ID   C9IZN0_HUMAN            Unreviewed;       348 AA.
AC   C9IZN0;
DT   03-NOV-2009, integrated into UniProtKB/TrEMBL.
DT   03-NOV-2009, sequence version 1.
DT   05-DEC-2018, entry version 51.
DE   SubName: Full=Interleukin-17 receptor B {ECO:0000313|Ensembl:ENSP00000418638};
DE   Flags: Fragment;
GN   Name=IL17RB {ECO:0000313|Ensembl:ENSP00000418638};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000418638, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000418638, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16641997; DOI=10.1038/nature04728;
RA   Muzny D.M., Scherer S.E., Kaul R., Wang J., Yu J., Sudbrak R.,
RA   Buhay C.J., Chen R., Cree A., Ding Y., Dugan-Rocha S., Gill R.,
RA   Gunaratne P., Harris R.A., Hawes A.C., Hernandez J., Hodgson A.V.,
RA   Hume J., Jackson A., Khan Z.M., Kovar-Smith C., Lewis L.R.,
RA   Lozado R.J., Metzker M.L., Milosavljevic A., Miner G.R., Morgan M.B.,
RA   Nazareth L.V., Scott G., Sodergren E., Song X.Z., Steffen D., Wei S.,
RA   Wheeler D.A., Wright M.W., Worley K.C., Yuan Y., Zhang Z., Adams C.Q.,
RA   Ansari-Lari M.A., Ayele M., Brown M.J., Chen G., Chen Z.,
RA   Clendenning J., Clerc-Blankenburg K.P., Chen R., Chen Z., Davis C.,
RA   Delgado O., Dinh H.H., Dong W., Draper H., Ernst S., Fu G.,
RA   Gonzalez-Garay M.L., Garcia D.K., Gillett W., Gu J., Hao B.,
RA   Haugen E., Havlak P., He X., Hennig S., Hu S., Huang W., Jackson L.R.,
RA   Jacob L.S., Kelly S.H., Kube M., Levy R., Li Z., Liu B., Liu J.,
RA   Liu W., Lu J., Maheshwari M., Nguyen B.V., Okwuonu G.O., Palmeiri A.,
RA   Pasternak S., Perez L.M., Phelps K.A., Plopper F.J., Qiang B.,
RA   Raymond C., Rodriguez R., Saenphimmachak C., Santibanez J., Shen H.,
RA   Shen Y., Subramanian S., Tabor P.E., Verduzco D., Waldron L., Wang J.,
RA   Wang J., Wang Q., Williams G.A., Wong G.K., Yao Z., Zhang J.,
RA   Zhang X., Zhao G., Zhou J., Zhou Y., Nelson D., Lehrach H.,
RA   Reinhardt R., Naylor S.L., Yang H., Olson M., Weinstock G.,
RA   Gibbs R.A.;
RT   "The DNA sequence, annotation and analysis of human chromosome 3.";
RL   Nature 440:1194-1198(2006).
RN   [2] {ECO:0000313|Ensembl:ENSP00000418638}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JUL-2011) to UniProtKB.
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DR   EMBL; AC012467; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; C9IZN0; -.
DR   MaxQB; C9IZN0; -.
DR   PeptideAtlas; C9IZN0; -.
DR   PRIDE; C9IZN0; -.
DR   Ensembl; ENST00000494338; ENSP00000418638; ENSG00000056736.
DR   UCSC; uc062ksx.1; human.
DR   EuPathDB; HostDB:ENSG00000056736.9; -.
DR   HGNC; HGNC:18015; IL17RB.
DR   OpenTargets; ENSG00000056736; -.
DR   eggNOG; ENOG410IK7X; Eukaryota.
DR   eggNOG; ENOG410YA4Q; LUCA.
DR   GeneTree; ENSGT00940000161145; -.
DR   HOGENOM; HOG000112985; -.
DR   Proteomes; UP000005640; Chromosome 3.
DR   Bgee; ENSG00000056736; Expressed in 169 organ(s), highest expression level in adult mammalian kidney.
DR   ExpressionAtlas; C9IZN0; baseline and differential.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0030368; F:interleukin-17 receptor activity; IEA:InterPro.
DR   Gene3D; 2.60.40.2160; -; 1.
DR   InterPro; IPR039465; IL-17_rcpt-like.
DR   InterPro; IPR032356; IL17R_fnIII_D1.
DR   InterPro; IPR038683; IL17RA/B_FnIII-like_1_sf.
DR   InterPro; IPR013568; SEFIR_dom.
DR   PANTHER; PTHR15583; PTHR15583; 1.
DR   Pfam; PF16556; IL17R_fnIII_D1; 1.
DR   Pfam; PF08357; SEFIR; 1.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Proteomics identification {ECO:0000213|PeptideAtlas:C9IZN0};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   SIGNAL        1     17       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        18    348       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5002997071.
FT   TRANSMEM    274    297       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       32    162       IL17R_fnIII_D1.
FT                                {ECO:0000259|Pfam:PF16556}.
FT   DOMAIN      317    348       SEFIR. {ECO:0000259|Pfam:PF08357}.
FT   NON_TER     348    348       {ECO:0000313|Ensembl:ENSP00000418638}.
SQ   SEQUENCE   348 AA;  38595 MW;  6474E3F5FDAB0247 CRC64;
     MSLVLLSLAA LCRSAVPREP TVQCGSETGP SPEWMLQHDL IPGDLRDLRV EPVTTSVATG
     DYSILMNVSW VLRADASIRL LKATKICVTG KSNFQSYSCV RCNYTEAFQT QTRPSGGKWT
     FSYIGFPVEL NTVYFIGAHN IPNANMNEDG PSMSVNFTSP GSLWDPNITA CKKNEETVEV
     NFTTTPLGNR YMALIQHSTI IGFSQVFEPH QKKQTRASVV IPVTGDSEGA TVQLTPYFPT
     CGSDCIRHKG TVVLCPQTGV PFPLDNNKSK PGGWLPLLLL SLLVATWVLV AGIYLMWRHE
     RIKKTSFSTT TLLPPIKVLV VYPSEICFHH TICYFTEFLQ NHCRSEVI
//