ID   B5MC07_HUMAN            Unreviewed;       188 AA.
AC   B5MC07;
DT   14-OCT-2008, integrated into UniProtKB/TrEMBL.
DT   14-OCT-2008, sequence version 1.
DT   16-JAN-2019, entry version 66.
DE   SubName: Full=Anterior gradient protein 2 homolog {ECO:0000313|Ensembl:ENSP00000386025};
GN   Name=AGR2 {ECO:0000313|Ensembl:ENSP00000386025};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000386025, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000386025, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=12853948; DOI=10.1038/nature01782;
RA   Hillier L.W., Fulton R.S., Fulton L.A., Graves T.A., Pepin K.H.,
RA   Wagner-McPherson C., Layman D., Maas J., Jaeger S., Walker R.,
RA   Wylie K., Sekhon M., Becker M.C., O'Laughlin M.D., Schaller M.E.,
RA   Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E., Cordes M., Du H.,
RA   Sun H., Edwards J., Bradshaw-Cordum H., Ali J., Andrews S., Isak A.,
RA   Vanbrunt A., Nguyen C., Du F., Lamar B., Courtney L., Kalicki J.,
RA   Ozersky P., Bielicki L., Scott K., Holmes A., Harkins R., Harris A.,
RA   Strong C.M., Hou S., Tomlinson C., Dauphin-Kohlberg S.,
RA   Kozlowicz-Reilly A., Leonard S., Rohlfing T., Rock S.M.,
RA   Tin-Wollam A.-M., Abbott A., Minx P., Maupin R., Strowmatt C.,
RA   Latreille P., Miller N., Johnson D., Murray J., Woessner J.P.,
RA   Wendl M.C., Yang S.-P., Schultz B.R., Wallis J.W., Spieth J.,
RA   Bieri T.A., Nelson J.O., Berkowicz N., Wohldmann P.E., Cook L.L.,
RA   Hickenbotham M.T., Eldred J., Williams D., Bedell J.A., Mardis E.R.,
RA   Clifton S.W., Chissoe S.L., Marra M.A., Raymond C., Haugen E.,
RA   Gillett W., Zhou Y., James R., Phelps K., Iadanoto S., Bubb K.,
RA   Simms E., Levy R., Clendenning J., Kaul R., Kent W.J., Furey T.S.,
RA   Baertsch R.A., Brent M.R., Keibler E., Flicek P., Bork P., Suyama M.,
RA   Bailey J.A., Portnoy M.E., Torrents D., Chinwalla A.T., Gish W.R.,
RA   Eddy S.R., McPherson J.D., Olson M.V., Eichler E.E., Green E.D.,
RA   Waterston R.H., Wilson R.K.;
RT   "The DNA sequence of human chromosome 7.";
RL   Nature 424:157-164(2003).
RN   [2] {ECO:0000313|Ensembl:ENSP00000386025}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JUL-2011) to UniProtKB.
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DR   EMBL; AC073333; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; B5MC07; -.
DR   SMR; B5MC07; -.
DR   jPOST; B5MC07; -.
DR   MaxQB; B5MC07; -.
DR   PeptideAtlas; B5MC07; -.
DR   PRIDE; B5MC07; -.
DR   Ensembl; ENST00000401412; ENSP00000386025; ENSG00000106541.
DR   UCSC; uc064bsn.1; human.
DR   EuPathDB; HostDB:ENSG00000106541.11; -.
DR   HGNC; HGNC:328; AGR2.
DR   OpenTargets; ENSG00000106541; -.
DR   eggNOG; ENOG410IVR8; Eukaryota.
DR   eggNOG; ENOG4111K70; LUCA.
DR   GeneTree; ENSGT00530000063273; -.
DR   HOGENOM; HOG000231100; -.
DR   HOVERGEN; HBG006516; -.
DR   OMA; YSNMQKA; -.
DR   ChiTaRS; AGR2; human.
DR   Proteomes; UP000005640; Chromosome 7.
DR   Bgee; ENSG00000106541; Expressed in 156 organ(s), highest expression level in mucosa of sigmoid colon.
DR   ExpressionAtlas; B5MC07; baseline and differential.
DR   InterPro; IPR036249; Thioredoxin-like_sf.
DR   SUPFAM; SSF52833; SSF52833; 1.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Proteomics identification {ECO:0000213|MaxQB:B5MC07,
KW   ECO:0000213|PeptideAtlas:B5MC07};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     20       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        21    188       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5002836722.
SQ   SEQUENCE   188 AA;  21392 MW;  DA2E21B0224EC3DD CRC64;
     MEKIPVSAFL LLVALSYTLA RDTTVKPGAK KDTKDSRPKL PQTLSRGWGD QLIWTQTYEE
     ALYKSKTSNK PLMIIHHLDE CPHSQALKKV FAENKEIQKL AEQFVLLNLV YETTDKHLSP
     DGQYVPRIMF VDPSLTVRAD ITGRYSNRLY AYEPADTALC KCDLQFGCCP RVEHLYCCSD
     GTRGCMVR
//