ID   B7Z6U3_HUMAN            Unreviewed;       162 AA.
AC   B7Z6U3;
DT   03-MAR-2009, integrated into UniProtKB/TrEMBL.
DT   03-MAR-2009, sequence version 1.
DT   16-JAN-2019, entry version 74.
DE   SubName: Full=Lysosomal acid phosphatase {ECO:0000313|Ensembl:ENSP00000434205};
DE   SubName: Full=cDNA FLJ51107, highly similar to Lysosomal acid phosphatase {ECO:0000313|EMBL:BAH13379.1};
GN   Name=ACP2 {ECO:0000313|Ensembl:ENSP00000434205};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|EMBL:BAH13379.1};
RN   [1] {ECO:0000313|Ensembl:ENSP00000434205, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16554811; DOI=10.1038/nature04632;
RA   Taylor T.D., Noguchi H., Totoki Y., Toyoda A., Kuroki Y., Dewar K.,
RA   Lloyd C., Itoh T., Takeda T., Kim D.W., She X., Barlow K.F., Bloom T.,
RA   Bruford E., Chang J.L., Cuomo C.A., Eichler E., FitzGerald M.G.,
RA   Jaffe D.B., LaButti K., Nicol R., Park H.S., Seaman C., Sougnez C.,
RA   Yang X., Zimmer A.R., Zody M.C., Birren B.W., Nusbaum C., Fujiyama A.,
RA   Hattori M., Rogers J., Lander E.S., Sakaki Y.;
RT   "Human chromosome 11 DNA sequence and analysis including novel gene
RT   identification.";
RL   Nature 440:497-500(2006).
RN   [2] {ECO:0000313|EMBL:BAH13379.1}
RP   NUCLEOTIDE SEQUENCE.
RC   TISSUE=Small intestine {ECO:0000313|EMBL:BAH13379.1};
RA   Wakamatsu A., Yamamoto J., Kimura K., Ishii S., Watanabe K.,
RA   Sugiyama A., Murakawa K., Kaida T., Tsuchiya K., Fukuzumi Y.,
RA   Kumagai A., Oishi Y., Yamamoto S., Ono Y., Komori Y., Yamazaki M.,
RA   Kisu Y., Nishikawa T., Sugano S., Nomura N., Isogai T.;
RT   "NEDO human cDNA sequencing project focused on splicing variants.";
RL   Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases.
RN   [3] {ECO:0000313|Ensembl:ENSP00000434205}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (FEB-2012) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the histidine acid phosphatase family.
CC       {ECO:0000256|SAAS:SAAS00793915}.
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DR   EMBL; AC018410; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AK300931; BAH13379.1; -; mRNA.
DR   UniGene; Hs.532492; -.
DR   jPOST; B7Z6U3; -.
DR   MaxQB; B7Z6U3; -.
DR   PRIDE; B7Z6U3; -.
DR   Ensembl; ENST00000530453; ENSP00000434205; ENSG00000134575.
DR   UCSC; uc058bce.1; human.
DR   EuPathDB; HostDB:ENSG00000134575.9; -.
DR   HGNC; HGNC:123; ACP2.
DR   OpenTargets; ENSG00000134575; -.
DR   eggNOG; KOG3720; Eukaryota.
DR   eggNOG; ENOG410ZVBQ; LUCA.
DR   GeneTree; ENSGT00940000158446; -.
DR   HOGENOM; HOG000198917; -.
DR   HOVERGEN; HBG106194; -.
DR   ChiTaRS; ACP2; human.
DR   Proteomes; UP000005640; Chromosome 11.
DR   Bgee; ENSG00000134575; Expressed in 218 organ(s), highest expression level in right lobe of liver.
DR   ExpressionAtlas; B7Z6U3; baseline and differential.
DR   CDD; cd07061; HP_HAP_like; 1.
DR   Gene3D; 3.40.50.1240; -; 1.
DR   InterPro; IPR033379; Acid_Pase_AS.
DR   InterPro; IPR000560; His_Pase_clade-2.
DR   InterPro; IPR029033; His_PPase_superfam.
DR   Pfam; PF00328; His_Phos_2; 1.
DR   SUPFAM; SSF53254; SSF53254; 1.
DR   PROSITE; PS00616; HIS_ACID_PHOSPHAT_1; 1.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Proteomics identification {ECO:0000213|EPD:B7Z6U3,
KW   ECO:0000213|MaxQB:B7Z6U3, ECO:0000213|PeptideAtlas:B7Z6U3};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     30       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        31    162       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5014085667.
SQ   SEQUENCE   162 AA;  18672 MW;  B845D6E0C1DB2243 CRC64;
     MAGKRSGWSR AALLQLLLGV NLVVMPPTRA RSLRFVTLLY RHGDRSPVKT YPKDPYQEEE
     WPQGFGQLTK EGMLQHWELG QALRQRYHGF LNTSYHRQEV YVRSTDFDRT LMSAEANLAG
     LFPPNGMQRF NPNISWQPIP VHTVPITEDR QAQVTRTVEH SA
//