ID   C9J0A2_HUMAN            Unreviewed;       202 AA.
AC   C9J0A2;
DT   03-NOV-2009, integrated into UniProtKB/TrEMBL.
DT   03-NOV-2009, sequence version 1.
DT   05-DEC-2018, entry version 57.
DE   SubName: Full=Synaptoporin {ECO:0000313|Ensembl:ENSP00000418929};
GN   Name=SYNPR {ECO:0000313|Ensembl:ENSP00000418929};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000418929, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000418929, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16641997; DOI=10.1038/nature04728;
RA   Muzny D.M., Scherer S.E., Kaul R., Wang J., Yu J., Sudbrak R.,
RA   Buhay C.J., Chen R., Cree A., Ding Y., Dugan-Rocha S., Gill R.,
RA   Gunaratne P., Harris R.A., Hawes A.C., Hernandez J., Hodgson A.V.,
RA   Hume J., Jackson A., Khan Z.M., Kovar-Smith C., Lewis L.R.,
RA   Lozado R.J., Metzker M.L., Milosavljevic A., Miner G.R., Morgan M.B.,
RA   Nazareth L.V., Scott G., Sodergren E., Song X.Z., Steffen D., Wei S.,
RA   Wheeler D.A., Wright M.W., Worley K.C., Yuan Y., Zhang Z., Adams C.Q.,
RA   Ansari-Lari M.A., Ayele M., Brown M.J., Chen G., Chen Z.,
RA   Clendenning J., Clerc-Blankenburg K.P., Chen R., Chen Z., Davis C.,
RA   Delgado O., Dinh H.H., Dong W., Draper H., Ernst S., Fu G.,
RA   Gonzalez-Garay M.L., Garcia D.K., Gillett W., Gu J., Hao B.,
RA   Haugen E., Havlak P., He X., Hennig S., Hu S., Huang W., Jackson L.R.,
RA   Jacob L.S., Kelly S.H., Kube M., Levy R., Li Z., Liu B., Liu J.,
RA   Liu W., Lu J., Maheshwari M., Nguyen B.V., Okwuonu G.O., Palmeiri A.,
RA   Pasternak S., Perez L.M., Phelps K.A., Plopper F.J., Qiang B.,
RA   Raymond C., Rodriguez R., Saenphimmachak C., Santibanez J., Shen H.,
RA   Shen Y., Subramanian S., Tabor P.E., Verduzco D., Waldron L., Wang J.,
RA   Wang J., Wang Q., Williams G.A., Wong G.K., Yao Z., Zhang J.,
RA   Zhang X., Zhao G., Zhou J., Zhou Y., Nelson D., Lehrach H.,
RA   Reinhardt R., Naylor S.L., Yang H., Olson M., Weinstock G.,
RA   Gibbs R.A.;
RT   "The DNA sequence, annotation and analysis of human chromosome 3.";
RL   Nature 440:1194-1198(2006).
RN   [2] {ECO:0000313|Ensembl:ENSP00000418929}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JUL-2011) to UniProtKB.
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DR   EMBL; AC099056; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC099545; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC104436; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; KF457642; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; C9J0A2; -.
DR   PeptideAtlas; C9J0A2; -.
DR   PRIDE; C9J0A2; -.
DR   Ensembl; ENST00000479198; ENSP00000418929; ENSG00000163630.
DR   UCSC; uc062lee.1; human.
DR   EuPathDB; HostDB:ENSG00000163630.10; -.
DR   HGNC; HGNC:16507; SYNPR.
DR   OpenTargets; ENSG00000163630; -.
DR   eggNOG; ENOG410IDYC; Eukaryota.
DR   eggNOG; ENOG4111J4N; LUCA.
DR   GeneTree; ENSGT00940000153210; -.
DR   HOGENOM; HOG000252913; -.
DR   ChiTaRS; SYNPR; human.
DR   Proteomes; UP000005640; Chromosome 3.
DR   Bgee; ENSG00000163630; Expressed in 94 organ(s), highest expression level in caudate nucleus.
DR   ExpressionAtlas; C9J0A2; baseline and differential.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-UniRule.
DR   GO; GO:0008021; C:synaptic vesicle; IEA:InterPro.
DR   InterPro; IPR008253; Marvel.
DR   InterPro; IPR001285; Synaptophysin/porin.
DR   PANTHER; PTHR10306; PTHR10306; 1.
DR   Pfam; PF01284; MARVEL; 1.
DR   PRINTS; PR00220; SYNAPTOPHYSN.
DR   PROSITE; PS51225; MARVEL; 1.
DR   PROSITE; PS00604; SYNAPTOP; 1.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Membrane {ECO:0000256|SAAS:SAAS00507859, ECO:0000256|SAM:Phobius};
KW   Proteomics identification {ECO:0000213|PeptideAtlas:C9J0A2};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|SAAS:SAAS00507859,
KW   ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAAS:SAAS00507859,
KW   ECO:0000256|SAM:Phobius}.
FT   SIGNAL        1     18       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        19    202       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5002997079.
FT   TRANSMEM     81    103       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    115    136       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN        1    197       MARVEL. {ECO:0000259|PROSITE:PS51225}.
SQ   SEQUENCE   202 AA;  22137 MW;  57CA3F60F678C668 CRC64;
     MCMVIFAPLF AIFAFATCGG YSGGLRLSVD CVNKTESNLS IDIAFAYPFR LHQVTFEVPT
     CEGKERQKLA LIGDSSSSAE FFVTVAVFAF LYSLAATVVY IFFQNKYREN NRGPLIDFIV
     TVVFSFLWLV GSSAWAKGLS DVKVATDPKE VLLLMSACKQ PSNKCMAIHS PVMSSLNTSV
     LSEIQSAKAL KKRERVATLT GL
//