Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E.,
RA   Kremitzki C., Oddy L., Du H., Sun H., Bradshaw-Cordum H., Ali J.,
RA   Carter J., Cordes M., Harris A., Isak A., van Brunt A., Nguyen C.,
RA   Du F., Courtney L., Kalicki J., Ozersky P., Abbott S., Armstrong J.,
RA   Belter E.A., Caruso L., Cedroni M., Cotton M., Davidson T., Desai A.,
RA   Elliott G., Erb T., Fronick C., Gaige T., Haakenson W., Haglund K.,
RA   Holmes A., Harkins R., Kim K., Kruchowski S.S., Strong C.M.,
RA   Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K.,
RA   McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C.,
RA   Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N.,
RA   Swearengen-Shahid S., Snider J., Strong J.T., Thompson J., Yoakum M.,
RA   Leonard S., Pearman C., Trani L., Radionenko M., Waligorski J.E.,
RA   Wang C., Rock S.M., Tin-Wollam A.-M., Maupin R., Latreille P.,
RA   Wendl M.C., Yang S.-P., Pohl C., Wallis J.W., Spieth J., Bieri T.A.,
RA   Berkowicz N., Nelson J.O., Osborne J., Ding L., Meyer R., Sabo A.,
RA   Shotland Y., Sinha P., Wohldmann P.E., Cook L.L., Hickenbotham M.T.,
RA   Eldred J., Williams D., Jones T.A., She X., Ciccarelli F.D.,
RA   Izaurralde E., Taylor J., Schmutz J., Myers R.M., Cox D.R., Huang X.,
RA   McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C.,
RA   Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S.,
RA   Miller W., Eichler E.E., Bork P., Suyama M., Torrents D.,
RA   Waterston R.H., Wilson R.K.;
RT   "Generation and annotation of the DNA sequences of human chromosomes 2
RT   and 4.";
RL   Nature 434:724-731(2005).
RN   [2] {ECO:0000313|Ensembl:ENSP00000398363}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JUL-2011) to UniProtKB.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   -----------------------------------------------------------------------
DR   EMBL; AC009471; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; C9J4I9; -.
DR   SMR; C9J4I9; -.
DR   jPOST; C9J4I9; -.
DR   MaxQB; C9J4I9; -.
DR   PeptideAtlas; C9J4I9; -.
DR   PRIDE; C9J4I9; -.
DR   Ensembl; ENST00000425171; ENSP00000398363; ENSG00000130508.
DR   UCSC; uc061gck.1; human.
DR   EuPathDB; HostDB:ENSG00000130508.10; -.
DR   HGNC; HGNC:14966; PXDN.
DR   OpenTargets; ENSG00000130508; -.
DR   GeneTree; ENSGT00940000157666; -.
DR   HOGENOM; HOG000204974; -.
DR   ChiTaRS; PXDN; human.
DR   Proteomes; UP000005640; Chromosome 2.
DR   Bgee; ENSG00000130508; Expressed in 218 organ(s), highest expression level in lung.
DR   ExpressionAtlas; C9J4I9; baseline and differential.
DR   Gene3D; 3.80.10.10; -; 2.
DR   InterPro; IPR000483; Cys-rich_flank_reg_C.
DR   InterPro; IPR001611; Leu-rich_rpt.
DR   InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR   InterPro; IPR032675; LRR_dom_sf.
DR   Pfam; PF13855; LRR_8; 1.
DR   SMART; SM00369; LRR_TYP; 4.
DR   SMART; SM00082; LRRCT; 1.
DR   PROSITE; PS51450; LRR; 4.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Leucine-rich repeat {ECO:0000256|SAAS:SAAS00488662};
KW   Proteomics identification {ECO:0000213|EPD:C9J4I9,
KW   ECO:0000213|MaxQB:C9J4I9, ECO:0000213|PeptideAtlas:C9J4I9};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Repeat {ECO:0000256|SAAS:SAAS00597472};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     26       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        27    224       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5002997128.
FT   DOMAIN      168    220       LRRCT. {ECO:0000259|SMART:SM00082}.
FT   NON_TER     224    224       {ECO:0000313|Ensembl:ENSP00000398363}.
SQ   SEQUENCE   224 AA;  25570 MW;  B18F2B45516C5016 CRC64;
     MAKRSRGPGR RCLLALVLFC AWGTLAVVAQ KPGAGCPSRC LCFRTTVRCM HLLLEAVPAV
     APQTSILDLR FNRIREIQPG AFRRLRNLNT LLLNNNQIKR IPSGAFEDLE NLKYLYLHFN
     QIETLDPDSF QHLPKLERLF LHNNRITHLV PGTFNHLESM KRLRLDSNTL HCDCEILWLA
     DLLKTYAESG NAQAAAICEY PRRIQGRSVA TITPEELNCE RPRI
//