ID   C9J1C7_HUMAN            Unreviewed;       118 AA.
AC   C9J1C7;
DT   03-NOV-2009, integrated into UniProtKB/TrEMBL.
DT   03-NOV-2009, sequence version 1.
DT   05-DEC-2018, entry version 54.
DE   SubName: Full=Mannan-binding lectin serine protease 1 {ECO:0000313|Ensembl:ENSP00000412021};
DE   Flags: Fragment;
GN   Name=MASP1 {ECO:0000313|Ensembl:ENSP00000412021};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000412021, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000412021, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16641997; DOI=10.1038/nature04728;
RA   Muzny D.M., Scherer S.E., Kaul R., Wang J., Yu J., Sudbrak R.,
RA   Buhay C.J., Chen R., Cree A., Ding Y., Dugan-Rocha S., Gill R.,
RA   Gunaratne P., Harris R.A., Hawes A.C., Hernandez J., Hodgson A.V.,
RA   Hume J., Jackson A., Khan Z.M., Kovar-Smith C., Lewis L.R.,
RA   Lozado R.J., Metzker M.L., Milosavljevic A., Miner G.R., Morgan M.B.,
RA   Nazareth L.V., Scott G., Sodergren E., Song X.Z., Steffen D., Wei S.,
RA   Wheeler D.A., Wright M.W., Worley K.C., Yuan Y., Zhang Z., Adams C.Q.,
RA   Ansari-Lari M.A., Ayele M., Brown M.J., Chen G., Chen Z.,
RA   Clendenning J., Clerc-Blankenburg K.P., Chen R., Chen Z., Davis C.,
RA   Delgado O., Dinh H.H., Dong W., Draper H., Ernst S., Fu G.,
RA   Gonzalez-Garay M.L., Garcia D.K., Gillett W., Gu J., Hao B.,
RA   Haugen E., Havlak P., He X., Hennig S., Hu S., Huang W., Jackson L.R.,
RA   Jacob L.S., Kelly S.H., Kube M., Levy R., Li Z., Liu B., Liu J.,
RA   Liu W., Lu J., Maheshwari M., Nguyen B.V., Okwuonu G.O., Palmeiri A.,
RA   Pasternak S., Perez L.M., Phelps K.A., Plopper F.J., Qiang B.,
RA   Raymond C., Rodriguez R., Saenphimmachak C., Santibanez J., Shen H.,
RA   Shen Y., Subramanian S., Tabor P.E., Verduzco D., Waldron L., Wang J.,
RA   Wang J., Wang Q., Williams G.A., Wong G.K., Yao Z., Zhang J.,
RA   Zhang X., Zhao G., Zhou J., Zhou Y., Nelson D., Lehrach H.,
RA   Reinhardt R., Naylor S.L., Yang H., Olson M., Weinstock G.,
RA   Gibbs R.A.;
RT   "The DNA sequence, annotation and analysis of human chromosome 3.";
RL   Nature 440:1194-1198(2006).
RN   [2] {ECO:0000313|Ensembl:ENSP00000412021}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JUL-2011) to UniProtKB.
CC   -!- CAUTION: Lacks conserved residue(s) required for the propagation
CC       of feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00059}.
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DR   EMBL; AC007920; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; KF457720; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; C9J1C7; -.
DR   PeptideAtlas; C9J1C7; -.
DR   PRIDE; C9J1C7; -.
DR   Ensembl; ENST00000439271; ENSP00000412021; ENSG00000127241.
DR   UCSC; uc062rgy.1; human.
DR   EuPathDB; HostDB:ENSG00000127241.16; -.
DR   HGNC; HGNC:6901; MASP1.
DR   OpenTargets; ENSG00000127241; -.
DR   eggNOG; KOG3627; Eukaryota.
DR   eggNOG; COG5640; LUCA.
DR   GeneTree; ENSGT00940000153970; -.
DR   ChiTaRS; MASP1; human.
DR   Proteomes; UP000005640; Chromosome 3.
DR   Bgee; ENSG00000127241; Expressed in 161 organ(s), highest expression level in ectocervix.
DR   ExpressionAtlas; C9J1C7; baseline and differential.
DR   CDD; cd00041; CUB; 1.
DR   Gene3D; 2.60.120.290; -; 1.
DR   InterPro; IPR000859; CUB_dom.
DR   InterPro; IPR035914; Sperma_CUB_dom_sf.
DR   Pfam; PF00431; CUB; 1.
DR   SMART; SM00042; CUB; 1.
DR   SUPFAM; SSF49854; SSF49854; 1.
DR   PROSITE; PS01180; CUB; 1.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Disulfide bond {ECO:0000256|SAAS:SAAS01008102};
KW   Proteomics identification {ECO:0000213|PeptideAtlas:C9J1C7};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     45       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        46    118       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5002997265.
FT   DOMAIN       37    118       CUB. {ECO:0000259|PROSITE:PS01180}.
FT   NON_TER     118    118       {ECO:0000313|Ensembl:ENSP00000412021}.
SQ   SEQUENCE   118 AA;  13579 MW;  C17CD8DB6BDA1B60 CRC64;
     MPANSRDTQG PQNKDKASRT PHRARAHRWL LLYYALCFSL SKASAHTVEL NNMFGQIQSP
     GYPDSYPSDS EVTWNITVPD GFRIKLYFMH FNLESSYLCE YDYVKVETED QVLATFCG
//