ID   B4DYQ8_HUMAN            Unreviewed;       225 AA.
AC   B4DYQ8;
DT   23-SEP-2008, integrated into UniProtKB/TrEMBL.
DT   23-SEP-2008, sequence version 1.
DT   05-DEC-2018, entry version 76.
DE   SubName: Full=Cyclic nucleotide-gated cation channel alpha-4 {ECO:0000313|Ensembl:ENSP00000433399};
DE   SubName: Full=cDNA FLJ51400, highly similar to Cyclic nucleotide-gated ol factory channel subunit OCNC2 {ECO:0000313|EMBL:BAG63820.1};
GN   Name=CNGA4 {ECO:0000313|Ensembl:ENSP00000433399};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|EMBL:BAG63820.1};
RN   [1] {ECO:0000313|Ensembl:ENSP00000433399, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16554811; DOI=10.1038/nature04632;
RA   Taylor T.D., Noguchi H., Totoki Y., Toyoda A., Kuroki Y., Dewar K.,
RA   Lloyd C., Itoh T., Takeda T., Kim D.W., She X., Barlow K.F., Bloom T.,
RA   Bruford E., Chang J.L., Cuomo C.A., Eichler E., FitzGerald M.G.,
RA   Jaffe D.B., LaButti K., Nicol R., Park H.S., Seaman C., Sougnez C.,
RA   Yang X., Zimmer A.R., Zody M.C., Birren B.W., Nusbaum C., Fujiyama A.,
RA   Hattori M., Rogers J., Lander E.S., Sakaki Y.;
RT   "Human chromosome 11 DNA sequence and analysis including novel gene
RT   identification.";
RL   Nature 440:497-500(2006).
RN   [2] {ECO:0000313|EMBL:BAG63820.1}
RP   NUCLEOTIDE SEQUENCE.
RC   TISSUE=Testis {ECO:0000313|EMBL:BAG63820.1};
RA   Wakamatsu A., Yamamoto J., Kimura K., Ishii S., Watanabe K.,
RA   Sugiyama A., Murakawa K., Kaida T., Tsuchiya K., Fukuzumi Y.,
RA   Kumagai A., Oishi Y., Yamamoto S., Ono Y., Komori Y., Yamazaki M.,
RA   Kisu Y., Nishikawa T., Sugano S., Nomura N., Isogai T.;
RT   "NEDO human cDNA sequencing project focused on splicing variants.";
RL   Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases.
RN   [3] {ECO:0000313|Ensembl:ENSP00000433399}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (FEB-2012) to UniProtKB.
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DR   EMBL; AC022762; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AK302551; BAG63820.1; -; mRNA.
DR   UniGene; Hs.434618; -.
DR   SMR; B4DYQ8; -.
DR   PRIDE; B4DYQ8; -.
DR   Ensembl; ENST00000533426; ENSP00000433399; ENSG00000132259.
DR   UCSC; uc010raa.3; human.
DR   EuPathDB; HostDB:ENSG00000132259.12; -.
DR   HGNC; HGNC:2152; CNGA4.
DR   OpenTargets; ENSG00000132259; -.
DR   eggNOG; KOG0500; Eukaryota.
DR   eggNOG; ENOG410YWWI; LUCA.
DR   GeneTree; ENSGT00940000159415; -.
DR   HOGENOM; HOG000070172; -.
DR   Proteomes; UP000005640; Chromosome 11.
DR   Bgee; ENSG00000132259; Expressed in 78 organ(s), highest expression level in right uterine tube.
DR   ExpressionAtlas; B4DYQ8; baseline and differential.
DR   CDD; cd00038; CAP_ED; 1.
DR   Gene3D; 2.60.120.10; -; 1.
DR   InterPro; IPR018490; cNMP-bd-like.
DR   InterPro; IPR018488; cNMP-bd_CS.
DR   InterPro; IPR000595; cNMP-bd_dom.
DR   InterPro; IPR014710; RmlC-like_jellyroll.
DR   Pfam; PF00027; cNMP_binding; 1.
DR   SMART; SM00100; cNMP; 1.
DR   SUPFAM; SSF51206; SSF51206; 1.
DR   PROSITE; PS00888; CNMP_BINDING_1; 1.
DR   PROSITE; PS50042; CNMP_BINDING_3; 1.
PE   2: Evidence at transcript level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     16       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        17    225       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5014085112.
FT   DOMAIN      117    195       Cyclic nucleotide-binding.
FT                                {ECO:0000259|PROSITE:PS50042}.
SQ   SEQUENCE   225 AA;  25645 MW;  68BE7447C1640BF1 CRC64;
     MVFPVMYNLI ILVCRACFPD LQHGYLVAWL VLDYTSDLLY LLDMVVRFHT DHALVKKYMK
     LQHVNRKLER RVIDWYQHLQ INKKMTNEVA ILQHLPERLR AEVAVSVHLS TLSRVQIFQN
     CEASLLEELV LKLQPQTYSP GEYVCRKGDI GQEMYIIREG QLAVVADDGI TQYAVLGAGL
     YFGEISIINI KGGYPSICSR DKDGWGRGEQ QSPVLGPDST SGLNF
//