ID   B5MCX6_HUMAN            Unreviewed;       309 AA.
AC   B5MCX6;
DT   14-OCT-2008, integrated into UniProtKB/TrEMBL.
DT   14-OCT-2008, sequence version 1.
DT   16-JAN-2019, entry version 65.
DE   SubName: Full=V-set and transmembrane domain-containing protein 2A {ECO:0000313|Ensembl:ENSP00000384701};
GN   Name=VSTM2A {ECO:0000313|Ensembl:ENSP00000384701};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000384701, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000384701, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=12853948; DOI=10.1038/nature01782;
RA   Hillier L.W., Fulton R.S., Fulton L.A., Graves T.A., Pepin K.H.,
RA   Wagner-McPherson C., Layman D., Maas J., Jaeger S., Walker R.,
RA   Wylie K., Sekhon M., Becker M.C., O'Laughlin M.D., Schaller M.E.,
RA   Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E., Cordes M., Du H.,
RA   Sun H., Edwards J., Bradshaw-Cordum H., Ali J., Andrews S., Isak A.,
RA   Vanbrunt A., Nguyen C., Du F., Lamar B., Courtney L., Kalicki J.,
RA   Ozersky P., Bielicki L., Scott K., Holmes A., Harkins R., Harris A.,
RA   Strong C.M., Hou S., Tomlinson C., Dauphin-Kohlberg S.,
RA   Kozlowicz-Reilly A., Leonard S., Rohlfing T., Rock S.M.,
RA   Tin-Wollam A.-M., Abbott A., Minx P., Maupin R., Strowmatt C.,
RA   Latreille P., Miller N., Johnson D., Murray J., Woessner J.P.,
RA   Wendl M.C., Yang S.-P., Schultz B.R., Wallis J.W., Spieth J.,
RA   Bieri T.A., Nelson J.O., Berkowicz N., Wohldmann P.E., Cook L.L.,
RA   Hickenbotham M.T., Eldred J., Williams D., Bedell J.A., Mardis E.R.,
RA   Clifton S.W., Chissoe S.L., Marra M.A., Raymond C., Haugen E.,
RA   Gillett W., Zhou Y., James R., Phelps K., Iadanoto S., Bubb K.,
RA   Simms E., Levy R., Clendenning J., Kaul R., Kent W.J., Furey T.S.,
RA   Baertsch R.A., Brent M.R., Keibler E., Flicek P., Bork P., Suyama M.,
RA   Bailey J.A., Portnoy M.E., Torrents D., Chinwalla A.T., Gish W.R.,
RA   Eddy S.R., McPherson J.D., Olson M.V., Eichler E.E., Green E.D.,
RA   Waterston R.H., Wilson R.K.;
RT   "The DNA sequence of human chromosome 7.";
RL   Nature 424:157-164(2003).
RN   [2] {ECO:0000313|Ensembl:ENSP00000384701}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JUL-2011) to UniProtKB.
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DR   EMBL; AC011228; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC069313; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; B5MCX6; -.
DR   PRIDE; B5MCX6; -.
DR   Ensembl; ENST00000404951; ENSP00000384701; ENSG00000170419.
DR   UCSC; uc064drz.1; human.
DR   EuPathDB; HostDB:ENSG00000170419.10; -.
DR   HGNC; HGNC:28499; VSTM2A.
DR   OpenTargets; ENSG00000170419; -.
DR   GeneTree; ENSGT00940000160556; -.
DR   HOGENOM; HOG000253955; -.
DR   HOVERGEN; HBG052093; -.
DR   PhylomeDB; B5MCX6; -.
DR   Proteomes; UP000005640; Chromosome 7.
DR   Bgee; ENSG00000170419; Expressed in 92 organ(s), highest expression level in primary visual cortex.
DR   ExpressionAtlas; B5MCX6; baseline and differential.
DR   Gene3D; 2.60.40.10; -; 1.
DR   InterPro; IPR007110; Ig-like_dom.
DR   InterPro; IPR036179; Ig-like_dom_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR003599; Ig_sub.
DR   InterPro; IPR013106; Ig_V-set.
DR   Pfam; PF07686; V-set; 1.
DR   SMART; SM00409; IG; 1.
DR   SUPFAM; SSF48726; SSF48726; 1.
DR   PROSITE; PS50835; IG_LIKE; 1.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Proteomics identification {ECO:0000213|PeptideAtlas:B5MCX6};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     24       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        25    309       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5002834832.
FT   DOMAIN       27    143       Ig-like. {ECO:0000259|PROSITE:PS50835}.
SQ   SEQUENCE   309 AA;  33856 MW;  5D4DBC2036E1EF6E CRC64;
     MMGIFLVYVG FVFFSVLYVQ QGLSSQAKFT EFPRNVTATE GQNVEMSCAF QSGSASVYLE
     IQWWFLRGPE DLDPGAEGAG AQVELLPDRD PDSDGTKIST VKVQGNDISH KLQISKVRKK
     DEGLYECRVT DANYGELQEH KAQAYLKVNA NSHARRMQAF EASPMWLQDM KPRKNVSAAI
     PSSIHGSANQ RTHSTSSPQV VAKIPKQSPQ SVSPILPEVK HLHRPPLLVL PFFSLSSLFS
     TDPLPTFPTS HRTVKRLPAP LPQPGHGSTP GVQSCVLAPP AKSKSPVKST ERTAKLTLNS
     KHHPAPTVL
//