ID   B5MCZ9_HUMAN            Unreviewed;       284 AA.
AC   B5MCZ9;
DT   14-OCT-2008, integrated into UniProtKB/TrEMBL.
DT   14-OCT-2008, sequence version 1.
DT   16-JAN-2019, entry version 55.
DE   SubName: Full=Glutaminyl-peptide cyclotransferase {ECO:0000313|Ensembl:ENSP00000385391};
DE   Flags: Fragment;
GN   Name=QPCT {ECO:0000313|Ensembl:ENSP00000385391};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000385391, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000385391, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15815621; DOI=10.1038/nature03466;
RA   Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H.,
RA   Minx P., Wagner-McPherson C., Layman D., Wylie K., Sekhon M.,
RA   Becker M.C., Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E.,
RA   Kremitzki C., Oddy L., Du H., Sun H., Bradshaw-Cordum H., Ali J.,
RA   Carter J., Cordes M., Harris A., Isak A., van Brunt A., Nguyen C.,
RA   Du F., Courtney L., Kalicki J., Ozersky P., Abbott S., Armstrong J.,
RA   Belter E.A., Caruso L., Cedroni M., Cotton M., Davidson T., Desai A.,
RA   Elliott G., Erb T., Fronick C., Gaige T., Haakenson W., Haglund K.,
RA   Holmes A., Harkins R., Kim K., Kruchowski S.S., Strong C.M.,
RA   Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K.,
RA   McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C.,
RA   Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N.,
RA   Swearengen-Shahid S., Snider J., Strong J.T., Thompson J., Yoakum M.,
RA   Leonard S., Pearman C., Trani L., Radionenko M., Waligorski J.E.,
RA   Wang C., Rock S.M., Tin-Wollam A.-M., Maupin R., Latreille P.,
RA   Wendl M.C., Yang S.-P., Pohl C., Wallis J.W., Spieth J., Bieri T.A.,
RA   Berkowicz N., Nelson J.O., Osborne J., Ding L., Meyer R., Sabo A.,
RA   Shotland Y., Sinha P., Wohldmann P.E., Cook L.L., Hickenbotham M.T.,
RA   Eldred J., Williams D., Jones T.A., She X., Ciccarelli F.D.,
RA   Izaurralde E., Taylor J., Schmutz J., Myers R.M., Cox D.R., Huang X.,
RA   McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C.,
RA   Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S.,
RA   Miller W., Eichler E.E., Bork P., Suyama M., Torrents D.,
RA   Waterston R.H., Wilson R.K.;
RT   "Generation and annotation of the DNA sequences of human chromosomes 2
RT   and 4.";
RL   Nature 434:724-731(2005).
RN   [2] {ECO:0000313|Ensembl:ENSP00000385391}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JUL-2011) to UniProtKB.
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DR   EMBL; AC007391; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; B5MCZ9; -.
DR   jPOST; B5MCZ9; -.
DR   PeptideAtlas; B5MCZ9; -.
DR   PRIDE; B5MCZ9; -.
DR   Ensembl; ENST00000404976; ENSP00000385391; ENSG00000115828.
DR   UCSC; uc061ieo.1; human.
DR   EuPathDB; HostDB:ENSG00000115828.15; -.
DR   HGNC; HGNC:9753; QPCT.
DR   OpenTargets; ENSG00000115828; -.
DR   GeneTree; ENSGT00390000003107; -.
DR   HOGENOM; HOG000189291; -.
DR   HOVERGEN; HBG009812; -.
DR   ChiTaRS; QPCT; human.
DR   Proteomes; UP000005640; Chromosome 2.
DR   Bgee; ENSG00000115828; Expressed in 204 organ(s), highest expression level in bone marrow.
DR   ExpressionAtlas; B5MCZ9; baseline and differential.
DR   GO; GO:0016603; F:glutaminyl-peptide cyclotransferase activity; IEA:InterPro.
DR   CDD; cd03880; M28_QC_like; 1.
DR   InterPro; IPR037457; M28_QC_like.
DR   InterPro; IPR007484; Peptidase_M28.
DR   InterPro; IPR040234; QC/QCL.
DR   PANTHER; PTHR12283; PTHR12283; 1.
DR   Pfam; PF04389; Peptidase_M28; 1.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Proteomics identification {ECO:0000213|MaxQB:B5MCZ9,
KW   ECO:0000213|PeptideAtlas:B5MCZ9};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     28       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        29    284       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5002836725.
FT   DOMAIN       73    283       Peptidase_M28.
FT                                {ECO:0000259|Pfam:PF04389}.
FT   NON_TER     284    284       {ECO:0000313|Ensembl:ENSP00000385391}.
SQ   SEQUENCE   284 AA;  32108 MW;  D9BA6D57F969FF79 CRC64;
     MAGGRHRRVV GTLHLLLLVA ALPWASRGVS PSASAWPEEK HIMQRIQRLQ ADWVLEIDTF
     LSQTPYGYRS FSNIISTLNP TAKRHLVLAC HYDSKYFSHW NNRVFVGATD SAVPCAMMLE
     LARALDKKLL SLKTVSDSKP DLSLQLIFFD GEEAFLHWSP QDSLYGSRHL AAKMASTPHP
     PGARGTSQLH GMDLLVLLDL IGAPNPTFPN FFPNSARWFE RLQAIEHELH ELGLLKDHSL
     EGRYFQNYSY GGVIQDDHIP FLRRGVPVLH LIPSPFPEVW HTMD
//