ID   B4DYM4_HUMAN            Unreviewed;       883 AA.
AC   B4DYM4;
DT   23-SEP-2008, integrated into UniProtKB/TrEMBL.
DT   23-SEP-2008, sequence version 1.
DT   16-JAN-2019, entry version 70.
DE   SubName: Full=SUN domain-containing ossification factor {ECO:0000313|Ensembl:ENSP00000476704};
DE   SubName: Full=cDNA FLJ60972 {ECO:0000313|EMBL:BAG63786.1};
GN   Name=SUCO {ECO:0000313|Ensembl:ENSP00000476704};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|EMBL:BAG63786.1};
RN   [1] {ECO:0000313|Ensembl:ENSP00000476704, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16710414; DOI=10.1038/nature04727;
RA   Gregory S.G., Barlow K.F., McLay K.E., Kaul R., Swarbreck D.,
RA   Dunham A., Scott C.E., Howe K.L., Woodfine K., Spencer C.C.,
RA   Jones M.C., Gillson C., Searle S., Zhou Y., Kokocinski F.,
RA   McDonald L., Evans R., Phillips K., Atkinson A., Cooper R., Jones C.,
RA   Hall R.E., Andrews T.D., Lloyd C., Ainscough R., Almeida J.P.,
RA   Ambrose K.D., Anderson F., Andrew R.W., Ashwell R.I., Aubin K.,
RA   Babbage A.K., Bagguley C.L., Bailey J., Beasley H., Bethel G.,
RA   Bird C.P., Bray-Allen S., Brown J.Y., Brown A.J., Buckley D.,
RA   Burton J., Bye J., Carder C., Chapman J.C., Clark S.Y., Clarke G.,
RA   Clee C., Cobley V., Collier R.E., Corby N., Coville G.J., Davies J.,
RA   Deadman R., Dunn M., Earthrowl M., Ellington A.G., Errington H.,
RA   Frankish A., Frankland J., French L., Garner P., Garnett J., Gay L.,
RA   Ghori M.R., Gibson R., Gilby L.M., Gillett W., Glithero R.J.,
RA   Grafham D.V., Griffiths C., Griffiths-Jones S., Grocock R.,
RA   Hammond S., Harrison E.S., Hart E., Haugen E., Heath P.D., Holmes S.,
RA   Holt K., Howden P.J., Hunt A.R., Hunt S.E., Hunter G., Isherwood J.,
RA   James R., Johnson C., Johnson D., Joy A., Kay M., Kershaw J.K.,
RA   Kibukawa M., Kimberley A.M., King A., Knights A.J., Lad H., Laird G.,
RA   Lawlor S., Leongamornlert D.A., Lloyd D.M., Loveland J., Lovell J.,
RA   Lush M.J., Lyne R., Martin S., Mashreghi-Mohammadi M., Matthews L.,
RA   Matthews N.S., McLaren S., Milne S., Mistry S., Moore M.J.,
RA   Nickerson T., O'Dell C.N., Oliver K., Palmeiri A., Palmer S.A.,
RA   Parker A., Patel D., Pearce A.V., Peck A.I., Pelan S., Phelps K.,
RA   Phillimore B.J., Plumb R., Rajan J., Raymond C., Rouse G.,
RA   Saenphimmachak C., Sehra H.K., Sheridan E., Shownkeen R., Sims S.,
RA   Skuce C.D., Smith M., Steward C., Subramanian S., Sycamore N.,
RA   Tracey A., Tromans A., Van Helmond Z., Wall M., Wallis J.M., White S.,
RA   Whitehead S.L., Wilkinson J.E., Willey D.L., Williams H., Wilming L.,
RA   Wray P.W., Wu Z., Coulson A., Vaudin M., Sulston J.E., Durbin R.,
RA   Hubbard T., Wooster R., Dunham I., Carter N.P., McVean G., Ross M.T.,
RA   Harrow J., Olson M.V., Beck S., Rogers J., Bentley D.R., Banerjee R.,
RA   Bryant S.P., Burford D.C., Burrill W.D., Clegg S.M., Dhami P.,
RA   Dovey O., Faulkner L.M., Gribble S.M., Langford C.F., Pandian R.D.,
RA   Porter K.M., Prigmore E.;
RT   "The DNA sequence and biological annotation of human chromosome 1.";
RL   Nature 441:315-321(2006).
RN   [2] {ECO:0000313|EMBL:BAG63786.1}
RP   NUCLEOTIDE SEQUENCE.
RC   TISSUE=Testis {ECO:0000313|EMBL:BAG63786.1};
RA   Wakamatsu A., Yamamoto J., Kimura K., Ishii S., Watanabe K.,
RA   Sugiyama A., Murakawa K., Kaida T., Tsuchiya K., Fukuzumi Y.,
RA   Kumagai A., Oishi Y., Yamamoto S., Ono Y., Komori Y., Yamazaki M.,
RA   Kisu Y., Nishikawa T., Sugano S., Nomura N., Isogai T.;
RT   "NEDO human cDNA sequencing project focused on splicing variants.";
RL   Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases.
RN   [3] {ECO:0000213|PubMed:18669648}
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX   PubMed=18669648; DOI=10.1073/pnas.0805139105;
RA   Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E.,
RA   Elledge S.J., Gygi S.P.;
RT   "A quantitative atlas of mitotic phosphorylation.";
RL   Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008).
RN   [4] {ECO:0000213|PubMed:23186163}
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX   PubMed=23186163;
RA   Zhou H., Di Palma S., Preisinger C., Peng M., Polat A.N., Heck A.J.,
RA   Mohammed S.;
RT   "Toward a comprehensive characterization of a human cancer cell
RT   phosphoproteome.";
RL   J. Proteome Res. 12:260-271(2013).
RN   [5] {ECO:0000313|Ensembl:ENSP00000476704}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (DEC-2013) to UniProtKB.
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DR   EMBL; KF455074; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; Z94054; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; Z96050; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AK302509; BAG63786.1; -; mRNA.
DR   RefSeq; NP_001269679.1; NM_001282750.1.
DR   UniGene; Hs.204559; -.
DR   jPOST; B4DYM4; -.
DR   MaxQB; B4DYM4; -.
DR   PRIDE; B4DYM4; -.
DR   Ensembl; ENST00000610051; ENSP00000476704; ENSG00000094975.
DR   GeneID; 51430; -.
DR   UCSC; uc010pmn.4; human.
DR   CTD; 51430; -.
DR   EuPathDB; HostDB:ENSG00000094975.13; -.
DR   HGNC; HGNC:1240; SUCO.
DR   OpenTargets; ENSG00000094975; -.
DR   eggNOG; KOG1396; Eukaryota.
DR   eggNOG; ENOG41116S0; LUCA.
DR   GeneTree; ENSGT00390000013502; -.
DR   HOGENOM; HOG000070169; -.
DR   HOVERGEN; HBG107549; -.
DR   OrthoDB; 890782at2759; -.
DR   ChiTaRS; SUCO; human.
DR   GenomeRNAi; 51430; -.
DR   Proteomes; UP000005640; Chromosome 1.
DR   Bgee; ENSG00000094975; Expressed in 235 organ(s), highest expression level in caput epididymis.
DR   ExpressionAtlas; B4DYM4; baseline and differential.
DR   Gene3D; 2.60.120.260; -; 1.
DR   InterPro; IPR008979; Galactose-bd-like_sf.
DR   InterPro; IPR012919; SUN_dom.
DR   Pfam; PF07738; Sad1_UNC; 1.
DR   SUPFAM; SSF49785; SSF49785; 1.
DR   PROSITE; PS51469; SUN; 1.
PE   1: Evidence at protein level;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Proteomics identification {ECO:0000213|MaxQB:B4DYM4,
KW   ECO:0000213|PeptideAtlas:B4DYM4};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     29       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        30    883       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5014567694.
FT   DOMAIN      247    416       SUN. {ECO:0000259|PROSITE:PS51469}.
FT   COILED      615    635       {ECO:0000256|SAM:Coils}.
FT   COILED      821    841       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   883 AA;  98284 MW;  0059225E2BE16962 CRC64;
     MKKHRRALAL VSCLFLCSLV WLPSWRVCCK ESSSASASSY YSQDDNCALE NEDVQFQKKN
     TESKKLSPPV VETLPTVDLH EESSNAVVDS ETVENISSSS TSEITPISKL DEIEKSGTIP
     IAKPSETEQS ETDCDVGEAL DASAPIEQPS FVSPPDSLVG QHIENVSSSH GKGKITKSEF
     ESKVSASEQG GGDPKSALNA SDNLKNESSD YTKPGDIDPT SVASPKDPED IPTFDEWKKK
     VMEVEKEKSQ SMHASSNGGS HATKKVQKNR NNYASVECGA KILAANPEAK STSAILIENM
     DLYMLNPCST KIWFVIELCE PIQVKQLDIA NYELFSSTPK DFLVSISDRY PTNKWIKLGT
     FHGRDERNVQ SFPLDEQMYA KYVKMFIKYI KVELLSHFGS EHFCPLSLIR VFGTSMVEEY
     EEIADSQYHS ERQELFDEDY DYPLDYNTGE DKSSKNLLGS ATNAILNMVN IAANILGAKT
     EDLTEGNKSI SENATATAAP KMPESTPVST PVPSPEYVTT EVHTHDMEPS TPDTPKESPI
     VQLVQEEEEE ASPSTVTLLG SGEQEDESSP WYRKQMEEMQ KAFNKTIVKL QNTSRIAEEQ
     DQRQTEAIQL LQAQLTNMTQ LVSNLSATVA ELKREVSDRQ SYLVISLVLC VVLGLMLCMQ
     RCRNTSQFDG DYISKLPKSN QYPSPKRCFS SYDDMNLKRR TSFPLMRSKS LQLTGKEVDP
     NDLYIVEPLK FSPEKKKKRC KYKIEKIETI KPEEPLHPIA NGDIKGRKPF TNQRDFSNMG
     EVYHSSYKGP PSEGSSETSS QSEESYFCGI SACTSLCNGQ SQKTKTEKRA LKRRRSKVQD
     QGKLIKTLIQ TKSGSLPSLH DIIKGNKEIT VGTFGVTAVS GHI
//