ID   C9J3P4_HUMAN            Unreviewed;       171 AA.
AC   C9J3P4;
DT   03-NOV-2009, integrated into UniProtKB/TrEMBL.
DT   05-OCT-2016, sequence version 8.
DT   16-JAN-2019, entry version 63.
DE   SubName: Full=Carboxypeptidase A4 {ECO:0000313|Ensembl:ENSP00000417255};
DE   Flags: Fragment;
GN   Name=CPA4 {ECO:0000313|Ensembl:ENSP00000417255};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000417255, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000417255, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=12853948; DOI=10.1038/nature01782;
RA   Hillier L.W., Fulton R.S., Fulton L.A., Graves T.A., Pepin K.H.,
RA   Wagner-McPherson C., Layman D., Maas J., Jaeger S., Walker R.,
RA   Wylie K., Sekhon M., Becker M.C., O'Laughlin M.D., Schaller M.E.,
RA   Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E., Cordes M., Du H.,
RA   Sun H., Edwards J., Bradshaw-Cordum H., Ali J., Andrews S., Isak A.,
RA   Vanbrunt A., Nguyen C., Du F., Lamar B., Courtney L., Kalicki J.,
RA   Ozersky P., Bielicki L., Scott K., Holmes A., Harkins R., Harris A.,
RA   Strong C.M., Hou S., Tomlinson C., Dauphin-Kohlberg S.,
RA   Kozlowicz-Reilly A., Leonard S., Rohlfing T., Rock S.M.,
RA   Tin-Wollam A.-M., Abbott A., Minx P., Maupin R., Strowmatt C.,
RA   Latreille P., Miller N., Johnson D., Murray J., Woessner J.P.,
RA   Wendl M.C., Yang S.-P., Schultz B.R., Wallis J.W., Spieth J.,
RA   Bieri T.A., Nelson J.O., Berkowicz N., Wohldmann P.E., Cook L.L.,
RA   Hickenbotham M.T., Eldred J., Williams D., Bedell J.A., Mardis E.R.,
RA   Clifton S.W., Chissoe S.L., Marra M.A., Raymond C., Haugen E.,
RA   Gillett W., Zhou Y., James R., Phelps K., Iadanoto S., Bubb K.,
RA   Simms E., Levy R., Clendenning J., Kaul R., Kent W.J., Furey T.S.,
RA   Baertsch R.A., Brent M.R., Keibler E., Flicek P., Bork P., Suyama M.,
RA   Bailey J.A., Portnoy M.E., Torrents D., Chinwalla A.T., Gish W.R.,
RA   Eddy S.R., McPherson J.D., Olson M.V., Eichler E.E., Green E.D.,
RA   Waterston R.H., Wilson R.K.;
RT   "The DNA sequence of human chromosome 7.";
RL   Nature 424:157-164(2003).
RN   [2] {ECO:0000313|Ensembl:ENSP00000417255}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JUL-2011) to UniProtKB.
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DR   EMBL; AC024085; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; C9J3P4; -.
DR   jPOST; C9J3P4; -.
DR   PeptideAtlas; C9J3P4; -.
DR   PRIDE; C9J3P4; -.
DR   Ensembl; ENST00000492072; ENSP00000417255; ENSG00000128510.
DR   UCSC; uc064hyz.1; human.
DR   EuPathDB; HostDB:ENSG00000128510.10; -.
DR   HGNC; HGNC:15740; CPA4.
DR   OpenTargets; ENSG00000128510; -.
DR   GeneTree; ENSGT00940000161774; -.
DR   HOGENOM; HOG000185740; -.
DR   ChiTaRS; CPA4; human.
DR   Proteomes; UP000005640; Chromosome 7.
DR   Bgee; ENSG00000128510; Expressed in 70 organ(s), highest expression level in ectocervix.
DR   ExpressionAtlas; C9J3P4; baseline and differential.
DR   GO; GO:0004181; F:metallocarboxypeptidase activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   Gene3D; 3.30.70.340; -; 1.
DR   InterPro; IPR036990; M14A-like_propep.
DR   InterPro; IPR003146; M14A_act_pep.
DR   InterPro; IPR000834; Peptidase_M14.
DR   Pfam; PF00246; Peptidase_M14; 1.
DR   Pfam; PF02244; Propep_M14; 1.
PE   1: Evidence at protein level;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Proteomics identification {ECO:0000213|EPD:C9J3P4,
KW   ECO:0000213|MaxQB:C9J3P4, ECO:0000213|PeptideAtlas:C9J3P4};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     16       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        17    171       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5008412905.
FT   DOMAIN       28    101       Propep_M14. {ECO:0000259|Pfam:PF02244}.
FT   DOMAIN      130    165       Peptidase_M14.
FT                                {ECO:0000259|Pfam:PF00246}.
FT   COILED       91    111       {ECO:0000256|SAM:Coils}.
FT   NON_TER     171    171       {ECO:0000313|Ensembl:ENSP00000417255}.
SQ   SEQUENCE   171 AA;  19605 MW;  1B8947D7CDCBF6F0 CRC64;
     MRWILFIGAL IGSSICGQEK FFGDQVLRIN VRNGDEISKL SQLVNSNNLK LNFWKSPSSF
     NRPVDVLVPS VSLQAFKSFL RSQGLEYAVT IEDLQALLDN EDDEMQHNEG QERSSNNFNY
     GAYHSLEAIY HEMDNIAADF PDLARRVKIG HSFENRPMYV LKIVSDYQRD P
//