ID   B5MCE1_HUMAN            Unreviewed;       331 AA.
AC   B5MCE1;
DT   14-OCT-2008, integrated into UniProtKB/TrEMBL.
DT   14-OCT-2008, sequence version 1.
DT   16-JAN-2019, entry version 68.
DE   SubName: Full=Pregnancy-specific beta-1-glycoprotein 6 {ECO:0000313|Ensembl:ENSP00000385736};
GN   Name=PSG6 {ECO:0000313|Ensembl:ENSP00000385736};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000385736, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000385736, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15057824; DOI=10.1038/nature02399;
RA   Grimwood J., Gordon L.A., Olsen A.S., Terry A., Schmutz J.,
RA   Lamerdin J.E., Hellsten U., Goodstein D., Couronne O., Tran-Gyamfi M.,
RA   Aerts A., Altherr M., Ashworth L., Bajorek E., Black S., Branscomb E.,
RA   Caenepeel S., Carrano A.V., Caoile C., Chan Y.M., Christensen M.,
RA   Cleland C.A., Copeland A., Dalin E., Dehal P., Denys M., Detter J.C.,
RA   Escobar J., Flowers D., Fotopulos D., Garcia C., Georgescu A.M.,
RA   Glavina T., Gomez M., Gonzales E., Groza M., Hammon N., Hawkins T.,
RA   Haydu L., Ho I., Huang W., Israni S., Jett J., Kadner K., Kimball H.,
RA   Kobayashi A., Larionov V., Leem S.-H., Lopez F., Lou Y., Lowry S.,
RA   Malfatti S., Martinez D., McCready P.M., Medina C., Morgan J.,
RA   Nelson K., Nolan M., Ovcharenko I., Pitluck S., Pollard M.,
RA   Popkie A.P., Predki P., Quan G., Ramirez L., Rash S., Retterer J.,
RA   Rodriguez A., Rogers S., Salamov A., Salazar A., She X., Smith D.,
RA   Slezak T., Solovyev V., Thayer N., Tice H., Tsai M., Ustaszewska A.,
RA   Vo N., Wagner M., Wheeler J., Wu K., Xie G., Yang J., Dubchak I.,
RA   Furey T.S., DeJong P., Dickson M., Gordon D., Eichler E.E.,
RA   Pennacchio L.A., Richardson P., Stubbs L., Rokhsar D.S., Myers R.M.,
RA   Rubin E.M., Lucas S.M.;
RT   "The DNA sequence and biology of human chromosome 19.";
RL   Nature 428:529-535(2004).
RN   [2] {ECO:0000313|Ensembl:ENSP00000385736}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JUL-2011) to UniProtKB.
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DR   EMBL; AC005260; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; B5MCE1; -.
DR   jPOST; B5MCE1; -.
DR   PeptideAtlas; B5MCE1; -.
DR   PRIDE; B5MCE1; -.
DR   Ensembl; ENST00000402603; ENSP00000385736; ENSG00000170848.
DR   UCSC; uc060zix.1; human.
DR   EuPathDB; HostDB:ENSG00000170848.15; -.
DR   HGNC; HGNC:9523; PSG6.
DR   OpenTargets; ENSG00000170848; -.
DR   GeneTree; ENSGT00940000153087; -.
DR   HOGENOM; HOG000233417; -.
DR   HOVERGEN; HBG007922; -.
DR   ChiTaRS; PSG6; human.
DR   Proteomes; UP000005640; Chromosome 19.
DR   Bgee; ENSG00000170848; Expressed in 36 organ(s), highest expression level in placenta.
DR   ExpressionAtlas; B5MCE1; baseline and differential.
DR   Gene3D; 2.60.40.10; -; 3.
DR   InterPro; IPR007110; Ig-like_dom.
DR   InterPro; IPR036179; Ig-like_dom_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR003599; Ig_sub.
DR   InterPro; IPR003598; Ig_sub2.
DR   InterPro; IPR013106; Ig_V-set.
DR   Pfam; PF13895; Ig_2; 1.
DR   Pfam; PF07686; V-set; 1.
DR   SMART; SM00409; IG; 3.
DR   SMART; SM00408; IGc2; 2.
DR   SUPFAM; SSF48726; SSF48726; 3.
DR   PROSITE; PS50835; IG_LIKE; 2.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Proteomics identification {ECO:0000213|PeptideAtlas:B5MCE1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     34       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        35    331       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5002834332.
FT   DOMAIN      148    233       Ig-like. {ECO:0000259|PROSITE:PS50835}.
FT   DOMAIN      241    312       Ig-like. {ECO:0000259|PROSITE:PS50835}.
SQ   SEQUENCE   331 AA;  36669 MW;  B29EEF34C9224246 CRC64;
     MGPLSAPPCT QHITWKGLLL TASLLNFWNL PTTAQVIIEA KPPKVSEGKD VLLLVHNLPQ
     NLTGYIWYKG QMTDLYHYIT SYVVHGQIIY GPAYSGRETV YSNASLLIQN VTQEDAGSYT
     LHIIKRGDGT GGVTGYFTVT LYSETPKPSI SSSNLNPREV MEAVRLICDP ETPDASYLWL
     LNGQNLPMTH RLQLSKTNRT LYLFGVTKYI AGPYECEIRN PVSASRSDPV TLNLLHGPDL
     PRIYPSFTYY RSGENLDLSC FADSNPPAEY SWTINGKFQL SGQKLFIPQI TTNHSGLYAC
     SVRNSATGKE ISKSMIVKVS GPCHGNQTES H
//