ID   C4N360_HUMAN            Unreviewed;       444 AA.
AC   C4N360;
DT   07-JUL-2009, integrated into UniProtKB/TrEMBL.
DT   07-JUL-2009, sequence version 1.
DT   18-JUL-2018, entry version 58.
DE   SubName: Full=KIR3DL1/S1 {ECO:0000313|EMBL:ACJ37429.1};
DE   SubName: Full=Killer cell immunoglobulin-like receptor 3DL1 {ECO:0000313|Ensembl:ENSP00000481282};
GN   Name=KIR3DL1 {ECO:0000313|EMBL:ACJ37429.1,
GN   ECO:0000313|Ensembl:ENSP00000481282};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|EMBL:ACJ37429.1};
RN   [1] {ECO:0000313|Ensembl:ENSP00000481282, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15057824; DOI=10.1038/nature02399;
RA   Grimwood J., Gordon L.A., Olsen A.S., Terry A., Schmutz J.,
RA   Lamerdin J.E., Hellsten U., Goodstein D., Couronne O., Tran-Gyamfi M.,
RA   Aerts A., Altherr M., Ashworth L., Bajorek E., Black S., Branscomb E.,
RA   Caenepeel S., Carrano A.V., Caoile C., Chan Y.M., Christensen M.,
RA   Cleland C.A., Copeland A., Dalin E., Dehal P., Denys M., Detter J.C.,
RA   Escobar J., Flowers D., Fotopulos D., Garcia C., Georgescu A.M.,
RA   Glavina T., Gomez M., Gonzales E., Groza M., Hammon N., Hawkins T.,
RA   Haydu L., Ho I., Huang W., Israni S., Jett J., Kadner K., Kimball H.,
RA   Kobayashi A., Larionov V., Leem S.-H., Lopez F., Lou Y., Lowry S.,
RA   Malfatti S., Martinez D., McCready P.M., Medina C., Morgan J.,
RA   Nelson K., Nolan M., Ovcharenko I., Pitluck S., Pollard M.,
RA   Popkie A.P., Predki P., Quan G., Ramirez L., Rash S., Retterer J.,
RA   Rodriguez A., Rogers S., Salamov A., Salazar A., She X., Smith D.,
RA   Slezak T., Solovyev V., Thayer N., Tice H., Tsai M., Ustaszewska A.,
RA   Vo N., Wagner M., Wheeler J., Wu K., Xie G., Yang J., Dubchak I.,
RA   Furey T.S., DeJong P., Dickson M., Gordon D., Eichler E.E.,
RA   Pennacchio L.A., Richardson P., Stubbs L., Rokhsar D.S., Myers R.M.,
RA   Rubin E.M., Lucas S.M.;
RT   "The DNA sequence and biology of human chromosome 19.";
RL   Nature 428:529-535(2004).
RN   [2] {ECO:0000313|EMBL:AAX89514.1}
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=17694054; DOI=10.1038/ng2111;
RA   Norman P.J., Abi-Rached L., Gendzekhadze K., Korbel D., Gleimer M.,
RA   Rowley D., Bruno D., Carrington C.V., Chandanayingyong D., Chang Y.H.,
RA   Crespi C., Saruhan-Direskeneli G., Fraser P.A., Hameed K.,
RA   Kamkamidze G., Koram K.A., Layrisse Z., Matamoros N., Mila J.,
RA   Park M.H., Pitchappan R.M., Ramdath D.D., Shiau M.Y., Stephens H.A.,
RA   Struik S., Verity D.H., Vaughan R.W., Tyan D., Davis R.W., Riley E.M.,
RA   Ronaghi M., Parham P.;
RT   "Unusual selection on the KIR3DL1/S1 natural killer cell receptor in
RT   Africans.";
RL   Nat. Genet. 39:1092-1099(2007).
RN   [3] {ECO:0000313|EMBL:ACJ37429.1}
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=19411600; DOI=10.1101/gr.085738.108;
RA   Norman P.J., Abi-Rached L., Gendzekhadze K., Hammond J.A.,
RA   Moesta A.K., Sharma D., Graef T., McQueen K.L., Guethlein L.A.,
RA   Carrington C.V.F., Chandanayingyong D., Chang Y.-H., Crespi C.,
RA   Saruhan-Direskeneli G., Hameed K., Kamkamidze G., Koram K.A.,
RA   Layrisse Z., Matamoros N., Mila J., Park M.H., Pitshappan R.M.,
RA   Ramdath D.D., Shiau M.-Y., Stephens H.A.F., Struik S., Tyan D.,
RA   Verity D.H., Vaughan R.W., Davis R.W., Fraser P.A., Riley E.M.,
RA   Ronaghi M., Parham P.;
RT   "Meiotic recombination generates rich diversity in NK cell receptor
RT   genes, alleles, and haplotypes.";
RL   Genome Res. 19:757-769(2009).
RN   [4] {ECO:0000313|Ensembl:ENSP00000481282}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JUN-2015) to UniProtKB.
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DR   EMBL; GU182350; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; GU182353; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AY760043; AAX89514.1; -; Genomic_DNA.
DR   EMBL; FJ158655; ACJ37429.1; -; Genomic_DNA.
DR   UniGene; Hs.645228; -.
DR   PeptideAtlas; C4N360; -.
DR   PRIDE; C4N360; -.
DR   Ensembl; ENST00000610345; ENSP00000481653; ENSG00000277175.
DR   Ensembl; ENST00000615523; ENSP00000481282; ENSG00000278427.
DR   UCSC; uc061euf.1; human.
DR   HGNC; HGNC:6338; KIR3DL1.
DR   eggNOG; ENOG410JAMM; Eukaryota.
DR   eggNOG; ENOG410ZT7K; LUCA.
DR   Proteomes; UP000005640; Chromosome 19.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.40.10; -; 3.
DR   InterPro; IPR036179; Ig-like_dom_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR003599; Ig_sub.
DR   InterPro; IPR013151; Immunoglobulin.
DR   Pfam; PF00047; ig; 3.
DR   SMART; SM00409; IG; 3.
DR   SUPFAM; SSF48726; SSF48726; 3.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Immunoglobulin domain {ECO:0000256|SAAS:SAAS00442402};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Proteomics identification {ECO:0000213|MaxQB:C4N360,
KW   ECO:0000213|PeptideAtlas:C4N360};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   SIGNAL        1     18       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        19    444       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5014086363.
FT   TRANSMEM    339    363       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       34    118       IG. {ECO:0000259|SMART:SM00409}.
FT   DOMAIN      129    209       IG. {ECO:0000259|SMART:SM00409}.
FT   DOMAIN      229    316       IG. {ECO:0000259|SMART:SM00409}.
SQ   SEQUENCE   444 AA;  49112 MW;  B3604505E05F9934 CRC64;
     MLLMVVSMAC VGFFLVQRAG PHVGGQDKPF LSAWPSAVVP RGGHVTLRCH YRHRFNNFML
     YKEDRIHVPI FHGRLFQESF NMSPVTTAHA GNYTCRGSHP HSPTGWSAPS NPVVIMVTGN
     HRKPSLLAHP GPLVKSGERV ILQCWSDIMF EHFFLHKEGI SKDPSRLVGQ IHDGVSKANF
     SIGPMMLALA GTYRCYGSVT HTPYQLSAPS DPLDIVVTGP YEKPSLSAQP GPKVQAGESV
     TLSCSSRSSY DMYHLSREGG AHERRLPAVR KVNRTFKADF PLGPATHGGT YRCFGSFRHS
     PYEWSDPSDP LLVSVTGNPS SSWPSPTEPS SKSGNPRHLH ILIGTSVVII LFILLLFFLL
     HLWCSNKKNA AVMDQEPAGN RTANSEDSDE QDPEEVTYAQ LDHCVFTQRK ITRPSQRPKT
     PPTDTILYTE LPNAKPRSKV VSCP
//